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Paper · 16636133

A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.

McDevitt MA and 14 others. J Exp Med, 2006. Cited by 108 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. Papers, record 16636133. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16636133

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.
PubMed
Journal
J Exp Med
PubMed
Year
2006
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
108
iCite
Relative citation ratio, by iCite
2.65
iCite
Revised in PubMed
2021-10-20
PubMed

Authors15

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1McDevitt MAMichael A
2Xie JJianlin
3Ganapathy-Kanniappan SShanmugasundaram
4Shanmugasundaram GGanapathy
5Griffith JJason
6Liu AAihua
7McDonald CCourtney
8Thuma PPhilip
9Gordeuk VRVictor R
10Metz CNChristine N

1 to 10 of 15Source PubMed

See all 15 authors

Topics22

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AnemiaMajor topic
ErythropoiesisMajor topic
Macrophage Migration-Inhibitory FactorsMajor topic
MalariaMajor topic
Plasmodium chabaudiMajor topic
Alleles
Animals
Cell Differentiation
Cells, Cultured
Cytokines
Erythroid Precursor Cells
Gene Expression Regulation
Hemeproteins
Humans
Immunity, Innate
Intramolecular Oxidoreductases
Macrophages
Mice
Mice, Inbred BALB C
Mice, Knockout
Polymorphism, Genetic
Quantitative Trait Loci

Source PubMed

Grants11

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
AR49610NIAMS NIH HHSUnited StatesR01AR049610PubMed and NIHNIH RePORTER
UH1-HL03679-07NHLBI NIH HHSUnited StatesUH1HL036790PubMedNIH RePORTER
R01 AR049610NIAMS NIH HHSUnited StatesR01AR049610PubMed and NIHNIH RePORTER
2R01-AI042310NIAID NIH HHSUnited StatesR01AI042310PubMed and NIHNIH RePORTER
M01-RR10284NCRR NIH HHSUnited StatesM01RR010284PubMed and NIHNIH RePORTER
M01 RR010284NCRR NIH HHSUnited StatesM01RR010284PubMed and NIHNIH RePORTER
R01 AI051306NIAID NIH HHSUnited StatesR01AI051306PubMed and NIHNIH RePORTER
R01 AI042310NIAID NIH HHSUnited StatesR01AI042310PubMed and NIHNIH RePORTER
1R01-AI44587-05NIAID NIH HHSUnited StatesR01AI445870PubMedNIH RePORTER
UH1 HL003679NHLBI NIH HHSUnited StatesUH1HL003679PubMed and NIHNIH RePORTER

1 to 10 of 11

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Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Erratum in25,941,322A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.https://conductscience.org/library/papers/25941322

Source PubMed

References67

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,978,116Hemozoin-inducible proinflammatory events in vivo: potential role in malaria infection.J Immunol2004https://conductscience.org/library/papers/14978116PubMed
210,474,636Anaemia in acute, Plasmodium falciparum malaria in children from Orissa state, India.Ann Trop Med Parasitol1999https://conductscience.org/library/papers/10474636PubMed
310,466,119Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes.Parasitology1999https://conductscience.org/library/papers/10466119PubMed
48,063,391Blood transfusion alters the course and outcome of Plasmodium chabaudi AS infection in mice.Infect Immun1994https://conductscience.org/library/papers/8063391PubMed
512,070,782A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis.Genes Immun2002https://conductscience.org/library/papers/12070782PubMed
61,582,489Malaria pigment.Exp Parasitol1992https://conductscience.org/library/papers/1582489PubMed
711,756,671Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response.Proc Natl Acad Sci U S A2002https://conductscience.org/library/papers/11756671PubMed
89,136,961Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria.Br J Haematol1997https://conductscience.org/library/papers/9136961PubMed
912,224,573Anemia in parasite- and recombinant protein-immunized aotus monkeys infected with Plasmodium falciparum.Am J Trop Med Hyg2002https://conductscience.org/library/papers/12224573PubMed
1015,630,134Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin.J Exp Med2005https://conductscience.org/library/papers/15630134PubMed

1 to 10 of 67

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Cited by80

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 108 citations.

PMIDTitleJournalYearIn PapersSource
41,171,200Emerging Role of Splenic Macrophage in Malaria Pathogenesis and Immunity.Immun Inflamm Dis2025https://conductscience.org/library/papers/41171200PubMed
40,980,010Malaria and dyserythropoiesis: a mini review.Front Cell Infect Microbiol2025https://conductscience.org/library/papers/40980010PubMed
36,750,316Immune Mechanisms in Inflammatory Anemia.Annu Rev Immunol2023https://conductscience.org/library/papers/36750316PubMed
36,361,552Erythropoiesis and Malaria, a Multifaceted Interplay.Int J Mol Sci2022https://conductscience.org/library/papers/36361552PubMed
36,146,602Mouse Models for Unravelling Immunology of Blood Stage Malaria.Vaccines (Basel)2022https://conductscience.org/library/papers/36146602PubMed
36,093,199Macrophage migration inhibitory factor contributes to immunopathogenesis during Plasmodium yoelii 17XL infection.Front Cell Infect Microbiol2022https://conductscience.org/library/papers/36093199PubMed
35,464,430The Role of MIF and IL-10 as Molecular Yin-Yang in the Modulation of the Host Immune Microenvironment During Infections: African Trypanosome Infections as a Paradigm.Front Immunol2022https://conductscience.org/library/papers/35464430PubMed
34,662,363Macrophage migration inhibitory factor in Nodding syndrome.PLoS Negl Trop Dis2021https://conductscience.org/library/papers/34662363PubMed
33,604,547Low expression Macrophage Migration Inhibitory Factor (MIF) alleles and tuberculosis in HIV infected South Africans.Cytokine X2019https://conductscience.org/library/papers/33604547PubMed
32,244,916Role of Host and Parasite MIF Cytokines during Leishmania Infection.Trop Med Infect Dis2020https://conductscience.org/library/papers/32244916PubMed

1 to 10 of 80

See all 80 cited by

Genes9

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
EPO2,056PubTator's text mininghttps://conductscience.org/library/genes/2056NCBI Gene
IFNG3,458PubTator's text mininghttps://conductscience.org/library/genes/3458NCBI Gene
IL103,586PubTator's text mininghttps://conductscience.org/library/genes/3586NCBI Gene
IL12B3,593PubTator's text mininghttps://conductscience.org/library/genes/3593NCBI Gene
IL1B3,553PubTator's text mininghttps://conductscience.org/library/genes/3553NCBI Gene
MAPK141,432PubTator's text mininghttps://conductscience.org/library/genes/1432NCBI Gene
MIF4,282PubTator's text mininghttps://conductscience.org/library/genes/4282NCBI Gene
TLR954,106PubTator's text mininghttps://conductscience.org/library/genes/54106NCBI Gene
TNF7,124PubTator's text mininghttps://conductscience.org/library/genes/7124NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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