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Paper · 39759879

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.

Zlinska V and 22 others. Mol Ther Nucleic Acids, 2025. Cited by 13 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer. Papers, record 39759879. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39759879

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.
PubMed
Journal
Mol Ther Nucleic Acids
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
13
iCite
Relative citation ratio, by iCite
1.88, provisional
iCite
Revised in PubMed
2025-01-07
PubMed

Authors23

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Zlinska VVladimira
2Feketova ZZuzana
3Czyrek AAleksandra
4Chudzian JJulia
5Zivkovic MLMartina Lenarcic
6Ursachi VCVlad-Constantin
7Dudeja PPooja
8Fafilek BBohumil
9Rynes JJan
10Rico-Llanos GGustavo

1 to 10 of 23Source PubMed

See all 23 authors

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
120,940,169Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease.J Biochem2011https://conductscience.org/library/papers/20940169PubMed
230,228,226The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.Sci Signal2018https://conductscience.org/library/papers/30228226PubMed
311,447,289Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways.Proc Natl Acad Sci U S A2001https://conductscience.org/library/papers/11447289PubMed
434,467,321A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells.JACS Au2021https://conductscience.org/library/papers/34467321PubMed
537,270,847RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.Cancer Discov2023https://conductscience.org/library/papers/37270847PubMed
617,008,716Elucidation of the mechanism of the regulatory function of the Ig1 module of the fibroblast growth factor receptor 1.Protein Sci2006https://conductscience.org/library/papers/17008716PubMed
739,158,730Uncovering key steps in FGF12 cellular release reveals a common mechanism for unconventional FGF protein secretion.Cell Mol Life Sci2024https://conductscience.org/library/papers/39158730PubMed
826,725,515Mechanism of FGF receptor dimerization and activation.Nat Commun2016https://conductscience.org/library/papers/26725515PubMed
930,600,916TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure.ChemMedChem2019https://conductscience.org/library/papers/30600916PubMed
1033,952,673An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice.Sci Transl Med2021https://conductscience.org/library/papers/33952673PubMed

1 to 10 of 27

See all 27 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 13 citations.

PMIDTitleJournalYearIn PapersSource
42,633,326Advances in FGF/FGFR Signaling: Implications for Disease and Therapy.MedComm (2020)2026https://conductscience.org/library/papers/42633326PubMed
42,542,977Mechanisms and Manifestations of Ligand Bias in Signaling: Focus on Receptor Tyrosine Kinases.Chem Rev2026https://conductscience.org/library/papers/42542977PubMed
42,387,574Structure-function relationship in FGF signaling: rational design of highly stable FGF2 variants and their effect on cell growth, metabolism, and survival.J Biol Eng2026https://conductscience.org/library/papers/42387574PubMed
41,584,352Unraveling the FGFR-RNA splicing axis: Mechanisms, oncogenic crosstalks and innovations for therapeutic purpose.Acta Pharm Sin B2026https://conductscience.org/library/papers/41584352PubMed
41,390,521ARMH4 accelerates aging by maintaining a positive-feedback growth signaling circuit.Nat Commun2025https://conductscience.org/library/papers/41390521PubMed
40,370,647Application of multivalent aptamers in tumor diagnosis, analysis and therapy (Review).Oncol Lett2025https://conductscience.org/library/papers/40370647PubMed
40,257,501Increased thermal stability of FGF10 leads to ectopic signaling during development.Cell Mol Life Sci2025https://conductscience.org/library/papers/40257501PubMed
40,092,750Lockpicking FGFR1 with aptamer-based technology.Mol Ther Nucleic Acids2025https://conductscience.org/library/papers/40092750PubMed

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FGFR12,260PubTator's text mininghttps://conductscience.org/library/genes/2260NCBI Gene
FGFR22,263PubTator's text mininghttps://conductscience.org/library/genes/2263NCBI Gene
FGFR42,264PubTator's text mininghttps://conductscience.org/library/genes/2264NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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