Paper · 36980232
Heparanase Modulates Chromatin Accessibility.
Li H and 7 others. Cells, 2023. Cited by 5 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Heparanase Modulates Chromatin Accessibility. Papers, record 36980232. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36980232
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics7
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Chromatin | Major topic |
| Fibroblasts | Major topic |
| Mice | |
| Animals | |
| Heparan Sulfate | |
| Glucuronidase | |
| Heparanase |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References47
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 2,944,884 | Transport of heparan sulfate into the nuclei of hepatocytes. | J Biol Chem | 1986 | https://conductscience.org/library/papers/2944884 | PubMed |
| 2 | 33,372,561 | Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium. | Curr Eye Res | 2021 | https://conductscience.org/library/papers/33372561 | PubMed |
| 3 | 33,748,723 | Dissociation of DNA damage sensing by endoglycosidase HPSE. | iScience | 2021 | https://conductscience.org/library/papers/33748723 | PubMed |
| 4 | 21,490,396 | Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice. | J Clin Invest | 2011 | https://conductscience.org/library/papers/21490396 | PubMed |
| 5 | 34,238,359 | The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes. | Clin Epigenetics | 2021 | https://conductscience.org/library/papers/34238359 | PubMed |
| 6 | 24,119,843 | Super-enhancers in the control of cell identity and disease. | Cell | 2013 | https://conductscience.org/library/papers/24119843 | PubMed |
| 7 | 19,360,105 | Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases. | PLoS One | 2009 | https://conductscience.org/library/papers/19360105 | PubMed |
| 8 | 34,693,552 | Heparanase is a regulator of natural killer cell activation and cytotoxicity. | J Leukoc Biol | 2022 | https://conductscience.org/library/papers/34693552 | PubMed |
| 9 | 29,431,512 | Heparanase Is a Critical Regulator of Mitotic Spindles Required for Maintaining Chromosome Stability. | DNA Cell Biol | 2018 | https://conductscience.org/library/papers/29431512 | PubMed |
| 10 | 22,771,948 | The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes. | Transcription | 2012 | https://conductscience.org/library/papers/22771948 | PubMed |
1 to 10 of 47
See all 47 referencesCited by3
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 5 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,091,243 | Heparanase2 inhibits the growth of gallbladder cancer by regulating the VEGF/VEGFR pathway. | Discov Oncol | 2025 | https://conductscience.org/library/papers/41091243 | PubMed |
| 40,899,692 | The Pathophysiological Functions of Heparanases: From Evolution, Structural and Tissue-Specific Perspectives. | FASEB J | 2025 | https://conductscience.org/library/papers/40899692 | PubMed |
| 37,547,889 | Heparanase-A single protein with multiple enzymatic and nonenzymatic functions. | Proteoglycan Res | 2023 | https://conductscience.org/library/papers/37547889 | PubMed |
Genes8
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CCND1 | 595 | PubTator's text mining | https://conductscience.org/library/genes/595 | NCBI Gene |
| CTSL | 1,514 | PubTator's text mining | https://conductscience.org/library/genes/1514 | NCBI Gene |
| DEFB1 | 1,672 | PubTator's text mining | https://conductscience.org/library/genes/1672 | NCBI Gene |
| DEFB4A | 1,673 | PubTator's text mining | https://conductscience.org/library/genes/1673 | NCBI Gene |
| HPSE | 10,855 | PubTator's text mining | https://conductscience.org/library/genes/10855 | NCBI Gene |
| MMP9 | 4,318 | PubTator's text mining | https://conductscience.org/library/genes/4318 | NCBI Gene |
| PTEN | 5,728 | PubTator's text mining | https://conductscience.org/library/genes/5728 | NCBI Gene |
| SDC1 | 6,382 | PubTator's text mining | https://conductscience.org/library/genes/6382 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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