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Paper · 32879300

FGF/FGFR signaling in health and disease.

Xie Y and 14 others. Signal Transduct Target Ther, 2020. Cited by 751 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. FGF/FGFR signaling in health and disease. Papers, record 32879300. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/32879300

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
FGF/FGFR signaling in health and disease.
PubMed
Journal
Signal Transduct Target Ther
PubMed
Year
2020
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
Citations, by iCite
751
iCite
Relative citation ratio, by iCite
36.6
iCite
Revised in PubMed
2024-08-01
PubMed

Authors15

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Xie YYangli
2Su NNan
3Yang JJing
4Tan QQiaoyan
5Huang SShuohttps://orcid.org/0000-0001-9495-4339
6Jin MMin
7Ni ZZhenhong
8Zhang BBin
9Zhang DDali
10Luo FFengtao

1 to 10 of 15Source PubMed

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Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Embryonic DevelopmentMajor topic
Fibroblast Growth FactorsMajor topic
HomeostasisMajor topic
Receptors, Fibroblast Growth FactorMajor topic
Apoptosis
Cell Differentiation
Cell Proliferation
Humans
Neoplasms
Signal Transduction

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References747

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
116,501,574Mutations in different components of FGF signaling in LADD syndrome.Nat Genet2006https://conductscience.org/library/papers/16501574PubMed
217,205,557Local application of recombinant human fibroblast growth factor-2 on bone repair: a dose-escalation prospective trial on patients with osteotomy.J Orthop Res2007https://conductscience.org/library/papers/17205557PubMed
320,084,103Kidney development in the absence of Gdnf and Spry1 requires Fgf10.PLoS Genet2010https://conductscience.org/library/papers/20084103PubMed
418,789,890Gain-of-function mutation of FGFR3 results in impaired fracture healing due to inhibition of chondrocyte differentiation.Biochem Biophys Res Commun2008https://conductscience.org/library/papers/18789890PubMed
57,773,297Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.Nat Genet1995https://conductscience.org/library/papers/7773297PubMed
626,906,157Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.Invest Ophthalmol Vis Sci2016https://conductscience.org/library/papers/26906157PubMed
721,894,256Altered expression of tissue remodeling genes in a mouse model of acute allergic rhinitis.Int Forum Allergy Rhinol2011https://conductscience.org/library/papers/21894256PubMed
830,082,912FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.Oncogene2019https://conductscience.org/library/papers/30082912PubMed
917,071,719FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation.Am J Physiol Lung Cell Mol Physiol2007https://conductscience.org/library/papers/17071719PubMed
1019,821,490Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma.Int J Cancer2010https://conductscience.org/library/papers/19821490PubMed

1 to 10 of 747

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Cited by545

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 751 citations.

PMIDTitleJournalYearIn PapersSource
42,967,007Change-of-function fibroblast growth factor receptor 3 mutations causing skeletal dysplasias.J Cell Commun Signal2026https://conductscience.org/library/papers/42967007PubMed
42,962,029Photosynthetic chimeric stem cells function as mitochondrial batteries.Sci Adv2026https://conductscience.org/library/papers/42962029PubMed
42,953,735Spatiotemporally coordinated immunometabolic-hyperthermia therapy for diabetic bone defect regeneration.Mater Today Bio2026https://conductscience.org/library/papers/42953735PubMed
42,936,110Neuroprotective roles of Klotho signaling in Huntington's disease: From molecular insights to clinical translation.IBRO Neurosci Rep2026https://conductscience.org/library/papers/42936110PubMed
42,927,286EMSCs-derived exosomes rescue p75NTR-/- -mediated osteogenesis deficiency via PI3K/Akt/ERK1/2 signaling pathways.Mater Today Bio2026https://conductscience.org/library/papers/42927286PubMed
42,901,917Identification and validation of NCOA5-ZCCHC3/FGF22 axis as a prognostic marker in lung adenocarcinoma migration and invasion.Cell Death Dis2026https://conductscience.org/library/papers/42901917PubMed
42,890,469Recurring and isolated intronic FGFR1 variants as an underdiagnosed cause of congenital hypogonadotropic hypogonadism.J Endocr Soc2026https://conductscience.org/library/papers/42890469PubMed
42,883,713Fibroblast Growth Factors and Their Receptors in Major Depressive Disorder: A Scoping Review of Translational Research.Int J Mol Sci2026https://conductscience.org/library/papers/42883713PubMed
42,880,979Neuro-associated SEMA3C+ tumour cells promote gastric cancer peritoneal metastasis via EBF2-FGF7-FGFR2-mediated tumour-endothelial crosstalk.Clin Transl Med2026https://conductscience.org/library/papers/42880979PubMed
42,861,413FGFR kinase isoform and activation state modulate ATPase activity.iScience2026https://conductscience.org/library/papers/42861413PubMed

1 to 10 of 545

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Genes81

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ACKR357,007PubTator's text mininghttps://conductscience.org/library/genes/57007NCBI Gene
AFF33,899PubTator's text mininghttps://conductscience.org/library/genes/3899NCBI Gene
AHCYL110,768PubTator's text mininghttps://conductscience.org/library/genes/10768NCBI Gene
BAIAP2L155,971PubTator's text mininghttps://conductscience.org/library/genes/55971NCBI Gene
BMP4652PubTator's text mininghttps://conductscience.org/library/genes/652NCBI Gene
CCN21,490PubTator's text mininghttps://conductscience.org/library/genes/1490NCBI Gene
CD4920PubTator's text mininghttps://conductscience.org/library/genes/920NCBI Gene
CDH111,009PubTator's text mininghttps://conductscience.org/library/genes/1009NCBI Gene
CREB11,385PubTator's text mininghttps://conductscience.org/library/genes/1385NCBI Gene
E2F11,869PubTator's text mininghttps://conductscience.org/library/genes/1869NCBI Gene

1 to 10 of 81

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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