Paper · 16465403
FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells.
Katoh Y and 1 other. Int J Mol Med, 2006. Cited by 55 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells. Papers, record 16465403. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16465403
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells.
- PubMed
Topics23
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Conserved Sequence | Major topic |
| Fibroblast Growth Factors | Major topic |
| Signal Transduction | Major topic |
| Stem Cells | Major topic |
| Wnt Proteins | Major topic |
| Amino Acid Sequence | |
| Animals | |
| Base Sequence | |
| Binding Sites | |
| Computational Biology | |
| Genome | |
| Genomics | |
| Humans | |
| Lymphoid Enhancer-Binding Factor 1 | |
| Mice | |
| Molecular Sequence Data | |
| Multigene Family | |
| Pan troglodytes | |
| Phylogeny | |
| Promoter Regions, Genetic | |
| RNA, Messenger | |
| Rats | |
| TCF Transcription Factors |
Source PubMed
Grants0
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None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
None in this release.
Cited by27
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 55 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,249,671 | Exosomal miR-4644 Targets SPRY3 to Promote Proliferation and Invasion of Pancreatic Cancer. | Cancer Med | 2026 | https://conductscience.org/library/papers/42249671 | PubMed |
| 40,257,378 | FGFR2 residence in primary cilia is necessary for epithelial cell signaling. | J Cell Biol | 2025 | https://conductscience.org/library/papers/40257378 | PubMed |
| 40,051,360 | Fibroblast Growth Factors: Roles and Emerging Therapeutic Applications. | Curr Drug Targets | 2025 | https://conductscience.org/library/papers/40051360 | PubMed |
| 39,227,612 | SPRED3 regulates the NF-κB signaling pathway in thyroid cancer and promotes the proliferation. | Sci Rep | 2024 | https://conductscience.org/library/papers/39227612 | PubMed |
| 38,895,124 | Role of long non-coding RNA in inflammatory bowel disease. | Front Immunol | 2024 | https://conductscience.org/library/papers/38895124 | PubMed |
| 37,643,784 | Pan-cancer Analysis Reveals Cancer-dependent Expression of SOX17 and Associated Clinical Outcomes. | Cancer Genomics Proteomics | 2023 | https://conductscience.org/library/papers/37643784 | PubMed |
| 36,384,366 | Sprouty4 is epigenetically upregulated in human colorectal cancer. | Epigenetics | 2023 | https://conductscience.org/library/papers/36384366 | PubMed |
| 34,184,730 | Quantitative analysis of signaling responses during mouse primordial germ cell specification. | Biol Open | 2021 | https://conductscience.org/library/papers/34184730 | PubMed |
| 33,445,626 | Non-Canonical Functions of the ARF Tumor Suppressor in Development and Tumorigenesis. | Biomolecules | 2021 | https://conductscience.org/library/papers/33445626 | PubMed |
| 30,082,912 | FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p. | Oncogene | 2019 | https://conductscience.org/library/papers/30082912 | PubMed |
1 to 10 of 27
See all 27 cited byGenes17
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AFG2A | 166,378 | PubTator's text mining | https://conductscience.org/library/genes/166378 | NCBI Gene |
| BCL9 | 607 | PubTator's text mining | https://conductscience.org/library/genes/607 | NCBI Gene |
| BCL9L | 283,149 | PubTator's text mining | https://conductscience.org/library/genes/283149 | NCBI Gene |
| CTNNB1 | 1,499 | PubTator's text mining | https://conductscience.org/library/genes/1499 | NCBI Gene |
| EGFR | 1,956 | PubTator's text mining | https://conductscience.org/library/genes/1956 | NCBI Gene |
| FGF1 | 2,246 | PubTator's text mining | https://conductscience.org/library/genes/2246 | NCBI Gene |
| FGF2 | 2,247 | PubTator's text mining | https://conductscience.org/library/genes/2247 | NCBI Gene |
| HNF4A | 3,172 | PubTator's text mining | https://conductscience.org/library/genes/3172 | NCBI Gene |
| LEF1 | 51,176 | PubTator's text mining | https://conductscience.org/library/genes/51176 | NCBI Gene |
| NUDT6 | 11,162 | PubTator's text mining | https://conductscience.org/library/genes/11162 | NCBI Gene |
1 to 10 of 17
See all 17 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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