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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,761 to 4,780 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Cohort 1: Participants Aged 9 to 17 Years vs Cohort 2: Participants Aged 18 to 49 Years: Number of Participants With Medically Attended Adverse Events (MAAEs)27 of 641

35 of 658

-1.1 points

-3.5 to 1.3

1,299NCT05513053

Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.

Cohort 1: Participants Aged 9 to 17 Years vs Cohort 2: Participants Aged 18 to 49 Years: serious adverse events3 of 641

7 of 658

-0.6 points

-1.8 to 0.5

1,299NCT05513053

Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.

Proactive Group vs Reactive Group: serious adverse events16 of 649

6 of 649

1.5 points

0.1 to 3.1

1,298NCT00632411

Evaluating a Telephone-Based Smoking Cessation Program Among People in the Military (The AFIII Study)

Aggrenox Capsule vs Acetylsalicylic Acid (ASA) 81 mg Tablet: serious adverse events178 of 655

167 of 639

1.0 points

-3.8 to 5.8

1,294NCT00311402

JASAP: Japanese Aggrenox Stroke Prevention vs. Aspirin Programme

Symbicort Turbuhaler (Experimental) vs Oxis Turbuhaler (Active Comparator): serious adverse events43 of 636

45 of 657

-0.1 points

-2.9 to 2.7

1,293NCT01069289

Efficacy and Safety Study of Symbicort® Turbuhaler® Versus Oxis® Turbuhaler® in Chronic Obstructive Pulmonary Disease (COPD) Patients

GBC+PIPT vs Guideline Based Care: Number of Patients Who Reported Transition From Acute to Chronic Low Back Pain (cLBP)312 of 658

318 of 635

-2.7 points

-8.1 to 2.8

1,293NCT02647658

Targeted Interventions to Prevent Chronic Low Back Pain in High Risk Patients

5 mg Risedronate vs 150 mg Risedronate: Number of Participants With New Vertebral Fracture at Month 12, ITT Population8 of 642

8 of 650

0.0 points

-1.3 to 1.4

1,292NCT00247273

A Study of Monthly Risedronate for Osteoporosis

5 mg Risedronate vs 150 mg Risedronate: Number of Participants With New Vertebral Fracture at Month 24, ITT Population14 of 642

14 of 650

0.0 points

-1.6 to 1.7

1,292NCT00247273

A Study of Monthly Risedronate for Osteoporosis

5 mg Risedronate vs 150 mg Risedronate: serious adverse events51 of 642

77 of 650

-3.9 points

-7.2 to -0.6

1,292NCT00247273

A Study of Monthly Risedronate for Osteoporosis

Icodec vs IcoSema: deaths from any cause3 of 645

2 of 646

0.2 points

-0.7 to 1.1

1,291NCT05352815

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec

Arm B - Fluvoxamine 50 vs Arm B - Placebo: serious adverse events3 of 676

6 of 615

-0.5 points

-1.7 to 0.5

1,291NCT05890586

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm B (Fluvoxamine)

Best Practice Clinic-Based Care vs Telehealth Care: Number of Participants Who Report High Level of Satisfaction With Hypertension Care at Six Months.205 of 678

241 of 610

-9.3 points

-14.4 to -4.1

1,288NCT02996565

Pragmatic Trial Comparing Telehealth Care and Optimized Clinic-Based Care for Uncontrolled High Blood Pressure

Nirmatrelvir 300 mg + Ritonavir 100 mg vs Placebo: deaths from any cause0 of 654

1 of 634

-0.2 points

-0.9 to 0.4

1,288NCT05011513

Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients (EPIC-SR).

Nirmatrelvir 300 mg + Ritonavir 100 mg vs Placebo: serious adverse events8 of 654

13 of 634

-0.8 points

-2.4 to 0.6

1,288NCT05011513

Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients (EPIC-SR).

Icodec vs IcoSema: serious adverse events69 of 644

59 of 644

1.6 points

-1.7 to 4.8

1,288NCT05352815

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec

Placebo + Letrozole 2.5 mg vs Lapatinib 1500 mg + Letrozole 2.5 mg: Number of Participants With PFS in the Intent-To-Treat (ITT) Population as Assessed by the Investigator476 of 644

413 of 642

9.6 points

4.5 to 14.6

1,286NCT00073528

Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer

Placebo + Letrozole 2.5 mg vs Lapatinib 1500 mg + Letrozole 2.5 mg: Number of Participants With Evidence of Brain Metastases From the ITT Population4 of 644

6 of 642

-0.3 points

-1.5 to 0.8

1,286NCT00073528

Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer

Gain-Framed Counseling vs Standard Care Counseling: 7 Day Abstinence148 of 524

202 of 762

1.7 points

-3.2 to 6.7

1,286NCT00589277

Message Framing for Telephone Quitline Callers

Atezolizumab With Paclitaxel, Carboplatin and Bevacizumab vs Placebo With Paclitaxel, Carboplatin and Bevacizumab: serious adverse events304 of 642

215 of 644

14.0 points

8.6 to 19.2

1,286NCT03038100

A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Treatment vs Placebo: Rate of All-Cause Study Medicine Discontinuation or Withdrawal97 of 645

63 of 641

5.2 points

1.6 to 8.8

1,286NCT04308668

Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=239"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=239

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT05513053-8d124c6a",
        "title": "Cohort 1: Participants Aged 9 to 17 Years vs Cohort 2: Participants Aged 18 to 49 Years: Number of Participants With Medically Attended Adverse Events (MAAEs)",
        "summary": "27 of 641 against 35 of 658; risk difference -1.1 points, 95% interval -3.5 to 1.3; NCT05513053, Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.",
        "record": "/library/comparisons/NCT05513053-8d124c6a",
        "nct_id": "NCT05513053",
        "kind": "outcome",
        "participants": 1299,
        "risk_difference": {
          "value": -0.01106980449430743,
          "lower": -0.03483570959191211,
          "upper": 0.012534972395294552
        },
        "group_1": "27 of 641",
        "group_2": "35 of 658",
        "difference": "-1.1 points",
        "interval": "-3.5 to 1.3",
        "trial_title": "Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age."
      },
      {
        "id": "NCT05513053-sae",
        "title": "Cohort 1: Participants Aged 9 to 17 Years vs Cohort 2: Participants Aged 18 to 49 Years: serious adverse events",
        "summary": "3 of 641 against 7 of 658; risk difference -0.6 points, 95% interval -1.8 to 0.5; NCT05513053, Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.",
        "record": "/library/comparisons/NCT05513053-sae",
        "nct_id": "NCT05513053",
        "kind": "serious-adverse-events",
        "participants": 1299,
        "risk_difference": {
          "value": -0.005958110664852126,
          "lower": -0.017533840869292397,
          "upper": 0.004567126080172845
        },
        "group_1": "3 of 641",
        "group_2": "7 of 658",
        "difference": "-0.6 points",
        "interval": "-1.8 to 0.5",
        "trial_title": "Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age."
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=240",
  "request_id": "9LPcez_ty0vvZRff"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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