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Paper · 42430785

A graph retrieval-augmented generation pipeline for systematic drug target discovery: validation and application to ocular neovascularization.

Mun Y and 6 others. Brief Bioinform, 2026. Cited by 0 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A graph retrieval-augmented generation pipeline for systematic drug target discovery: validation and application to ocular neovascularization. Papers, record 42430785. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42430785

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A graph retrieval-augmented generation pipeline for systematic drug target discovery: validation and application to ocular neovascularization.
PubMed
Journal
Brief Bioinform
PubMed
Year
2026
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
0
iCite
Revised in PubMed
2026-08-13
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Mun YYongseok
2Ma DJDae Joong
3Kim HKHa Kyoung
4Joo KKwangsic
5Park SJSang Jun
6Woo SJSe Joonhttps://orcid.org/0000-0003-3692-7169
7Park KHKyu Hyunghttps://orcid.org/0000-0002-5516-8121

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Drug DiscoveryMajor topic
Neovascularization, PathologicMajor topic
Humans
Deep Learning
Vascular Endothelial Growth Factor A
Data Mining

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
Korean Retina FoundationPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References46

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
140,971,592A retrieval-augmented knowledge mining method with deep thinking LLMs for biomedical research and clinical support.Gigascience2025https://conductscience.org/library/papers/40971592PubMed
238,782,152Anti-angiogenic biomolecules in neovascular age-related macular degeneration; therapeutics and drug delivery systems.Int J Pharm2024https://conductscience.org/library/papers/38782152PubMed
331,522,845Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled trial.Lancet2019https://conductscience.org/library/papers/31522845PubMed
419,486,540Fpocket: an open source platform for ligand pocket detection.BMC Bioinformatics2009https://conductscience.org/library/papers/19486540PubMed
537,142,441Beyond VEGF: Targeting Inflammation and Other Pathways for Treatment of Retinal Disease.J Pharmacol Exp Ther2023https://conductscience.org/library/papers/37142441PubMed
623,233,163HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells.Int J Oncol2013https://conductscience.org/library/papers/23233163PubMed
739,237,523An artificial intelligence accelerated virtual screening platform for drug discovery.Nat Commun2024https://conductscience.org/library/papers/39237523PubMed
825,598,837Targeting Neovascularization in Ischemic Retinopathy: Recent Advances.Expert Rev Ophthalmol2013https://conductscience.org/library/papers/25598837PubMed
930,699,115Inherent versus induced protein flexibility: Comparisons within and between apo and holo structures.PLoS Comput Biol2019https://conductscience.org/library/papers/30699115PubMed
1026,113,211Molecular pathogenesis of retinal and choroidal vascular diseases.Prog Retin Eye Res2015https://conductscience.org/library/papers/26113211PubMed

1 to 10 of 46

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 0 citations.

None in this release.

Genes7

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FGF12,246PubTator's text mininghttps://conductscience.org/library/genes/2246NCBI Gene
FGF22,247PubTator's text mininghttps://conductscience.org/library/genes/2247NCBI Gene
HGF3,082PubTator's text mininghttps://conductscience.org/library/genes/3082NCBI Gene
IL1B3,553PubTator's text mininghttps://conductscience.org/library/genes/3553NCBI Gene
MMP94,318PubTator's text mininghttps://conductscience.org/library/genes/4318NCBI Gene
TGFB17,040PubTator's text mininghttps://conductscience.org/library/genes/7040NCBI Gene
VEGFA7,422PubTator's text mininghttps://conductscience.org/library/genes/7422NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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