Disease · HP_0001518
Small for gestational age
6 sourcesdiseases-2026-09-18-0.1.0
Cite this record
ConductScience Library. Small for gestational age. Diseases, record HP_0001518. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/HP_0001518
On this page
Disease
Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.
- Name
- Small for gestational age
- Open Targets ID
- HP_0001518
- Other names
- Birth weight less than 10th percentile, Low birth weight
- Highest stage of its drugs
- Phase 3, for 4 of its 15 drugs, from ClinicalTrials.gov
Source Open Targets
Drugs15
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Drug | ChEMBL ID | Type | Open Targets' stage | Stage reported by | Reports | Of them trials | Trials shown here | Source |
|---|---|---|---|---|---|---|---|---|
| SOMATROPIN | CHEMBL1201621 | Protein | Phase 3 | ClinicalTrials.gov | 10 | 10 | 9 | Drugs and targets |
| (+/-)NICOTINE | CHEMBL440464 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| LONAPEGSOMATROPIN | CHEMBL4298185 | Protein | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| NICOTINE | CHEMBL3 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| PROGESTERONE | CHEMBL103 | Small molecule | Phase 2 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| FERRIC CARBOXYMALTOSE | CHEMBL2108597 | Phase 1/2 | ClinicalTrials.gov | 2 | 2 | 1 | Drugs and targets | |
| IRON ISOMALTOSIDE 1000 | CHEMBL4298046 | Phase 1/2 | ClinicalTrials.gov | 2 | 2 | 0 | Drugs and targets | |
| FERRIC OXYHYDROXIDE | CHEMBL4802224 | Small molecule | Phase 1/2 | ClinicalTrials.gov | 1 | 1 | 0 | Drugs and targets |
| FERROUS SULFATE | CHEMBL1200830 | Small molecule | Phase 1/2 | ClinicalTrials.gov | 1 | 1 | 0 | Drugs and targets |
| FERRIC DERISOMALTOSE | CHEMBL4298187 | Oligosaccharide | Unknown | ClinicalTrials.gov | 1 | 1 | 0 | Drugs and targets |
1 to 10 of 15
See all 15 drugsTargets5
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| GHR | Growth hormone receptor | 2 | Growth hormone receptor agonist | Phase 3 | https://conductscience.org/library/genes/2690 | Drugs and targets |
| GNRHR | Gonadotropin-releasing hormone receptor | 2 | Gonadotropin-releasing hormone receptor agonist | Unknown | https://conductscience.org/library/genes/2798 | Drugs and targets |
| CHRNA4 | Neuronal acetylcholine receptor; alpha4/beta2 | 1 | Neuronal acetylcholine receptor; alpha4/beta2 agonist | Phase 3 | https://conductscience.org/library/genes/1137 | Drugs and targets |
| CHRNB2 | Neuronal acetylcholine receptor; alpha4/beta2 | 1 | Neuronal acetylcholine receptor; alpha4/beta2 agonist | Phase 3 | https://conductscience.org/library/genes/1141 | Drugs and targets |
| PGR | Progesterone receptor | 1 | Progesterone receptor agonist | Phase 2 | https://conductscience.org/library/genes/5241 | Drugs and targets |
Trials12
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 3 more are not shown, since the checks do not confirm them.
| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01067352 | A Trial to Evaluate the Correlation Between Spontaneous Catch-up Growth, Clinical Response to Saizen (Recombinant Human Growth Hormone, r-hGH) and Gene Expression Profiling in Children Small for Gestational Age (SGA) | Phase 3 | 25 | 2011-12-14 | Infant, Small for Gestational Age | SOMATROPIN | Its record names the disease | ClinicalTrials.gov |
| NCT00960128 | Observational Prospective Study on Patients Treated With Norditropin® | 21,249 | Growth Hormone Disorder, Growth Hormone Deficiency in Children, Adult Growth Hormone Deficiency, Genetic Disorder, Turner Syndrome, Foetal Growth Problem, Small for Gestational Age, Chronic Kidney Disease, Chronic Renal Insufficiency, Noonan Syndrome | SOMATROPIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT06110910 | Long-term Efficacy and Safety Evaluation of Growth Hormone in Children in China(CGLS) | 10,000 | Childhood Short Stature | SOMATROPIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT05504863 | RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study | 538 | Iron Deficiency Anemia, Neurodevelopmental Abnormality, Autism Spectrum Disorder | FERRIC CARBOXYMALTOSE, FERRIC SULFATE | Its record names the disease | ClinicalTrials.gov | ||
| NCT00507975 | Study of Nicotine Patch in Pregnancy (SNIPP) | Phase 3 | 404 | Smoking | (+/-)NICOTINE, NICOTINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01578135 | French National Registry of Children Born Small for Gestational Age Treated With Somatropin | 291 | Growth Disorder, Small for Gestational Age | SOMATROPIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT01897753 | Retrospective Study Of The Influence Of Age At Start Of Growth Hormone Treatment On Height Gain In Children Born Small for Gestational Age | 264 | Small For Gestational Age (SGA) | SOMATROPIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT07221851 | Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders | Phase 3 | 186 | Turner Syndrome, Short Stature Homeobox Gene Mutation, Idiopathic Short Stature, Small for Gestational Age at Delivery | LONAPEGSOMATROPIN, SOMATROPIN | Its record names the disease | ClinicalTrials.gov | |
| NCT00787878 | Long Term Metabolic Safety of Norditropin® Treatment of Small for Gestational Age (SGA) Subjects | 153 | Foetal Growth Problem, Small for Gestational Age | SOMATROPIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT03221933 | A Study of Recombinant Human Growth Hormone Injection（JINTOPIN AQ）for Short Children With Small for SGA | Phase 2 | 120 | Small for Gestational Age Infant | SOMATROPIN | Its record names the disease | ClinicalTrials.gov |
1 to 10 of 12
See all 12 trialsComparisons in its trials0
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
None in this release.
Papers from its trials21
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Data dates
The date of each source this release read.
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this disease from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/diseases/v1/HP_0001518
GET https://conductscience.org/api/diseases/v1/HP_0001518/papers?page=2