Paper · 14520460

FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells.

Sturla LM and 2 others. Br J Cancer, 2003. Cited by 20 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells. Papers, record 14520460. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/14520460

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells.; PubMed
Journal: Br J Cancer; PubMed
Year: 2003; PubMed
Publication types: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/14520460/; PubMed
DOI: https://doi.org/10.1038/sj.bjc.6601249; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2394287/; PubMed
The journal: https://conductscience.org/library/journal-index/0370635; PubMed
Citations, by iCite: 20; iCite
Relative citation ratio, by iCite: 0.33; iCite
Revised in PubMed: 2022-03-17; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Sturla LM	L-M
2	Merrick AE	A E
3	Burchill SA	S A

Source PubMed

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Alternative Splicing	Major topic
Gene Expression Regulation, Neoplastic	Major topic
Neoplasms	Major topic
Protein-Tyrosine Kinases	Major topic
Receptors, Fibroblast Growth Factor	Major topic
Blotting, Southern
Cell Division
DNA Primers
Exons
Fibroblast Growth Factor 1
Fibroblast Growth Factor 2
Humans
Immunoglobulins
Oligonucleotides, Antisense
Phosphorylation
Polymerase Chain Reaction
Protein Isoforms
RNA, Messenger
Receptor, Fibroblast Growth Factor, Type 3
Tissue Distribution
Tumor Cells, Cultured

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References39

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	11,395,371	Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors.	Am J Pathol	2001	https://conductscience.org/library/papers/11395371	PubMed
2	10,648,414	Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis.	Blood	2000	https://conductscience.org/library/papers/10648414	PubMed
3	11,529,856	Analysis of FGFR3 gene mutations in multiple myeloma patients with t(4;14).	Br J Haematol	2001	https://conductscience.org/library/papers/11529856	PubMed
4	10,098,411	RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer.	Trends Genet	1999	https://conductscience.org/library/papers/10098411	PubMed
5	10,433,902	Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development.	Development	1999	https://conductscience.org/library/papers/10433902	PubMed
6	10,471,491	Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.	Nat Genet	1999	https://conductscience.org/library/papers/10471491	PubMed
7	1,646,484	Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation.	Science	1991	https://conductscience.org/library/papers/1646484	PubMed
8	9,582,336	Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia.	J Biol Chem	1998	https://conductscience.org/library/papers/9582336	PubMed
9	10,594,778	Expression and localization of fibroblast growth factors and fibroblast growth factor receptors in the developing rat kidney.	Kidney Int	1999	https://conductscience.org/library/papers/10594778	PubMed
10	11,906,172	Identification and characterization of soluble isoform of fibroblast growth factor receptor 3 in human SaOS-2 osteosarcoma cells.	Biochem Biophys Res Commun	2002	https://conductscience.org/library/papers/11906172	PubMed

1 to 10 of 39

See all 39 references

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 20 citations.

PMID	Title	Journal	Year	In Papers	Source
42,693,342	Regulation of PDGF-BB signaling in placental pericytes by soluble PDGFRβ isoforms: implications for fetoplacental vascular development.	Angiogenesis	2026	https://conductscience.org/library/papers/42693342	PubMed
41,584,352	Unraveling the FGFR-RNA splicing axis: Mechanisms, oncogenic crosstalks and innovations for therapeutic purpose.	Acta Pharm Sin B	2026	https://conductscience.org/library/papers/41584352	PubMed
36,794,128	High expression of FGFR3 predicts a better prognosis for patients with non-small cell lung cancer in a Chinese population.	J Thorac Dis	2023	https://conductscience.org/library/papers/36794128	PubMed
36,107,237	Differential expression profiling of onco and tumor-suppressor genes from major-signaling pathways in Wilms' tumor.	Pediatr Surg Int	2022	https://conductscience.org/library/papers/36107237	PubMed
33,804,608	Members of the Fibroblast Growth Factor Receptor Superfamily Are Proteolytically Cleaved by Two Differently Activated Metalloproteases.	Int J Mol Sci	2021	https://conductscience.org/library/papers/33804608	PubMed
23,696,738	Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).	PLoS Pathog	2013	https://conductscience.org/library/papers/23696738	PubMed
22,531,302	Molecular markers associated with nonepithelial ovarian cancer in formalin-fixed, paraffin-embedded specimens by genome wide expression profiling.	Kaohsiung J Med Sci	2012	https://conductscience.org/library/papers/22531302	PubMed
22,203,889	Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer.	J Nucleic Acids	2012	https://conductscience.org/library/papers/22203889	PubMed
18,369,415	Entropy measures quantify global splicing disorders in cancer.	PLoS Comput Biol	2008	https://conductscience.org/library/papers/18369415	PubMed
17,912,529	Role of FGFR3 in urothelial cell carcinoma: biomarker and potential therapeutic target.	World J Urol	2007	https://conductscience.org/library/papers/17912529	PubMed

Genes13

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
B2M	567	PubTator's text mining	https://conductscience.org/library/genes/567	NCBI Gene
CYCS	54,205	PubTator's text mining	https://conductscience.org/library/genes/54205	NCBI Gene
EGF	1,950	PubTator's text mining	https://conductscience.org/library/genes/1950	NCBI Gene
EPHB2	2,048	PubTator's text mining	https://conductscience.org/library/genes/2048	NCBI Gene
FGF1	2,246	PubTator's text mining	https://conductscience.org/library/genes/2246	NCBI Gene
FGF2	2,247	PubTator's text mining	https://conductscience.org/library/genes/2247	NCBI Gene
FGF8	2,253	PubTator's text mining	https://conductscience.org/library/genes/2253	NCBI Gene
FGFR1	2,260	PubTator's text mining	https://conductscience.org/library/genes/2260	NCBI Gene
FGFR3	2,261	PubTator's text mining	https://conductscience.org/library/genes/2261	NCBI Gene
FGFR4	2,264	PubTator's text mining	https://conductscience.org/library/genes/2264	NCBI Gene

1 to 10 of 13

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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