3 articles found

Abstract

Understanding PrEP: Perceptions and Misconceptions Amongst Men Who Have Sex With Men in Upstate South Carolina

12 February 2026

Despite the effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV, uptake among men who have sex with men (MSM) in Upstate South Carolina remains limited. This study investigates barriers to PrEP access and utilization in this population to guide targeted public health strategies. A cross-sectional survey of MSM aged 18 and older was conducted to collect demographic information, perceptions and misconceptions about PrEP, and reported obstacles to accessing it. Pearson correlation tests were used to examine associations between participant characteristics and identified barriers. Social stigma, financial constraints, and limited provider engagement emerged as the most frequently reported barriers. Notably, lower socioeconomic status was significantly associated with perceptions of discrimination in healthcare settings, while racial and ethnic minority participants were more likely to express a desire for proactive discussions about PrEP with their providers. Participants also emphasized the need for clearer pathways to locate PrEP access programs and indicated that reducing wait times for initiation would improve their likelihood of starting PrEP. These results highlight the need for interventions that address both social and structural barriers to PrEP uptake. Expanding financial support, increasing provider involvement, and implementing statewide public awareness efforts are critical to improving access and reducing disparities among MSM in this region.

Jack Golder

Christian Zanetti-Weeks

Evan Lagerberg

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