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Disease · MONDO_0002113

peritoneal carcinoma

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. peritoneal carcinoma. Diseases, record MONDO_0002113. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0002113

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
peritoneal carcinoma
Open Targets
Open Targets ID
MONDO_0002113
Open Targets
Other names
carcinoma of peritoneum, peritoneum carcinoma
Open Targets
Disease Ontology
DOID:1791
Disease Ontology
Highest stage of its drugs
Phase 3, for 7 of its 18 drugs, from ClinicalTrials.gov
Open Targets

Drugs18

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
CARBOPLATINCHEMBL1351Small moleculePhase 3ClinicalTrials.gov101010Drugs and targets
PACLITAXELCHEMBL428647Small moleculePhase 3ClinicalTrials.gov999Drugs and targets
BEVACIZUMABCHEMBL1201583AntibodyPhase 3ClinicalTrials.gov666Drugs and targets
OREGOVOMABCHEMBL2107917AntibodyPhase 3ClinicalTrials.gov442Drugs and targets
CISPLATINCHEMBL11359Small moleculePhase 3ClinicalTrials.gov333Drugs and targets
DOXORUBICINCHEMBL53463Small moleculePhase 3ClinicalTrials.gov222Drugs and targets
GEMCITABINECHEMBL888Small moleculePhase 3ClinicalTrials.gov222Drugs and targets
DOXORUBICIN HYDROCHLORIDECHEMBL359744Small moleculePhase 2ClinicalTrials.gov222Drugs and targets
TOPOTECANCHEMBL84Small moleculePhase 2ClinicalTrials.gov222Drugs and targets
BICALUTAMIDECHEMBL409Small moleculePhase 2ClinicalTrials.gov111Drugs and targets

1 to 10 of 18

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Targets51

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
CSF1RMacrophage colony-stimulating factor 1 receptor2Macrophage colony stimulating factor receptor inhibitorPhase 2https://conductscience.org/library/genes/1436Drugs and targets
FLT1Vascular endothelial growth factor receptor2Vascular endothelial growth factor receptor 1 inhibitor; Vascular endothelial growth factor receptor inhibitorPhase 2https://conductscience.org/library/genes/2321Drugs and targets
FLT4Vascular endothelial growth factor receptor2Vascular endothelial growth factor receptor 3 inhibitor; Vascular endothelial growth factor receptor inhibitorPhase 2https://conductscience.org/library/genes/2324Drugs and targets
KDRVascular endothelial growth factor receptor2Vascular endothelial growth factor receptor 2 inhibitor; Vascular endothelial growth factor receptor inhibitorPhase 2https://conductscience.org/library/genes/3791Drugs and targets
KITMast/stem cell growth factor receptor Kit2Stem cell growth factor receptor inhibitorPhase 2https://conductscience.org/library/genes/3815Drugs and targets
PDGFRAPlatelet-derived growth factor receptor2Platelet-derived growth factor receptor alpha inhibitor; Platelet-derived growth factor receptor inhibitorPhase 2https://conductscience.org/library/genes/5156Drugs and targets
PDGFRBPlatelet-derived growth factor receptor2Platelet-derived growth factor receptor beta inhibitor; Platelet-derived growth factor receptor inhibitorPhase 2https://conductscience.org/library/genes/5159Drugs and targets
TOP2ADNA topoisomerase 2-alpha2DNA topoisomerase II alpha inhibitorPhase 3https://conductscience.org/library/genes/7153Drugs and targets
ARAndrogen receptor1Androgen Receptor antagonistPhase 2https://conductscience.org/library/genes/367Drugs and targets
FGFR1Fibroblast growth factor receptor 11Fibroblast growth factor receptor 1 inhibitorPhase 1/2https://conductscience.org/library/genes/2260Drugs and targets

1 to 10 of 51

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Trials20

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00316173Second-Line Therapy Study For Potentially Platinum-Sensitive Relapsed Ovarian CancerPhase 2772009-11-26Ovarian Cancer, Neoplasms, OvarianCARBOPLATIN, TOPOTECANIts record names the diseaseClinicalTrials.gov
NCT00407563Bevacizumab With Abraxane in Patients With Recurrent Ovarian/ Peritoneal CancerPhase 2482012-04-05Epithelial Ovarian Cancer, Primary Peritoneal CarcinomaBEVACIZUMAB, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT00768144Sunitinib in Recurrent and Refractory Ovarian, Fallopian Tube and Peritoneal CarcinomaPhase 2362014-12-02Ovarian Cancer, Fallopian Tube Cancer, Peritoneal CancerSUNITINIBIts record names the diseaseClinicalTrials.gov
NCT02834975Pembrolizumab, Paclitaxel, and Carboplatin in Patients With Advanced Stage Epithelial Ovarian Cancer (EOC).Phase 2262023-11-07Fallopian Tube Cancer, Peritoneum Cancer, Epithelial Ovarian CancerCARBOPLATIN, PACLITAXEL, PEMBROLIZUMABIts record names the diseaseClinicalTrials.gov
NCT00511992Study of Bevacizumab Followed by Bevacizumab Consolidation for Ovarian CancerPhase 2202017-07-02Advanced Ovarian Carcinoma, Primary Peritoneal Carcinoma, Ovarian CarcinosarcomaBEVACIZUMAB, CISPLATIN, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT01936974(PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and Peritoneal CarcinomaPhase 272017-10-25Ovarian Carcinoma, Fallopian Tube Carcinoma, Peritoneal CarcinomaBEVACIZUMAB, CARBOPLATIN, CISPLATIN, GEMCITABINE, OXALIPLATINIts record names the diseaseClinicalTrials.gov
NCT00003636Chemotherapy Plus Surgery in Treating Patients With Stage III or Stage IV Ovarian, Peritoneal, or Fallopian Tube CancerPhase 3704Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity CancerCARBOPLATIN, CISPLATINIts record names the diseaseClinicalTrials.gov
NCT01837251Evaluation of Optimal Treatment With Bevacizumab in Patients With Platinum-sensitive Recurrent Ovarian CancerPhase 3682Recurrent Platinum-sensitive Ovarian CancerBEVACIZUMAB, CARBOPLATIN, DOXORUBICIN, GEMCITABINEIts record names the diseaseClinicalTrials.gov
NCT04498117Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking SurgeryPhase 3615
Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma, Fallopian Tube Neoplasms, Fallopian Tube Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Peritoneal Cancer, Peritoneal Carcinoma, Peritoneal Neoplasms
CARBOPLATIN, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT05080946Using Aspirin to Improve Immunological Features of Ovarian TumorsEarly phase 1100Ovarian Cancer, Fallopian Tube Cancer, Peritoneal CancerASPIRINIts record names the diseaseClinicalTrials.gov

1 to 10 of 20

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Comparisons in its trials1

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrial
Dose-finding Phase vs Activity Assessment Phase: serious adverse events6 of 2212 of 5577NCT00316173

Papers from its trials12

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
32305099RESULT1PubMed
31916979RESULT1PubMed
31897661RESULT1PubMed
20850296RESULT1PubMed
20818904RESULT1PubMed
17918264RESULT1PubMed
16959305RESULT1PubMed
37000264DERIVED1PubMed
29324537DERIVED1PubMed
25964591DERIVED1PubMed

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0002113

GET https://conductscience.org/api/diseases/v1/MONDO_0002113/targets?page=2