Drug · CHEMBL703
SUXAMETHONIUM
7 sourcespipelines-2026-09-18-0.3.1
Cite this record
ConductScience Library. SUXAMETHONIUM. Drugs and targets, record CHEMBL703. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL703
On this page
Drug
Names and IDs as ChEMBL gives them, through Open Targets.
- Other names
- Succinylcholine, Succinylcholine cation, Succinylcholine ion, Suxamethonium cation, Suxamethonium ion
- ChEMBL
Targets5
The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.
| Target | Protein | Mechanism | Action | Gene in Genes |
|---|---|---|---|---|
| CHRNA1 | Muscle-type nicotinic acetylcholine receptor | Muscle-type nicotinic acetylcholine receptor agonist | AGONIST | https://conductscience.org/library/genes/1134 |
| CHRNB1 | Muscle-type nicotinic acetylcholine receptor | Muscle-type nicotinic acetylcholine receptor agonist | AGONIST | https://conductscience.org/library/genes/1140 |
| CHRND | Muscle-type nicotinic acetylcholine receptor | Muscle-type nicotinic acetylcholine receptor agonist | AGONIST | https://conductscience.org/library/genes/1144 |
| CHRNE | Muscle-type nicotinic acetylcholine receptor | Muscle-type nicotinic acetylcholine receptor agonist | AGONIST | https://conductscience.org/library/genes/1145 |
| CHRNG | Muscle-type nicotinic acetylcholine receptor | Muscle-type nicotinic acetylcholine receptor agonist | AGONIST | https://conductscience.org/library/genes/1146 |
Source ChEMBL
Diseases7
The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Disease | Open Targets' stage | Stage reported by | Reports | Of them trials | Its drugs |
|---|---|---|---|---|---|
| depressive disorder | Unknown | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0002050 |
| ischemic stroke | Phase 3 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_1060198 |
| major depressive disorder | Unknown | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0002009 |
| osteoarthritis | Unknown | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0005178 |
| pneumothorax | Unknown | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0002076 |
| psychiatric disorder | Unknown | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0002025 |
| muscle cramp | Approval | TTD | 1 | 0 | https://conductscience.org/library/drugs?q=EFO_0009846 |
Source Open Targets
Trials28
Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more that Open Targets linked to it is not shown, since the release's checks do not confirm it.
| Trial | Title | Phase | Participants | Results first posted | Named as | Linked by | Source |
|---|---|---|---|---|---|---|---|
| NCT00355368 | Succinylcholine Versus Rocuronium for Emergency Intubation in Intensive Care | Phase 4 | 420 | 2011-12-15 | succinylcholine | Its name | ClinicalTrials.gov |
| NCT04581395 | The Effect of Pretreatment With Roc on Succinylcholine Myalgias | Phase 3 | 300 | 2024-05-16 | succinylcholine | Its name | ClinicalTrials.gov |
| NCT01907217 | Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression | Phase 4 | 138 | 2018-11-14 | suxamethonium | Its name | ClinicalTrials.gov |
| NCT02635542 | Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery | Phase 4 | 100 | 2018-07-17 | succinylcholine | Its name | ClinicalTrials.gov |
| NCT01941628 | Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine | Phase 4 | 91 | 2019-02-11 | succinylcholine | Its name | ClinicalTrials.gov |
| NCT02329964 | Effectiveness of Sugammadex in LMS Surgery | Phase 4 | 80 | 2015-09-28 | succinylcholine | Its name | ClinicalTrials.gov |
| NCT00986583 | Effect of Succinylcholine on Patients Using Statins | 70 | 2016-08-02 | succinylcholine | Its name | ClinicalTrials.gov | |
| NCT01441960 | Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT) | 45 | 2015-06-02 | succinylcholine | Its name | ClinicalTrials.gov | |
| NCT02425449 | Fade Upon TOF Stimulation Induced by Succinylcholine | Phase 4 | 19 | 2018-01-02 | succinylcholine | Its name | ClinicalTrials.gov |
| NCT02914119 | Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals | 30,430 | 2019-09-12 | suxamethonium | Its name | ClinicalTrials.gov |
1 to 10 of 28
See all 28 trialsComparisons in its trials15
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Succinylcholine vs Rocuronium: serious adverse events | 0 of 210 | 0 of 210 | 420 | NCT00355368 | Trial comparisons |
| Succinylcholine vs Rocuronium: Number of Participants With an Failed First Intubation Attempts | 32 of 200 | 36 of 200 | 400 | NCT00355368 | Trial comparisons |
| Succinylcholine vs Rocuronium: Number of Participants Exhibiting Desaturation >5% | 73 of 200 | 66 of 200 | 400 | NCT00355368 | Trial comparisons |
| Bilateral ECT Mecta 5000M vs High-dose Unilateral ECT Mecta 5000M: serious adverse events | 9 of 69 | 7 of 69 | 138 | NCT01907217 | Trial comparisons |
| Group CIS vs Group SUX: Number of Participants With Postoperative Pulmonary Complications | 8 of 50 | 8 of 50 | 100 | NCT02635542 | Trial comparisons |
| Group CIS vs Group SUX: deaths from any cause | 0 of 50 | 0 of 50 | 100 | NCT02635542 | Trial comparisons |
| Group CIS vs Group SUX: serious adverse events | 0 of 50 | 0 of 50 | 100 | NCT02635542 | Trial comparisons |
| NMBA: Succinylcholine vs NMBA: Rocuronium: serious adverse events | 0 of 45 | 0 of 45 | 90 | NCT01441960 | Trial comparisons |
| Rocuronium vs Succinylcholine: Peroperative and Postoperative Surgical Complication | 0 of 45 | 0 of 45 | 90 | NCT01941628 | Trial comparisons |
| Rocuronium vs Succinylcholine: Number of Participants With Newborn in Need of Respiratory Support | 0 of 45 | 0 of 45 | 90 | NCT01941628 | Trial comparisons |
1 to 10 of 15
See all 15 comparisons in its trialsPapers from its trials13
The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
| PMID | Listed as | Trials listing it | Source |
|---|---|---|---|
| 35226737 | RESULT | 1 | PubMed |
| 19387176 | RESULT | 1 | PubMed |
| 41566470 | DERIVED | 1 | PubMed |
| 36858270 | DERIVED | 1 | PubMed |
| 35950901 | DERIVED | 1 | PubMed |
| 35857365 | DERIVED | 1 | PubMed |
| 34752484 | DERIVED | 1 | PubMed |
| 34383393 | DERIVED | 1 | PubMed |
| 31846014 | DERIVED | 1 | PubMed |
| 31154292 | DERIVED | 1 | PubMed |
1 to 10 of 13
See all 13 papers from its trialsTests in its trials0
The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.
None in this release.
Data dates
The date of each source this release read.
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this drug from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL703
GET https://conductscience.org/api/drugs/v1/CHEMBL703/trials?page=2