Paper · 41261306
Translating genomic insights into therapy: an NGS-based mutation profiling study in breast cancer.
Bhavnagari HM and 4 others. Med Oncol, 2025. Cited by 0 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Translating genomic insights into therapy: an NGS-based mutation profiling study in breast cancer. Papers, record 41261306. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41261306
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Translating genomic insights into therapy: an NGS-based mutation profiling study in breast cancer.
- PubMed
Topics14
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Breast Neoplasms | Major topic |
| High-Throughput Nucleotide Sequencing | Major topic |
| Mutation | Major topic |
| Carcinoma, Ductal, Breast | Major topic |
| Humans | |
| Female | |
| Middle Aged | |
| Class I Phosphatidylinositol 3-Kinases | |
| Adult | |
| Aged | |
| DNA Copy Number Variations | |
| Genomics | |
| DNA Mutational Analysis | |
| Biomarkers, Tumor |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References34
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 31,091,374 | Alpelisib for PIK3CA-Mutated, Hormone Receptor-Positive Advanced Breast Cancer. | N Engl J Med | 2019 | https://conductscience.org/library/papers/31091374 | PubMed |
| 2 | 37,817,699 | Application Of Multigene Panel Detection In Breast Cancer. | J Pak Med Assoc | 2023 | https://conductscience.org/library/papers/37817699 | PubMed |
| 3 | 38,751,471 | Breast cancer gene expression signatures: development and clinical significance-a narrative review. | Transl Breast Cancer Res | 2023 | https://conductscience.org/library/papers/38751471 | PubMed |
| 4 | 33,246,021 | Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: final overall survival results from SOLAR-1. | Ann Oncol | 2021 | https://conductscience.org/library/papers/33246021 | PubMed |
| 5 | 16,720,680 | Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. | J Clin Oncol | 2006 | https://conductscience.org/library/papers/16720680 | PubMed |
| 6 | 27,557,300 | 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer. | N Engl J Med | 2016 | https://conductscience.org/library/papers/27557300 | PubMed |
| 7 | 32,256,585 | Somatic Mutations in HER2 and Implications for Current Treatment Paradigms in HER2-Positive Breast Cancer. | J Oncol | 2020 | https://conductscience.org/library/papers/32256585 | PubMed |
| 8 | 27,939,064 | HER2-positive breast cancer. | Lancet | 2017 | https://conductscience.org/library/papers/27939064 | PubMed |
| 9 | 33,177,006 | Durable Clinical Activity to the AKT Inhibitor Ipatasertib in a Heavily Pretreated Patient With an AKT1 E17K Mutant Metastatic Breast Cancer. | Clin Breast Cancer | 2021 | https://conductscience.org/library/papers/33177006 | PubMed |
| 10 | 26,297,356 | Development and verification of the PAM50-based Prosigna breast cancer gene signature assay. | BMC Med Genomics | 2015 | https://conductscience.org/library/papers/26297356 | PubMed |
1 to 10 of 34
See all 34 referencesCited by0
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 0 citations.
None in this release.
Genes7
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CD274 | 29,126 | PubTator's text mining | https://conductscience.org/library/genes/29126 | NCBI Gene |
| CDKN2A | 1,029 | PubTator's text mining | https://conductscience.org/library/genes/1029 | NCBI Gene |
| EGFR | 1,956 | PubTator's text mining | https://conductscience.org/library/genes/1956 | NCBI Gene |
| ERBB2 | 2,064 | PubTator's text mining | https://conductscience.org/library/genes/2064 | NCBI Gene |
| PIK3CA | 5,290 | PubTator's text mining | https://conductscience.org/library/genes/5290 | NCBI Gene |
| PTEN | 5,728 | PubTator's text mining | https://conductscience.org/library/genes/5728 | NCBI Gene |
| TP53 | 7,157 | PubTator's text mining | https://conductscience.org/library/genes/7157 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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