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Paper · 32040934

The Osteocyte: New Insights.

Robling AG and 1 other. Annu Rev Physiol, 2020. Cited by 431 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The Osteocyte: New Insights. Papers, record 32040934. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/32040934

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The Osteocyte: New Insights.
PubMed
Journal
Annu Rev Physiol
PubMed
Year
2020
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Review
PubMed
Citations, by iCite
431
iCite
Relative citation ratio, by iCite
23.8
iCite
Revised in PubMed
2026-01-27
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Robling AGAlexander G
2Bonewald LFLynda F

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Bone and BonesMajor topic
OsteocytesMajor topic
Animals
Bone Remodeling
Fibroblast Growth Factor-23
Humans

Source PubMed

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P01 AR046798NIAMS NIH HHSUnited StatesP01AR046798PubMedNIH RePORTER
R61 AR073551NIAMS NIH HHSUnited StatesR61AR073551PubMed and NIHNIH RePORTER
R01 AR053237NIAMS NIH HHSUnited StatesR01AR053237PubMed and NIHNIH RePORTER
IK6 BX003783BLRD VAUnited StatesIK6BX003783PubMed and NIHNIH RePORTER
I01 BX001478BLRD VAUnited StatesI01BX001478PubMedNIH RePORTER
P01 AG039355NIA NIH HHSUnited StatesP01AG039355PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References145

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
116,081,646Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis.Endocrinology2005https://conductscience.org/library/papers/16081646PubMed
219,049,324Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue.J Bone Miner Res2009https://conductscience.org/library/papers/19049324PubMed
317,115,241Mechanism by which MLO-A5 late osteoblasts/early osteocytes mineralize in culture: similarities with mineralization of lamellar bone.Calcif Tissue Int2006https://conductscience.org/library/papers/17115241PubMed
417,512,530Extracellular NO signalling from a mechanically stimulated osteocyte.J Biomech2007https://conductscience.org/library/papers/17512530PubMed
510,646,115Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo.J Bone Miner Res2000https://conductscience.org/library/papers/10646115PubMed
621,419,885
Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it.
Bone2011https://conductscience.org/library/papers/21419885PubMed
725,708,054Quantifying the osteocyte network in the human skeleton.Bone2015https://conductscience.org/library/papers/25708054PubMed
827,341,653Identification of Senescent Cells in the Bone Microenvironment.J Bone Miner Res2016https://conductscience.org/library/papers/27341653PubMed
91,224,770Studies of the fossil dinosaur bone in the scanning electron microscope.Z Mikrosk Anat Forsch1975https://conductscience.org/library/papers/1224770PubMed
1023,737,439Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.J Bone Miner Res2013https://conductscience.org/library/papers/23737439PubMed

1 to 10 of 145

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Cited by319

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 431 citations.

PMIDTitleJournalYearIn PapersSource
42,965,168A proteomic roadmap of SaOS-2 osteoblast-to-osteocyte-like differentiation.Bone Rep2026https://conductscience.org/library/papers/42965168PubMed
42,936,451Bone remodeling in the absence of osteocytes.Bone Rep2026https://conductscience.org/library/papers/42936451PubMed
42,870,544S100A9 Induces RANKL Expression in Osteocytes Utilizing IL-6/sIL-6R Combination and gp130 Signaling Pathways.FASEB J2026https://conductscience.org/library/papers/42870544PubMed
42,858,168Postnatal development of bones and related hormonal factors in piglets.J Anim Sci2026https://conductscience.org/library/papers/42858168PubMed
42,823,204Future directions of osteoanabolic therapies in osteoporosis: Integrating current anabolic agents and emerging senescence-targeted strategies.Best Pract Res Clin Rheumatol2026https://conductscience.org/library/papers/42823204PubMed
42,761,784Chronic low-grade inflammation drives skeletal aging and neurocognitive decline: inflammaging as a central hub coupling bone-brain aging.Front Immunol2026https://conductscience.org/library/papers/42761784PubMed
42,757,471Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review).Mol Med Rep2026https://conductscience.org/library/papers/42757471PubMed
42,724,305Rethinking osteocyte models in vitro: the need for mineralised extracellular matrix and network architecture.Front Bioeng Biotechnol2026https://conductscience.org/library/papers/42724305PubMed
42,706,256Fibroblast growth factor receptor signaling in maturing osteoblasts controls cell-matrix interactions critical for osteocyte survival.Bone Res2026https://conductscience.org/library/papers/42706256PubMed
42,651,682Bone as a Biomarker of Ageing and Senescence: Connecting Musculoskeletal Health to Longevity via Diet, Nutrition and Exercise.Biology (Basel)2026https://conductscience.org/library/papers/42651682PubMed

1 to 10 of 319

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Genes18

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
BGLAP632PubTator's text mininghttps://conductscience.org/library/genes/632NCBI Gene
BTF3P11690PubTator's text mininghttps://conductscience.org/library/genes/690NCBI Gene
CA2760PubTator's text mininghttps://conductscience.org/library/genes/760NCBI Gene
CTSK1,513PubTator's text mininghttps://conductscience.org/library/genes/1513NCBI Gene
DKK122,943PubTator's text mininghttps://conductscience.org/library/genes/22943NCBI Gene
DMP11,758PubTator's text mininghttps://conductscience.org/library/genes/1758NCBI Gene
FGF238,074PubTator's text mininghttps://conductscience.org/library/genes/8074NCBI Gene
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630NCBI Gene
KL9,365PubTator's text mininghttps://conductscience.org/library/genes/9365NCBI Gene
MMP134,322PubTator's text mininghttps://conductscience.org/library/genes/4322NCBI Gene

1 to 10 of 18

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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