Disease · MONDO_0005701

chlamydia trachomatis infectious disease

6 sourcesdiseases-2026-09-18-0.1.0

Cite this record

ConductScience Library. chlamydia trachomatis infectious disease. Diseases, record MONDO_0005701. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0005701

On this page

Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name: chlamydia trachomatis infectious disease; Open Targets
Open Targets ID: MONDO_0005701; Open Targets
Other names: Chlamydia Infections, Chlamydia trachomatis caused disease or disorder, Chlamydia trachomatis disease or disorder, Chlamydial infection, chlamydial disease; Open Targets
Disease Ontology: DOID:11263; Disease Ontology
NCI Thesaurus: C34463; NCI Thesaurus
Highest stage of its drugs: Approval, for 1 of its 5 drugs, from TTD; Open Targets

Drugs5

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Drug	ChEMBL ID	Type	Open Targets' stage	Stage reported by	Reports	Of them trials	Trials shown here	Source
SILVER NITRATE	CHEMBL177367	Small molecule	Approval	TTD	1	0	0	Drugs and targets
AZITHROMYCIN	CHEMBL529	Small molecule	Phase 3	ClinicalTrials.gov	4	4	4	Drugs and targets
DOXYCYCLINE	CHEMBL1200699	Small molecule	Phase 3	ClinicalTrials.gov	2	2	2	Drugs and targets
RIFALAZIL	CHEMBL236297	Small molecule	Phase 2	ClinicalTrials.gov	1	1	1	Drugs and targets
TINIDAZOLE	CHEMBL1220	Small molecule	Phase 2	ClinicalTrials.gov	1	1	1	Drugs and targets

Targets4

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

Target	Protein	Its drugs that act on it	Mechanisms	Highest stage of those drugs	Gene in Genes	Source
MMP1	Interstitial collagenase	1	Matrix metalloproteinase-1 inhibitor	Phase 3	https://conductscience.org/library/genes/4312	Drugs and targets
MMP13	Collagenase 3	1	Matrix metalloproteinase 13 inhibitor	Phase 3	https://conductscience.org/library/genes/4322	Drugs and targets
MMP7	Matrilysin	1	Matrix metalloproteinase 7 inhibitor	Phase 3	https://conductscience.org/library/genes/4316	Drugs and targets
MMP8	Neutrophil collagenase	1	Matrix metalloproteinase 8 inhibitor	Phase 3	https://conductscience.org/library/genes/4317	Drugs and targets

Trials4

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

Trial	Title	Phase	Participants	Results first posted	Conditions	Drugs	Linked by	Source
NCT00980148	Treatment Failure of Chlamydial Infection in Males and Females in Youth Correctional Facilities	Phase 3	567	2015-03-18	Chlamydial Infection	AZITHROMYCIN, DOXYCYCLINE	Its record names the disease	ClinicalTrials.gov
NCT00322465	NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)	Phase 2	305	2011-08-17	Urethritis	AZITHROMYCIN, DOXYCYCLINE, TINIDAZOLE	Open Targets' reading of its record	ClinicalTrials.gov
NCT03249935	YCFM (Youth Correctional Facilities Males)	Phase 2	100	2019-10-28	Chlamydial Infection	AZITHROMYCIN	Its record names the disease	ClinicalTrials.gov
NCT01631201	Safety and Efficacy Study of Rifalazil for the Treatment of Chlamydia Trachomatis Infection in Women	Phase 2	82		Chlamydia Trachomatis Infection	AZITHROMYCIN, RIFALAZIL	Open Targets' reading of its record	ClinicalTrials.gov

Comparisons in its trials2

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

Comparison	Group 1, with the outcome	Group 2, with the outcome	Participants	Trial	Source
Azithromycin Arm vs Doxycycline Arm: serious adverse events	0 of 155	0 of 155	310	NCT00980148	Trial comparisons
Symptomatic vs Asymptomatic: Proportion of Participants Experiencing Treatment Failure After Treatment With Azithromycin for Uncomplicated Chlamydia Trachomatis (CT) in Males With and Without Urethral Symptoms	1 of 12	3 of 43	55	NCT03249935	Trial comparisons

Papers from its trials3

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMID	Listed as	Trials listing it	Source
21288838	RESULT	1	PubMed
26699167	DERIVED	1	PubMed
24798277	DERIVED	1	PubMed

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
Drug links and their checks, from Drugs and targets: 2026-09-18; Drugs and targets
ClinicalTrials.gov, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
PubMed, for the checks: 2026-11-06; PubMed
MeSH, for the checks: 2026-11-10; MeSH

Sources 6

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005701

GET https://conductscience.org/api/diseases/v1/MONDO_0005701/drugs

API reference For AI assistants