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Paper · 42429613

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma.

Hu Y and 5 others. Adv Sci (Weinh), 2026. Cited by 3 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma. Papers, record 42429613. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42429613

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma.
PubMed
Journal
Adv Sci (Weinh)
PubMed
Year
2026
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
3
iCite
Revised in PubMed
2026-08-13
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hu YYi
2Lin CCaiyan
3Zhang LLijie
4Jiang XXue
5Li HHuawen
6Wu YYangzhehttps://orcid.org/0000-0002-5270-2747

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Carcinoma, HepatocellularMajor topic
Liver NeoplasmsMajor topic
Gastrointestinal MicrobiomeMajor topic
Liver DiseasesMajor topic
Humans
Disease Progression
Animals

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
32270950National Natural Science Foundation of ChinaPubMed
2025A1515010628Natural Science Foundation of Guangdong Province of ChinaPubMed
2024A1515010551Natural Science Foundation of Guangdong Province of ChinaPubMed
YNXM20210305Startup Foundation of the Zhuhai People's HospitalPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References329

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
128,467,925Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease.Cell Metab2017https://conductscience.org/library/papers/28467925PubMed
227,423,426Liver sinusoidal endothelial cells: Physiology and role in liver diseases.J Hepatol2017https://conductscience.org/library/papers/27423426PubMed
332,901,017Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity.Nat Commun2020https://conductscience.org/library/papers/32901017PubMed
438,754,417Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.Cell Host Microbe2024https://conductscience.org/library/papers/38754417PubMed
540,954,286Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis.Nat Metab2025https://conductscience.org/library/papers/40954286PubMed
625,157,983Hypoxia inducible factors in liver disease and hepatocellular carcinoma: current understanding and future directions.J Hepatol2014https://conductscience.org/library/papers/25157983PubMed
732,937,687Obesity and binge alcohol intake are deadly combination to induce steatohepatitis: A model of high-fat diet and binge ethanol intake.Clin Mol Hepatol2020https://conductscience.org/library/papers/32937687PubMed
836,630,995Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.Hepatology2023https://conductscience.org/library/papers/36630995PubMed
934,140,495Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma.Nat Commun2021https://conductscience.org/library/papers/34140495PubMed
1039,609,906Which dietary patterns fend off nonalcoholic fatty liver disease? A systematic review of observational and interventional studies.BMC Nutr2024https://conductscience.org/library/papers/39609906PubMed

1 to 10 of 329

See all 329 references

Cited by4

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 3 citations.

PMIDTitleJournalYearIn PapersSource
42,711,910Gut Microbiota-Derived Indole-3-Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2-Mediated Ferroptosis Suppression.Adv Sci (Weinh)2026https://conductscience.org/library/papers/42711910PubMed
42,691,205Gut-Intervertebral Disc Axis: Gut Microbiome-Driven Immune-Metabolic Imbalance and Intervertebral Disc Degeneration.J Cell Physiol2026https://conductscience.org/library/papers/42691205PubMed
42,614,744Perioperative gut microbial ecology: a new frontier for improving the prognosis of hepatocellular carcinoma surgery.Precis Clin Med2026https://conductscience.org/library/papers/42614744PubMed
42,429,613Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma.Adv Sci (Weinh)2026https://conductscience.org/library/papers/42429613PubMed

Genes5

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AHR196PubTator's text mininghttps://conductscience.org/library/genes/196NCBI Gene
GPBAR1151,306PubTator's text mininghttps://conductscience.org/library/genes/151306NCBI Gene
HCAR2338,442PubTator's text mininghttps://conductscience.org/library/genes/338442NCBI Gene
NR1H49,971PubTator's text mininghttps://conductscience.org/library/genes/9971NCBI Gene
NR1I28,856PubTator's text mininghttps://conductscience.org/library/genes/8856NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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