Disease · MONDO_0005119
anthrax infection
6 sourcesdiseases-2026-09-18-0.1.0
Cite this record
ConductScience Library. anthrax infection. Diseases, record MONDO_0005119. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0005119
On this page
Disease
Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.
- Other names
Anthrax (disorder), Anthrax NOS, Anthrax NOS (disorder), Anthrax, unspecified, Bacillus anthracis caused disease or disorder, Bacillus anthracis disease or disorder, Bacillus anthracis infectious disease, Charbon, Infection due to Bacillus anthracis, Milzbrand, OTHER ANTHRAX MANIFEST, Other specified anthrax manifestations, Other specified anthrax manifestations (disorder), Other specified manifestations of anthrax, Splenic fever, [X]Anthrax, unspecified, [X]Anthrax, unspecified (disorder), anthrax, anthrax disease
- Open Targets
- Highest stage of its drugs
- Approval, for 6 of its 7 drugs, from DailyMed, FDA, PMDA and TTD
- Open Targets
Drugs7
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Drug | ChEMBL ID | Type | Open Targets' stage | Stage reported by | Reports | Of them trials | Trials shown here | Source |
|---|---|---|---|---|---|---|---|---|
| RAXIBACUMAB | CHEMBL2108638 | Antibody | Approval | DailyMed and TTD | 4 | 2 | 2 | Drugs and targets |
| BACILLUS ANTHRACIS PROTECTIVE ANTIGEN, ADSORBED | CHEMBL6068494 | Approval | FDA | 3 | 0 | 0 | Drugs and targets | |
| OBILTOXAXIMAB | CHEMBL3544926 | Antibody | Approval | FDA and TTD | 3 | 0 | 0 | Drugs and targets |
| DOXYCYCLINE | CHEMBL1200699 | Small molecule | Approval | DailyMed | 1 | 0 | 0 | Drugs and targets |
| LEVOFLOXACIN | CHEMBL5315124 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| TOSUFLOXACIN | CHEMBL273348 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| CIPROFLOXACIN | CHEMBL8 | Small molecule | Unknown | ClinicalTrials.gov | 3 | 3 | 3 | Drugs and targets |
Targets4
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| MMP1 | Interstitial collagenase | 1 | Matrix metalloproteinase-1 inhibitor | Approval | https://conductscience.org/library/genes/4312 | Drugs and targets |
| MMP13 | Collagenase 3 | 1 | Matrix metalloproteinase 13 inhibitor | Approval | https://conductscience.org/library/genes/4322 | Drugs and targets |
| MMP7 | Matrilysin | 1 | Matrix metalloproteinase 7 inhibitor | Approval | https://conductscience.org/library/genes/4316 | Drugs and targets |
| MMP8 | Neutrophil collagenase | 1 | Matrix metalloproteinase 8 inhibitor | Approval | https://conductscience.org/library/genes/4317 | Drugs and targets |
Trials5
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02016963 | An Open-label, Nonrandomized Study to Evaluate the Safety and Immunogenicity of Raxibacumab With Reinjection | Phase 2/3 | 20 | 2014-06-25 | Therapeutic Treatment of Inhalation Anthrax | RAXIBACUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT01670435 | Assessment of the Safety and Efficacy of Ciproxan-I.V. in Daily Clinical Practice - Analysis Results From a Post-marketing Surveillance | 3,274 | Infection | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT01690559 | Ciprofloxacin Special Drug Use Investigation - To Investigate the Safety and Efficacy in Patients With Ciprofloxacin iv Administration Without Dilution | 704 | Infection | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT02555059 | Special Drug Use Investigation of Ciproxan Injection in Pediatrics | 48 | Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT07478471 | Observational Study of Raxibacumab in Sporadic Cases of Systemic Anthrax | 10 | Infections, Bacterial | RAXIBACUMAB | Its record names the disease | ClinicalTrials.gov |
Comparisons in its trials0
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
None in this release.
Papers from its trials0
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
None in this release.
Data dates
The date of each source this release read.
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this disease from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0005119
GET https://conductscience.org/api/diseases/v1/MONDO_0005119/drugs