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Paper · 36964133

Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review.

Ruze R and 6 others. Signal Transduct Target Ther, 2023. Cited by 86 papers, by iCite.

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ConductScience Library. Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review. Papers, record 36964133. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36964133

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review.
PubMed
Journal
Signal Transduct Target Ther
PubMed
Year
2023
PubMed
Publication types
Journal Article, Systematic Review, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
86
iCite
Relative citation ratio, by iCite
8.44
iCite
Revised in PubMed
2024-01-02
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Ruze RRexiatihttps://orcid.org/0000-0002-0891-5307
2Song JJianlu
3Yin XXinpeng
4Chen YYuan
5Xu RRuiyuan
6Wang CChengcheng
7Zhao YYupei

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Diabetes MellitusMajor topic
Pancreatic NeoplasmsMajor topic
Humans
Carcinogenesis
Obesity
Pancreas
Tumor Microenvironment

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References541

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
131,638,645Advanced Glycation End Products: Building on the Concept of the "Common Soil" in Metabolic Disease.Endocrinology2020https://conductscience.org/library/papers/31638645PubMed
229,693,005Suppression of IL-6 Gene by shRNA Augments Gemcitabine Chemosensitization in Pancreatic Adenocarcinoma Cells.Biomed Res Int2018https://conductscience.org/library/papers/29693005PubMed
323,934,186The Yin and Yang of Toll-like receptors in cancer.Oncogene2014https://conductscience.org/library/papers/23934186PubMed
423,671,428Biochemistry of adipose tissue: an endocrine organ.Arch Med Sci2013https://conductscience.org/library/papers/23671428PubMed
530,856,230Nicotinamide phosphoribosyltransferase expression and clinical outcome of resected stage I/II pancreatic ductal adenocarcinoma.PLoS One2019https://conductscience.org/library/papers/30856230PubMed
624,378,801Therapeutic opportunities of the IL-22-IL-22R1 system.Nat Rev Drug Discov2014https://conductscience.org/library/papers/24378801PubMed
721,779,469Involvement of interleukin-6 and androgen receptor signaling in pancreatic cancer.Genes Cancer2010https://conductscience.org/library/papers/21779469PubMed
834,066,392Crown-Like Structures in Breast Adipose Tissue: Early Evidence and Current Issues in Breast Cancer.Cancers (Basel)2021https://conductscience.org/library/papers/34066392PubMed
925,356,037SIBLINGs and SPARC families: their emerging roles in pancreatic cancer.World J Gastroenterol2014https://conductscience.org/library/papers/25356037PubMed
1026,715,642Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia.Cancer Discov2016https://conductscience.org/library/papers/26715642PubMed

1 to 10 of 541

See all 541 references

Cited by64

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 86 citations.

PMIDTitleJournalYearIn PapersSource
42,958,510Association between a combined lifestyle exposure index and age at pancreatic cancer diagnosis: a hospital-based retrospective study.BMC Gastroenterol2026https://conductscience.org/library/papers/42958510PubMed
42,724,341Metabolic reprogramming in diabetes and cancer: the role of PI3K/AKT/mTOR and beyond.Am J Cancer Res2026https://conductscience.org/library/papers/42724341PubMed
42,699,280Microbiome-based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review).Oncol Lett2026https://conductscience.org/library/papers/42699280PubMed
42,683,279Performance of risk prediction models for pancreatic cancer in patients with new-onset diabetes: a systematic review and meta-analysis.Front Oncol2026https://conductscience.org/library/papers/42683279PubMed
42,680,727Immune checkpoints and immunoregulation in metabolic diseases and cancers: pathological mechanisms and therapeutic potential.Signal Transduct Target Ther2026https://conductscience.org/library/papers/42680727PubMed
42,668,993Survival rate in patients with pancreatic cancer in Guilan province, Iran.Caspian J Intern Med2026https://conductscience.org/library/papers/42668993PubMed
42,640,901Burden of early-onset pancreatic cancer and its association with risk factors in women of childbearing age.PLoS One2026https://conductscience.org/library/papers/42640901PubMed
42,625,611Distinct prognostic impact of diabetes subtypes, metformin use, and glycemic control in pancreatic cancer: a systematic review and meta-analysis of cohort studies.Front Oncol2026https://conductscience.org/library/papers/42625611PubMed
42,549,759Cardiovascular-Kidney-Metabolic Syndrome Severity and Risk of Pancreatic Cancer in a Large Prospective Cohort.Diabetes Metab Res Rev2026https://conductscience.org/library/papers/42549759PubMed
42,511,782Integrating Network Toxicology with Molecular Dynamics Simulations to Reveal Key Targets and Binding Mechanisms of Bisphenol A in Pancreatic Ductal Adenocarcinoma.Int J Mol Sci2026https://conductscience.org/library/papers/42511782PubMed

1 to 10 of 64

See all 64 cited by

Genes249

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ACACA31PubTator's text mininghttps://conductscience.org/library/genes/31NCBI Gene
ACAT138PubTator's text mininghttps://conductscience.org/library/genes/38NCBI Gene
ACKR12,532PubTator's text mininghttps://conductscience.org/library/genes/2532NCBI Gene
ACLY47PubTator's text mininghttps://conductscience.org/library/genes/47NCBI Gene
ACTA158PubTator's text mininghttps://conductscience.org/library/genes/58NCBI Gene
ADAM10102PubTator's text mininghttps://conductscience.org/library/genes/102NCBI Gene
ADIPOQ9,370PubTator's text mininghttps://conductscience.org/library/genes/9370NCBI Gene
AGER177PubTator's text mininghttps://conductscience.org/library/genes/177NCBI Gene
AGR210,551PubTator's text mininghttps://conductscience.org/library/genes/10551NCBI Gene
AHR196PubTator's text mininghttps://conductscience.org/library/genes/196NCBI Gene

1 to 10 of 249

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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