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Paper · 20200314

Platelet tissue factor synthesis in type 2 diabetic patients is resistant to inhibition by insulin.

Gerrits AJ and 3 others. Diabetes, 2010. Cited by 88 papers, by iCite.

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ConductScience Library. Platelet tissue factor synthesis in type 2 diabetic patients is resistant to inhibition by insulin. Papers, record 20200314. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20200314

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Platelet tissue factor synthesis in type 2 diabetic patients is resistant to inhibition by insulin.
PubMed
Journal
Diabetes
PubMed
Year
2010
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
88
iCite
Relative citation ratio, by iCite
2.35
iCite
Revised in PubMed
2026-01-28
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gerrits AJAnja J
2Koekman CACornelis A
3van Haeften TWTimon W
4Akkerman JWJan Willem N

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Blood PlateletsMajor topic
Diabetes Mellitus, Type 2Major topic
InsulinMajor topic
ThromboplastinMajor topic
Alkaline Phosphatase
Blood Coagulation
Blood Pressure
Factor X
Glycated Hemoglobin
Humans
Middle Aged
Platelet Activation
Platelet Aggregation
RNA Precursors
RNA Splicing
Recombinant Proteins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References40

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
117,060,476Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets.J Exp Med2006https://conductscience.org/library/papers/17060476PubMed
216,843,179Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment.J Am Coll Cardiol2006https://conductscience.org/library/papers/16843179PubMed
317,365,860Thrombin-induced interleukin 1beta synthesis in platelet suspensions: impact of contaminating leukocytes.Platelets2007https://conductscience.org/library/papers/17365860PubMed
417,347,408Human platelets synthesize and express functional tissue factor.Blood2007https://conductscience.org/library/papers/17347408PubMed
517,594,903Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing.Exp Cell Res2007https://conductscience.org/library/papers/17594903PubMed
618,521,510Role of membrane cholesterol in platelet calcium signalling in response to VWF and collagen under stasis and flow.Thromb Haemost2008https://conductscience.org/library/papers/18521510PubMed
718,714,022Lipopolysaccharide is a direct agonist for platelet RNA splicing.J Immunol2008https://conductscience.org/library/papers/18714022PubMed
818,983,503Insulin inhibits tissue factor expression in monocytes.J Thromb Haemost2009https://conductscience.org/library/papers/18983503PubMed
910,827,198Micromolar Ca2+ concentrations are essential for Mg2+-dependent binding of collagen by the integrin alpha 2beta 1 in human platelets.J Biol Chem2000https://conductscience.org/library/papers/10827198PubMed
1011,259,926Diabetes mellitus: a hypercoagulable state.J Diabetes Complications2001https://conductscience.org/library/papers/11259926PubMed

1 to 10 of 40

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Cited by62

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 88 citations.

PMIDTitleJournalYearIn PapersSource
42,902,173Associations of estimated glucose disposal rate with chest pain prevalence and mortality risks: a population-based study.BMC Cardiovasc Disord2026https://conductscience.org/library/papers/42902173PubMed
42,073,459A Narrative Review on Abnormalities in the Hemostatic System in Diabetes Mellitus: Pathophysiology, Clinical Implications, and Therapeutics.Life (Basel)2026https://conductscience.org/library/papers/42073459PubMed
41,820,939Triglyceride-glucose index as a potential evaluation tool for all-cause mortality in ischemic stroke patients undergoing endovascular therapy: a multicenter cohort study.BMC Endocr Disord2026https://conductscience.org/library/papers/41820939PubMed
41,767,380Impact of TyG index on coronary plaques in patients with coronary artery disease under aggressive lipid-lowering therapy.Front Endocrinol (Lausanne)2026https://conductscience.org/library/papers/41767380PubMed
41,727,962
Associations of the triglyceride-glucose index, triglyceride glucose-body mass index, waist-triglyceride index and modified triglyceride-glucose indices with mortality in cardiovascular-kidney-metabolic syndrome stages 0-4: Evidence from NHANES 1999-2020.
J Transl Int Med2026https://conductscience.org/library/papers/41727962PubMed
41,165,399Association of Triglyceride-Glucose Index With Different Cardiovascular Diseases in Non-Diabetic Hypertension.J Cell Mol Med2025https://conductscience.org/library/papers/41165399PubMed
41,094,503
Longitudinal trajectories of the triglyceride-glucose index predict long-term major cardiovascular events in type 2 diabetes after simultaneous pancreas-kidney transplantation: a retrospective cohort study.
Lipids Health Dis2025https://conductscience.org/library/papers/41094503PubMed
41,019,316Triglyceride-glucose index as a novel prognostic biomarker for coronary artery disease: evidence from a large-scale prospective cohort study.Front Endocrinol (Lausanne)2025https://conductscience.org/library/papers/41019316PubMed
40,969,566Surrogate insulin resistance indices are associated with left atrial thrombus in patients with nonvalvular atrial fibrillation.Front Aging2025https://conductscience.org/library/papers/40969566PubMed
40,859,224The triglyceride-glucose index: updating evidence from clinical settings to molecular mechanisms in ageing-related cerebrovascular diseases.Cardiovasc Diabetol2025https://conductscience.org/library/papers/40859224PubMed

1 to 10 of 62

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Genes27

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AKT1207PubTator's text mininghttps://conductscience.org/library/genes/207NCBI Gene
APP351PubTator's text mininghttps://conductscience.org/library/genes/351NCBI Gene
CD14929PubTator's text mininghttps://conductscience.org/library/genes/929NCBI Gene
CLK11,195PubTator's text mininghttps://conductscience.org/library/genes/1195NCBI Gene
F102,159PubTator's text mininghttps://conductscience.org/library/genes/2159NCBI Gene
F22,147PubTator's text mininghttps://conductscience.org/library/genes/2147NCBI Gene
F32,152PubTator's text mininghttps://conductscience.org/library/genes/2152NCBI Gene
F82,157PubTator's text mininghttps://conductscience.org/library/genes/2157NCBI Gene
FGB2,244PubTator's text mininghttps://conductscience.org/library/genes/2244NCBI Gene
GAD12,571PubTator's text mininghttps://conductscience.org/library/genes/2571NCBI Gene

1 to 10 of 27

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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