Drug · CHEMBL607
MEPERIDINE
7 sourcespipelines-2026-09-18-0.3.1
Cite this record
ConductScience Library. MEPERIDINE. Drugs and targets, record CHEMBL607. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL607
On this page
Drug
Names and IDs as ChEMBL gives them, through Open Targets.
- Other names
- IDS-NP-001, Isonipecaine, Meperidol, Pethanol, Pethidine, Pethidine dbl, Pethidineter, Petidina, Renaudin
- ChEMBL
Targets1
The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.
| Target | Protein | Mechanism | Action | Gene in Genes |
|---|---|---|---|---|
| OPRM1 | Mu-type opioid receptor | Mu opioid receptor agonist | AGONIST | https://conductscience.org/library/genes/4988 |
Source ChEMBL
Diseases5
The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Disease | Open Targets' stage | Stage reported by | Reports | Of them trials | Its drugs |
|---|---|---|---|---|---|
| Pain | Approval | ATC and TTD | 5 | 1 | https://conductscience.org/library/drugs?q=HP_0012531 |
| acute graft versus host disease | Phase 2 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0020546 |
| chronic graft versus host disease | Phase 2 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0020547 |
| graft versus host disease | Phase 2 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0013730 |
| postpartum depression | Phase 2/3 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0005929 |
Source Open Targets
Trials62
Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.
| Trial | Title | Phase | Participants | Results first posted | Named as | Linked by | Source |
|---|---|---|---|---|---|---|---|
| NCT02625181 | Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis | 27,034 | 2019-03-07 | meperidine | Its name | ClinicalTrials.gov | |
| NCT01741259 | A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus | 273 | 2017-10-25 | meperidine | Its name | ClinicalTrials.gov | |
| NCT01555671 | Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women | Phase 4 | 250 | 2021-09-30 | meperidine | Its name | ClinicalTrials.gov |
| NCT02494180 | A Non-inferiority Trial on Pain Relief During Oocyte Retrieval | Phase 4 | 170 | 2019-03-05 | pethidine | Its name | ClinicalTrials.gov |
| NCT01709422 | Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. | Phase 4 | 140 | 2013-08-27 | meperidine | Its name | ClinicalTrials.gov |
| NCT02486328 | The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System Endoscopy | Phase 4 | 103 | 2020-09-03 | meperidine | Its name | ClinicalTrials.gov |
| NCT01229527 | Comparison Between Two Different Dosages of Remifentanil During Colonoscopy | Phase 4 | 90 | 2012-02-01 | meperidine | Its name | ClinicalTrials.gov |
| NCT02027311 | Etomidate vs. Midazolam for Sedation During ERCP | Phase 4 | 63 | 2015-06-29 | meperidine | Its name | ClinicalTrials.gov |
| NCT05126459 | A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients | Phase 3 | 60 | 2024-10-02 | meperidine | Its name | ClinicalTrials.gov |
| NCT02684942 | Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy | Phase 4 | 40 | 2017-06-01 | meperidine | Its name | ClinicalTrials.gov |
1 to 10 of 62
See all 62 trialsComparisons in its trials18
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Meperidine PCEA vs Meperidine PCEA With Basal: Dysphoria | 0 of 127 | 0 of 129 | 256 | NCT01741259 | Trial comparisons |
| Meperidine PCEA vs Meperidine PCEA With Basal: Pruritus | 20 of 127 | 10 of 129 | 256 | NCT01741259 | Trial comparisons |
| Meperidine PCEA vs Meperidine PCEA With Basal: Inadequate Analgesia | 7 of 127 | 3 of 129 | 256 | NCT01741259 | Trial comparisons |
| Meperidine PCEA vs Meperidine PCEA With Basal: Adverse Outcomes | 0 of 127 | 0 of 129 | 256 | NCT01741259 | Trial comparisons |
| Meperidine PCEA vs Meperidine PCEA With Basal: Nausea and Vomiting | 1 of 127 | 3 of 129 | 256 | NCT01741259 | Trial comparisons |
| Meperidine PCEA vs Meperidine PCEA With Basal: deaths from any cause | 0 of 127 | 0 of 129 | 256 | NCT01741259 | Trial comparisons |
| Meperidine PCEA vs Meperidine PCEA With Basal: serious adverse events | 0 of 127 | 0 of 129 | 256 | NCT01741259 | Trial comparisons |
| Study Group vs Control Group: serious adverse events | 0 of 105 | 0 of 100 | 205 | NCT01555671 | Trial comparisons |
| A: Intravenous Fentanyl, Midazolam vs B: Intravenous Pethidine, Diazepam: deaths from any cause | 0 of 85 | 0 of 85 | 170 | NCT02494180 | Trial comparisons |
| A: Intravenous Fentanyl, Midazolam vs B: Intravenous Pethidine, Diazepam: serious adverse events | 0 of 85 | 0 of 85 | 170 | NCT02494180 | Trial comparisons |
1 to 10 of 18
See all 18 comparisons in its trialsPapers from its trials57
The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Tests in its trials1
The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.
| Test | Trials naming it as an outcome | As a primary outcome |
|---|---|---|
| Symbol Coding | 1 | 1 |
Source ConductCognition
Data dates
The date of each source this release read.
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this drug from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL607
GET https://conductscience.org/api/drugs/v1/CHEMBL607/trials?page=2