Disease · MONDO_0005647

anogenital human papillomavirus infection

6 sourcesdiseases-2026-09-18-0.1.0

Cite this record

ConductScience Library. anogenital human papillomavirus infection. Diseases, record MONDO_0005647. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0005647

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name: anogenital human papillomavirus infection; Open Targets
Open Targets ID: MONDO_0005647; Open Targets
Other names: Anogenital Human papilloma Virus Infectious Disease, Anogenital warts (disorder), Condylomata Acuminata, Genital warts, anogenital Human papilloma Virus infection, anogenital venereal wart, genital wart virus infectious disease, venereal wart; Open Targets
Disease Ontology: DOID:11168; Disease Ontology
MeSH: D003218; MeSH
NCI Thesaurus: C4820; NCI Thesaurus
Highest stage of its drugs: Approval, for 3 of its 15 drugs, from DailyMed, EMA Human Drugs, FDA and PMDA; Open Targets

Drugs15

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Drug	ChEMBL ID	Type	Open Targets' stage	Stage reported by	Reports	Of them trials	Trials shown here	Source
IMIQUIMOD	CHEMBL1282	Small molecule	Approval	EMA Human Drugs and PMDA	4	1	1	Drugs and targets
PODOFILOX	CHEMBL61	Small molecule	Approval	DailyMed	2	1	1	Drugs and targets
INTERFERON ALFA-2B	CHEMBL1201558	Protein	Approval	FDA	1	0	0	Drugs and targets
CYCLOPHOSPHAMIDE	CHEMBL1200796	Small molecule	Phase 3	ClinicalTrials.gov	1	1	1	Drugs and targets
INTERFERON GAMMA-1B	CHEMBL1201564	Protein	Phase 3	ClinicalTrials.gov	1	1	0	Drugs and targets
TUBERCULIN	CHEMBL2108161		Phase 3	ClinicalTrials.gov	1	1	1	Drugs and targets
AMMONIUM TRICHLOROTELLURATE	CHEMBL4584965	Small molecule	Phase 2	ClinicalTrials.gov	2	2	2	Drugs and targets
BERDAZIMER SODIUM	CHEMBL4298064	Small molecule	Phase 2	ClinicalTrials.gov	1	1	1	Drugs and targets
INGENOL MEBUTATE	CHEMBL1863513	Small molecule	Phase 2	ClinicalTrials.gov	1	1	1	Drugs and targets
RANPIRNASE	CHEMBL2108479	Enzyme	Phase 1/2	ClinicalTrials.gov	1	1	1	Drugs and targets

1 to 10 of 15

See all 15 drugs

Targets5

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

Target	Protein	Its drugs that act on it	Mechanisms	Highest stage of those drugs	Gene in Genes	Source
IFNAR1	Interferon alpha/beta receptor	2	Interferon alpha/beta receptor agonist	Approval	https://conductscience.org/library/genes/3454	Drugs and targets
IFNAR2	Interferon alpha/beta receptor	2	Interferon alpha/beta receptor agonist	Approval	https://conductscience.org/library/genes/3455	Drugs and targets
IFNGR1	Interferon gamma receptor	1	Interferon gamma receptor agonist	Phase 3	https://conductscience.org/library/genes/3459	Drugs and targets
IFNGR2	Interferon gamma receptor	1	Interferon gamma receptor agonist	Phase 3	https://conductscience.org/library/genes/3460	Drugs and targets
TLR7	Toll-like receptor 7	1	Toll-like receptor 7 agonist	Approval	https://conductscience.org/library/genes/51284	Drugs and targets

Trials13

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 2 more are not shown, since the checks do not confirm them.

Trial	Title	Phase	Participants	Results first posted	Conditions	Drugs	Linked by	Source
NCT03532776	Comparison Between Podofilox Topical Gel 0.5% and Allergan's Condylox® Gel 0.5% for External Anogenital Warts	Phase 3	466	2021-07-27	External Anogenital Warts	PODOFILOX	Open Targets' reading of its record	ClinicalTrials.gov
NCT02462187	Topical NVN1000 for the Treatment of External Genital and Perianal Warts	Phase 2	108	2023-04-05	Genital Warts, Perianal Warts	BERDAZIMER SODIUM	Its record names the disease	ClinicalTrials.gov
NCT06812065	Randomized Controlled Clinical Trial of Hyperthermia and Hydrogen Peroxide 3% in the Treatment of Cutaneous Warts	Not applicable	300		Warts	HYDROGEN PEROXIDE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00499967	Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts	Phase 1	202		Genital Warts	GS-9191	Its record names the disease	ClinicalTrials.gov
NCT00999986	Low Dose Cyclophosphamide Treats Genital Warts	Phase 3	104		Genital Wart	CYCLOPHOSPHAMIDE	Its record names the disease	ClinicalTrials.gov
NCT02535104	Safety and Efficacy Study of Topical Ranpirnase to Treat Genital Warts (HPV)	Phase 1/2	70		Condylomata Acuminata, Papillomavirus Infections, Sexually Transmitted Diseases	RANPIRNASE	Its record names the disease	ClinicalTrials.gov
NCT01943630	Safety and Efficacy Double Blind Vehicle Controlled Study of 15% AS101 Gel to Treat External Genital Warts	Phase 2	60		External Genital Warts	AMMONIUM TRICHLOROTELLURATE	Open Targets' reading of its record	ClinicalTrials.gov
NCT00761371	Imiquimod 5% Cream in the Treatment of External Genital or Perianal Warts in HIV+ Patients	Phase 4	52		Warts	IMIQUIMOD	Its record names the disease	ClinicalTrials.gov
NCT03153566	Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients	Phase 3	45		Genital Wart	TUBERCULIN	Its record names the disease	ClinicalTrials.gov
NCT00002327	The Safety and Effectiveness of Cidofovir in the Treatment of Venereal Warts in HIV-Infected Patients	Phase 1	40		HIV Infections, Condyloma Acuminata	CIDOFOVIR	Open Targets' reading of its record	ClinicalTrials.gov

1 to 10 of 13

See all 13 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

None in this release.

Papers from its trials7

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMID	Listed as	Trials listing it	Source
25273231	RESULT	1	PubMed
23336207	RESULT	1	PubMed
16973081	RESULT	1	PubMed
15897380	RESULT	1	PubMed
12807939	RESULT	1	PubMed
11238198	RESULT	1	PubMed
19466962	DERIVED	1	PubMed

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
Drug links and their checks, from Drugs and targets: 2026-09-18; Drugs and targets
ClinicalTrials.gov, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
PubMed, for the checks: 2026-11-06; PubMed
MeSH, for the checks: 2026-11-10; MeSH

Sources 6

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005647

GET https://conductscience.org/api/diseases/v1/MONDO_0005647/drugs

API reference For AI assistants