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Paper · 35138907

A functional genomic approach to actionable gene fusions for precision oncology.

Li J and 36 others. Sci Adv, 2022. Cited by 18 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A functional genomic approach to actionable gene fusions for precision oncology. Papers, record 35138907. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/35138907

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A functional genomic approach to actionable gene fusions for precision oncology.
PubMed
Journal
Sci Adv
PubMed
Year
2022
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
18
iCite
Relative citation ratio, by iCite
1.13
iCite
Revised in PubMed
2024-09-23
PubMed

Authors37

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Li JJunhttps://orcid.org/0000-0002-1171-7141
2Lu HHengyuhttps://orcid.org/0000-0003-1093-9364
3Ng PKPatrick Kwok-Shinghttps://orcid.org/0000-0003-0364-7443
4Pantazi AAngelikihttps://orcid.org/0000-0002-7416-3270
5Ip CKMCarman Ka Manhttps://orcid.org/0000-0002-6672-5982
6Jeong KJKang Jin
7Amador BBianca
8Tran RRichardhttps://orcid.org/0000-0001-8403-1311
9Tsang YHYiu Huenhttps://orcid.org/0000-0002-0895-6854
10Yang LLixinghttps://orcid.org/0000-0001-9618-2117

1 to 10 of 37Source PubMed

See all 37 authors

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
NeoplasmsMajor topic
Gene Fusion
Genome
Genomics
Humans
Precision Medicine

Source PubMed

Grants9

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 CA016672NCI NIH HHSUnited StatesP30CA016672PubMed and NIHNIH RePORTER
U01 CA253472NCI NIH HHSUnited StatesU01CA253472PubMedNIH RePORTER
P50 CA217685NCI NIH HHSUnited StatesP50CA217685PubMedNIH RePORTER
U24 CA144025NCI NIH HHSUnited StatesU24CA144025PubMedNIH RePORTER
P30 CA125123NCI NIH HHSUnited StatesP30CA125123PubMedNIH RePORTER
U24 CA209851NCI NIH HHSUnited StatesU24CA209851PubMed and NIHNIH RePORTER
P50 CA098258NCI NIH HHSUnited StatesP50CA098258PubMedNIH RePORTER
U01 CA168394NCI NIH HHSUnited StatesU01CA168394PubMedNIH RePORTER
U01 CA217842NCI NIH HHSUnited StatesU01CA217842PubMedNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References42

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
129,625,053Comprehensive Characterization of Cancer Driver Genes and Mutations.Cell2018https://conductscience.org/library/papers/29625053PubMed
24,126,434Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.Nature1973https://conductscience.org/library/papers/4126434PubMed
312,798,140Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures.Methods2003https://conductscience.org/library/papers/12798140PubMed
417,133,113Ba/F3 cells and their use in kinase drug discovery.Curr Opin Oncol2007https://conductscience.org/library/papers/17133113PubMed
529,100,075Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas.Cell2017https://conductscience.org/library/papers/29100075PubMed
622,614,325ALKoma: a cancer subtype with a shared target.Cancer Discov2012https://conductscience.org/library/papers/22614325PubMed
724,206,917Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment.Chin J Cancer2013https://conductscience.org/library/papers/24206917PubMed
823,558,953Identification of targetable FGFR gene fusions in diverse cancers.Cancer Discov2013https://conductscience.org/library/papers/23558953PubMed
925,204,415The landscape of kinase fusions in cancer.Nat Commun2014https://conductscience.org/library/papers/25204415PubMed
1016,254,181Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.Science2005https://conductscience.org/library/papers/16254181PubMed

1 to 10 of 42

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Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 18 citations.

PMIDTitleJournalYearIn PapersSource
42,199,442Research advances in the application of microfluidic chip technology for rapid detection of antibiotic-resistant bacteria.Front Cell Infect Microbiol2026https://conductscience.org/library/papers/42199442PubMed
42,098,956Gene fusions in melanocytic lesions: an updated comprehensive review.J Pathol Transl Med2026https://conductscience.org/library/papers/42098956PubMed
42,021,362Fusion oncogenes in cancer: organoid models and novel therapeutic approaches.BMC Biol2026https://conductscience.org/library/papers/42021362PubMed
40,319,462Multiomic profiling of glioblastoma metabolic lesions reveals complex intratumoral genomic evolution and dipeptidase-1-driven vascular proliferation.Neuro Oncol2025https://conductscience.org/library/papers/40319462PubMed
40,223,139Oncogenic gene fusions in cancer: from biology to therapy.Signal Transduct Target Ther2025https://conductscience.org/library/papers/40223139PubMed
39,906,487Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.Front Mol Biosci2024https://conductscience.org/library/papers/39906487PubMed
39,513,959Utilizing Patient-Derived Xenografts to Model Precision Oncology for Biliary Tract Cancer.Clin Cancer Res2025https://conductscience.org/library/papers/39513959PubMed
39,297,878Clinical bioinformatics desiderata for molecular tumor boards.Brief Bioinform2024https://conductscience.org/library/papers/39297878PubMed
38,986,029Fusion Challenges in Solid Tumors: Shaping the Landscape of Cancer Care in Precision Medicine.JCO Precis Oncol2024https://conductscience.org/library/papers/38986029PubMed
38,833,619Oncofusions - shaping cancer care.Oncologist2025https://conductscience.org/library/papers/38833619PubMed

1 to 10 of 16

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Genes43

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ABL125PubTator's text mininghttps://conductscience.org/library/genes/25NCBI Gene
AKT310,000PubTator's text mininghttps://conductscience.org/library/genes/10000NCBI Gene
ALK238PubTator's text mininghttps://conductscience.org/library/genes/238NCBI Gene
BAIAP2L155,971PubTator's text mininghttps://conductscience.org/library/genes/55971NCBI Gene
BICC180,114PubTator's text mininghttps://conductscience.org/library/genes/80114NCBI Gene
BRAF673PubTator's text mininghttps://conductscience.org/library/genes/673NCBI Gene
EGFR1,956PubTator's text mininghttps://conductscience.org/library/genes/1956NCBI Gene
ELAVL31,995PubTator's text mininghttps://conductscience.org/library/genes/1995NCBI Gene
EML427,436PubTator's text mininghttps://conductscience.org/library/genes/27436NCBI Gene
FANCC2,176PubTator's text mininghttps://conductscience.org/library/genes/2176NCBI Gene

1 to 10 of 43

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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