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Paper · 34467321

A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells.

Eguchi A and 9 others. JACS Au, 2021. Cited by 13 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells. Papers, record 34467321. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/34467321

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells.
PubMed
Journal
JACS Au
PubMed
Year
2021
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
13
iCite
Relative citation ratio, by iCite
0.75
iCite
Revised in PubMed
2021-09-04
PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Eguchi AAkihiro
2Ueki AAyaka
3Hoshiyama JJunya
4Kuwata KKeiko
5Chikaoka YYoko
6Kawamura TTakeshi
7Nagatoishi SSatoruhttps://orcid.org/0000-0002-0794-3963
8Tsumoto KKouheihttps://orcid.org/0000-0001-7643-5164
9Ueki RRyosukehttps://orcid.org/0000-0002-5433-5354
10Sando SShinsukehttps://orcid.org/0000-0003-0275-7237

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References46

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
118,381,441FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.Cancer Res2008https://conductscience.org/library/papers/18381441PubMed
225,772,309The Fibroblast Growth Factor signaling pathway.Wiley Interdiscip Rev Dev Biol2015https://conductscience.org/library/papers/25772309PubMed
327,088,106From selection hits to clinical leads: progress in aptamer discovery.Mol Ther Methods Clin Dev2016https://conductscience.org/library/papers/27088106PubMed
419,411,071Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941.Cancer Cell2009https://conductscience.org/library/papers/19411071PubMed
511,369,216Epidermal growth factor receptor signaling.Curr Biol2001https://conductscience.org/library/papers/11369216PubMed
630,746,545DNA aptamer assemblies as fibroblast growth factor mimics and their application in stem cell culture.Chem Commun (Camb)2019https://conductscience.org/library/papers/30746545PubMed
725,223,895A DNA aptamer to c-Met inhibits cancer cell migration.Chem Commun (Camb)2014https://conductscience.org/library/papers/25223895PubMed
826,725,515Mechanism of FGF receptor dimerization and activation.Nat Commun2016https://conductscience.org/library/papers/26725515PubMed
927,230,412FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival.Mod Pathol2016https://conductscience.org/library/papers/27230412PubMed
1032,961,472Prevention and treatment of FGFR inhibitor-associated toxicities.Crit Rev Oncol Hematol2020https://conductscience.org/library/papers/32961472PubMed

1 to 10 of 46

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Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 13 citations.

PMIDTitleJournalYearIn PapersSource
42,559,254Reprogramming FGFR isoform specificity in FGF2 by deep mutational scanning.Chem Sci2026https://conductscience.org/library/papers/42559254PubMed
41,584,352Unraveling the FGFR-RNA splicing axis: Mechanisms, oncogenic crosstalks and innovations for therapeutic purpose.Acta Pharm Sin B2026https://conductscience.org/library/papers/41584352PubMed
41,054,857TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition.Adv Sci (Weinh)2026https://conductscience.org/library/papers/41054857PubMed
39,759,879Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.Mol Ther Nucleic Acids2025https://conductscience.org/library/papers/39759879PubMed
36,524,009Therapeutic Potential of Aptamer-Protein Interactions.ACS Pharmacol Transl Sci2022https://conductscience.org/library/papers/36524009PubMed
35,573,821Current Advances in Aptamer-based Biomolecular Recognition and Biological Process Regulation.Chem Res Chin Univ2022https://conductscience.org/library/papers/35573821PubMed

Genes13

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AKT1207PubTator's text mininghttps://conductscience.org/library/genes/207NCBI Gene
EGFR1,956PubTator's text mininghttps://conductscience.org/library/genes/1956NCBI Gene
ERBB22,064PubTator's text mininghttps://conductscience.org/library/genes/2064NCBI Gene
FGF12,246PubTator's text mininghttps://conductscience.org/library/genes/2246NCBI Gene
FGF102,255PubTator's text mininghttps://conductscience.org/library/genes/2255NCBI Gene
FGF22,247PubTator's text mininghttps://conductscience.org/library/genes/2247NCBI Gene
FGF72,252PubTator's text mininghttps://conductscience.org/library/genes/2252NCBI Gene
FGFR12,260PubTator's text mininghttps://conductscience.org/library/genes/2260NCBI Gene
FGFR22,263PubTator's text mininghttps://conductscience.org/library/genes/2263NCBI Gene
FGFR32,261PubTator's text mininghttps://conductscience.org/library/genes/2261NCBI Gene

1 to 10 of 13

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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