Paper · 36900367
Evolution of the Targeted Therapy Landscape for Cholangiocarcinoma: Is Cholangiocarcinoma the 'NSCLC' of GI Oncology?
Gupta A and 2 others. Cancers (Basel), 2023. Cited by 26 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Evolution of the Targeted Therapy Landscape for Cholangiocarcinoma: Is Cholangiocarcinoma the 'NSCLC' of GI Oncology? Papers, record 36900367. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36900367
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Evolution of the Targeted Therapy Landscape for Cholangiocarcinoma: Is Cholangiocarcinoma the 'NSCLC' of GI Oncology?
- PubMed
Topics0
NLM's MeSH indexing of the paper, its major topics first.
None in this release.
Grants4
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| U10 CA180888 | NCI NIH HHS | United States | U10CA180888 | PubMed and NIH | NIH RePORTER |
| UG1 CA233198 | NCI NIH HHS | United States | UG1CA233198 | PubMed and NIH | NIH RePORTER |
| 5U01CA180888-08 | HHS | United States | U01CA180888 | PubMed | NIH RePORTER |
| 5UG1CA233198-05 | HHS | United States | UG1CA233198 | PubMed and NIH | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References123
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 27,870,574 | Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study. | J Clin Oncol | 2017 | https://conductscience.org/library/papers/27870574 | PubMed |
| 2 | 28,441,383 | The oral VEGF receptor tyrosine kinase inhibitor pazopanib in combination with the MEK inhibitor trametinib in advanced cholangiocarcinoma. | Br J Cancer | 2017 | https://conductscience.org/library/papers/28441383 | PubMed |
| 3 | 32,416,072 | Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study. | Lancet Oncol | 2020 | https://conductscience.org/library/papers/32416072 | PubMed |
| 4 | 25,744,437 | BRAF V600E mutation-specific antibody: A review. | Semin Diagn Pathol | 2015 | https://conductscience.org/library/papers/25744437 | PubMed |
| 5 | 23,251,089 | Dabrafenib and its potential for the treatment of metastatic melanoma. | Drug Des Devel Ther | 2012 | https://conductscience.org/library/papers/23251089 | PubMed |
| 6 | 27,095,655 | Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA). | Nat Rev Gastroenterol Hepatol | 2016 | https://conductscience.org/library/papers/27095655 | PubMed |
| 7 | 28,183,697 | Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1). | Cancer Discov | 2017 | https://conductscience.org/library/papers/28183697 | PubMed |
| 8 | 22,356,324 | Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. | N Engl J Med | 2012 | https://conductscience.org/library/papers/22356324 | PubMed |
| 9 | 25,526,346 | Mutational landscape of intrahepatic cholangiocarcinoma. | Nat Commun | 2014 | https://conductscience.org/library/papers/25526346 | PubMed |
| 10 | 30,031,797 | Molecular targeted therapy: Treating cancer with specificity. | Eur J Pharmacol | 2018 | https://conductscience.org/library/papers/30031797 | PubMed |
1 to 10 of 123
See all 123 referencesCited by12
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 26 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,773,262 | Fibroblast Growth Factor Receptor (FGFR) Inhibitors for the Treatment of Cholangiocarcinoma: Key Therapeutic Developments and Knowledge Gaps. | Drug Des Devel Ther | 2026 | https://conductscience.org/library/papers/41773262 | PubMed |
| 41,309,533 | Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges. | Signal Transduct Target Ther | 2025 | https://conductscience.org/library/papers/41309533 | PubMed |
| 40,870,997 | In Vitro and In Vivo Evaluation of Alectinib-Loaded Dendrimer Nanoparticles as a Drug Delivery System for Non-Small Cell Lung Carcinoma. | Pharmaceutics | 2025 | https://conductscience.org/library/papers/40870997 | PubMed |
| 40,281,353 | Genomic landscape of biliary tract cancer and corresponding targeted treatment strategies. | Int J Clin Oncol | 2025 | https://conductscience.org/library/papers/40281353 | PubMed |
| 40,001,320 | A Comprehensive Analysis of FGF/FGFR Signaling Alteration in NSCLC: Implications in Prognosis and Microenvironment. | Thorac Cancer | 2025 | https://conductscience.org/library/papers/40001320 | PubMed |
| 38,672,619 | Recent Advances in Pathology of Intrahepatic Cholangiocarcinoma. | Cancers (Basel) | 2024 | https://conductscience.org/library/papers/38672619 | PubMed |
| 38,645,422 | Navigating uncharted territory: a case report and literature review on the remarkable response to personalized crizotinib containing combinational therapy in a pazopanib refractory patient with novel alterations. | Ther Adv Med Oncol | 2024 | https://conductscience.org/library/papers/38645422 | PubMed |
| 38,612,518 | ETV6::NTRK3 Fusion-Positive Wild-Type Gastrointestinal Stromal Tumor (GIST) with Abundant Lymphoid Infiltration (TILs and Tertiary Lymphoid Structures): A Report on a New Case with Therapeutic Implications and a Literature Review. | Int J Mol Sci | 2024 | https://conductscience.org/library/papers/38612518 | PubMed |
| 37,894,467 | Don't Judge a Book by Its Cover: The Role of Statins in Liver Cancer. | Cancers (Basel) | 2023 | https://conductscience.org/library/papers/37894467 | PubMed |
| 37,834,032 | A Novel Mouse Model of Intrahepatic Cholangiocarcinoma Induced by Azoxymethane. | Int J Mol Sci | 2023 | https://conductscience.org/library/papers/37834032 | PubMed |
1 to 10 of 12
See all 12 cited byGenes32
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AKT1 | 207 | PubTator's text mining | https://conductscience.org/library/genes/207 | NCBI Gene |
| ALK | 238 | PubTator's text mining | https://conductscience.org/library/genes/238 | NCBI Gene |
| ATHS | 470 | PubTator's text mining | https://conductscience.org/library/genes/470 | NCBI Gene |
| BRAF | 673 | PubTator's text mining | https://conductscience.org/library/genes/673 | NCBI Gene |
| BRCA1 | 672 | PubTator's text mining | https://conductscience.org/library/genes/672 | NCBI Gene |
| BRCA2 | 675 | PubTator's text mining | https://conductscience.org/library/genes/675 | NCBI Gene |
| CD274 | 29,126 | PubTator's text mining | https://conductscience.org/library/genes/29126 | NCBI Gene |
| CD8A | 925 | PubTator's text mining | https://conductscience.org/library/genes/925 | NCBI Gene |
| CTLA4 | 1,493 | PubTator's text mining | https://conductscience.org/library/genes/1493 | NCBI Gene |
| EGFR | 1,956 | PubTator's text mining | https://conductscience.org/library/genes/1956 | NCBI Gene |
1 to 10 of 32
See all 32 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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