Paper · 41724111
Quantifying rate-limiting genetic variation in breast and ovarian tumourigenesis.
Houlahan KE and 10 others. EBioMedicine, 2026. Cited by 0 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Quantifying rate-limiting genetic variation in breast and ovarian tumourigenesis. Papers, record 41724111. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41724111
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Ovarian Neoplasms | Major topic |
| Breast Neoplasms | Major topic |
| Genetic Variation | Major topic |
| Carcinogenesis | Major topic |
| Humans | |
| Female | |
| DNA Copy Number Variations | |
| Mutation | |
| Polymorphism, Single Nucleotide | |
| Germ-Line Mutation | |
| BRCA2 Protein | |
| Genetic Predisposition to Disease |
Source PubMed
Grants2
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| P30 CA008748 | NCI NIH HHS | United States | P30CA008748 | PubMed | NIH RePORTER |
| R35 GM138113 | NIGMS NIH HHS | United States | R35GM138113 | PubMed | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References68
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 32,025,013 | The evolutionary history of 2,658 cancers. | Nature | 2020 | https://conductscience.org/library/papers/32025013 | PubMed |
| 2 | 31,645,730 | The landscape of somatic mutation in normal colorectal epithelial cells. | Nature | 2019 | https://conductscience.org/library/papers/31645730 | PubMed |
| 3 | 25,535,351 | Only three driver gene mutations are required for the development of lung and colorectal cancers. | Proc Natl Acad Sci U S A | 2015 | https://conductscience.org/library/papers/25535351 | PubMed |
| 4 | 30,154,431 | Evaluating intrinsic and non-intrinsic cancer risk factors. | Nat Commun | 2018 | https://conductscience.org/library/papers/30154431 | PubMed |
| 5 | 30,300,578 | Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers. | Cancer Cell | 2018 | https://conductscience.org/library/papers/30300578 | PubMed |
| 6 | 23,540,688 | Lessons from the cancer genome. | Cell | 2013 | https://conductscience.org/library/papers/23540688 | PubMed |
| 7 | 37,673,861 | The mutational landscape of the adult healthy parous and nulliparous human breast. | Nat Commun | 2023 | https://conductscience.org/library/papers/37673861 | PubMed |
| 8 | 28,067,867 | Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories. | Nat Commun | 2017 | https://conductscience.org/library/papers/28067867 | PubMed |
| 9 | 22,528,874 | Signification of Hypermethylated in Cancer 1 (HIC1) as Tumor Suppressor Gene in Tumor Progression. | Cancer Microenviron | 2012 | https://conductscience.org/library/papers/22528874 | PubMed |
| 10 | 39,779,850 | Complex rearrangements fuel ER+ and HER2+ breast tumours. | Nature | 2025 | https://conductscience.org/library/papers/39779850 | PubMed |
1 to 10 of 68
See all 68 referencesCited by0
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 0 citations.
None in this release.
Genes28
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| ATM | 472 | PubTator's text mining | https://conductscience.org/library/genes/472 | NCBI Gene |
| ATP8B1 | 5,205 | PubTator's text mining | https://conductscience.org/library/genes/5205 | NCBI Gene |
| ATR | 545 | PubTator's text mining | https://conductscience.org/library/genes/545 | NCBI Gene |
| BARD1 | 580 | PubTator's text mining | https://conductscience.org/library/genes/580 | NCBI Gene |
| BRCA1 | 672 | PubTator's text mining | https://conductscience.org/library/genes/672 | NCBI Gene |
| BRCA2 | 675 | PubTator's text mining | https://conductscience.org/library/genes/675 | NCBI Gene |
| CBFB | 865 | PubTator's text mining | https://conductscience.org/library/genes/865 | NCBI Gene |
| CDH1 | 999 | PubTator's text mining | https://conductscience.org/library/genes/999 | NCBI Gene |
| CHEK2 | 11,200 | PubTator's text mining | https://conductscience.org/library/genes/11200 | NCBI Gene |
| COL11A2 | 1,302 | PubTator's text mining | https://conductscience.org/library/genes/1302 | NCBI Gene |
1 to 10 of 28
See all 28 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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Read this paper from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/papers/v1/41724111
GET https://conductscience.org/api/papers/v1/41724111/references?page=2