Paper · 19412331

Myostatin in the pathophysiology of skeletal muscle.

Carnac G and 2 others. Curr Genomics, 2007. Cited by 86 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Myostatin in the pathophysiology of skeletal muscle. Papers, record 19412331. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/19412331

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Myostatin in the pathophysiology of skeletal muscle.; PubMed
Journal: Curr Genomics; PubMed
Year: 2007; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/19412331/; PubMed
DOI: https://doi.org/10.2174/138920207783591672; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2647158/; PubMed
The journal: https://conductscience.org/library/journal-index/100960527; PubMed
Citations, by iCite: 86; iCite
Relative citation ratio, by iCite: 2.3; iCite
Revised in PubMed: 2021-10-20; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Carnac G	Gilles
2	Vernus B	Barbara
3	Bonnieu A	Anne

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References76

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	12,559,968	Inhibition of myostatin in adult mice increases skeletal muscle mass and strength.	Biochem Biophys Res Commun	2003	https://conductscience.org/library/papers/12559968	PubMed
2	12,717,734	Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene.	Genesis	2003	https://conductscience.org/library/papers/12717734	PubMed
3	12,618,358	Myostatin-deficient mice lose more skeletal muscle mass than wild-type controls during hindlimb suspension.	Am J Physiol Endocrinol Metab	2003	https://conductscience.org/library/papers/12618358	PubMed
4	16,110,474	Myostatin auto-regulates its expression by feedback loop through Smad7 dependent mechanism.	J Cell Physiol	2006	https://conductscience.org/library/papers/16110474	PubMed
5	10,362,012	Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct.	J Cell Physiol	1999	https://conductscience.org/library/papers/10362012	PubMed
6	9,139,826	Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member.	Nature	1997	https://conductscience.org/library/papers/9139826	PubMed
7	9,288,100	A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle.	Nat Genet	1997	https://conductscience.org/library/papers/9288100	PubMed
8	7,885,475	Multiple defects and perinatal death in mice deficient in follistatin.	Nature	1995	https://conductscience.org/library/papers/7885475	PubMed
9	17,689,926	Regulation of myostatin signaling by c-Jun N-terminal kinase in C2C12 cells.	Cell Signal	2007	https://conductscience.org/library/papers/17689926	PubMed
10	12,447,939	Loss of myostatin attenuates severity of muscular dystrophy in mdx mice.	Ann Neurol	2002	https://conductscience.org/library/papers/12447939	PubMed

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Cited by62

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 86 citations.

PMID	Title	Journal	Year	In Papers	Source
42,545,477	Mechanical loading vs. hypoxic stress: differential regulation of circulating irisin, myostatin, and HIF-1α following resistance training in young adults with overweight.	Eur J Appl Physiol	2026	https://conductscience.org/library/papers/42545477	PubMed
42,337,614	Accumulation of membrane repair-associated proteins and mature myostatin are novel markers of muscle pathophysiology in Pompe disease.	Acta Neuropathol Commun	2026	https://conductscience.org/library/papers/42337614	PubMed
42,298,331	Creatine/Creatinine Ratio and Myostatin as Biomarkers to Monitor Muscle Function in Duchenne Muscular Dystrophy Patients.	J Cachexia Sarcopenia Muscle	2026	https://conductscience.org/library/papers/42298331	PubMed
42,123,420	Myostatin Research: From Molecular Understanding to Clinical Translation for Musculoskeletal and Metabolic Disorders.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42123420	PubMed
41,975,983	Follicle-Stimulating Hormone in Peripheral Metabolism: Novel Insights into Growth Regulation and Potential Applications in Boar Production.	Animals (Basel)	2026	https://conductscience.org/library/papers/41975983	PubMed
41,907,069	Harnessing myostatin pleiotropy for multitrait improvement via precision gene editing.	Front Genome Ed	2026	https://conductscience.org/library/papers/41907069	PubMed
41,731,743	A High Dose of Short-term Intraperitoneal D-galactose-induced Aging Process in Male Rats.	Ann Afr Med	2026	https://conductscience.org/library/papers/41731743	PubMed
41,002,673	Role of Myokines on the Bone Metabolism of Craniofacial Region: A Scoping Review.	Dent J (Basel)	2025	https://conductscience.org/library/papers/41002673	PubMed
40,959,925	Radiation-induced impairment of skeletal muscle regeneration.	Radiol Oncol	2025	https://conductscience.org/library/papers/40959925	PubMed
40,944,148	Muscle Biomarkers as Molecular Signatures for Early Detection and Monitoring of Muscle Health in Aging.	Nutrients	2025	https://conductscience.org/library/papers/40944148	PubMed

1 to 10 of 62

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Genes15

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
AKT1	207	PubTator's text mining	https://conductscience.org/library/genes/207	NCBI Gene
CCND1	595	PubTator's text mining	https://conductscience.org/library/genes/595	NCBI Gene
CDK2	1,017	PubTator's text mining	https://conductscience.org/library/genes/1017	NCBI Gene
CDK4	1,019	PubTator's text mining	https://conductscience.org/library/genes/1019	NCBI Gene
CDKN1A	1,026	PubTator's text mining	https://conductscience.org/library/genes/1026	NCBI Gene
DCN	1,634	PubTator's text mining	https://conductscience.org/library/genes/1634	NCBI Gene
FST	10,468	PubTator's text mining	https://conductscience.org/library/genes/10468	NCBI Gene
FSTL3	10,272	PubTator's text mining	https://conductscience.org/library/genes/10272	NCBI Gene
GGH	8,836	PubTator's text mining	https://conductscience.org/library/genes/8836	NCBI Gene
GSK3B	2,932	PubTator's text mining	https://conductscience.org/library/genes/2932	NCBI Gene

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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