Paper · 34945755

Economic Evaluation of Universal Lynch Syndrome Screening Protocols among Newly Diagnosed Patients with Colorectal Cancer.

Hao J and 10 others. J Pers Med, 2021. Cited by 14 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Economic Evaluation of Universal Lynch Syndrome Screening Protocols among Newly Diagnosed Patients with Colorectal Cancer. Papers, record 34945755. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/34945755

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Economic Evaluation of Universal Lynch Syndrome Screening Protocols among Newly Diagnosed Patients with Colorectal Cancer.; PubMed
Journal: J Pers Med; PubMed
Year: 2021; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/34945755/; PubMed
DOI: https://doi.org/10.3390/jpm11121284; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC8708954/; PubMed
The journal: https://conductscience.org/library/journal-index/101602269; PubMed
Citations, by iCite: 14; iCite
Relative citation ratio, by iCite: 0.88; iCite
Revised in PubMed: 2022-03-29; PubMed

Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Hao J	Jing	https://orcid.org/0000-0001-9332-3842
2	Hassen D	Dina
3	Gudgeon JM	James M
4	Snyder SR	Susan R
5	Hampel H	Heather
6	Williams MS	Marc S	https://orcid.org/0000-0001-6165-8701
7	Sharaf RN	Ravi N
8	Lu CY	Christine Y
9	Williams JL	Janet L	https://orcid.org/0000-0002-4604-3933
10	Schlieder V	Victoria

1 to 10 of 11Source PubMed

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Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
R01 CA211723	NCI NIH HHS	United States	R01CA211723	PubMed and NIH
R01CA211723	NCI NIH HHS	United States	R01CA211723	PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References35

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	26,938,782	Cost-effectiveness of routine screening for Lynch syndrome in colorectal cancer patients up to 70 years of age.	Genet Med	2016	https://conductscience.org/library/papers/26938782	PubMed
2	22,658,618	ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing.	J Mol Diagn	2012	https://conductscience.org/library/papers/22658618	PubMed
3	29,300,371	Which Lynch syndrome screening programs could be implemented in the "real world"? A systematic review of economic evaluations.	Genet Med	2018	https://conductscience.org/library/papers/29300371	PubMed
4	26,028,255	PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.	N Engl J Med	2015	https://conductscience.org/library/papers/26028255	PubMed
5	31,130,287	Is immunohistochemistry-based screening for Lynch syndrome in endometrial cancer effective? The consent's the thing.	Gynecol Oncol	2019	https://conductscience.org/library/papers/31130287	PubMed
6	9,041,175	Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.	Cancer Res	1997	https://conductscience.org/library/papers/9041175	PubMed
7	15,544,708	Generalisability in economic evaluation studies in healthcare: a review and case studies.	Health Technol Assess	2004	https://conductscience.org/library/papers/15544708	PubMed
8	31,189,173	Generic Cost-Effectiveness Models: A Proof of Concept of a Tool for Informed Decision-Making for Public Health Precision Medicine.	Public Health Genomics	2018	https://conductscience.org/library/papers/31189173	PubMed
9	18,809,606	Feasibility of screening for Lynch syndrome among patients with colorectal cancer.	J Clin Oncol	2008	https://conductscience.org/library/papers/18809606	PubMed
10	20,084,010	The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer.	Genet Med	2010	https://conductscience.org/library/papers/20084010	PubMed

1 to 10 of 35

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Cited by11

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 14 citations.

PMID	Title	Journal	Year	In Papers	Source
42,958,100	A novel predictive model for DNA mismatch repair deficient colorectal carcinoma for cost-effective MMR testing in low-resource settings: HERALD-MMR (Histological Evaluation and Risk Assessment using Local Demographics for Mismatch Repair).	BMC Cancer	2026	https://conductscience.org/library/papers/42958100	PubMed
42,649,864	Universal Tumor Screening in Colorectal Cancer: Role of MMR Immunohistochemistry for Lynch Syndrome and Early-Onset CRC.	Cancers (Basel)	2026	https://conductscience.org/library/papers/42649864	PubMed
40,978,308	Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome): An Emerging Public Health Concern.	Health Sci Rep	2025	https://conductscience.org/library/papers/40978308	PubMed
40,315,972	Cost-effectiveness of Lynch Syndrome Screening in Colorectal Cancer: Universal Germline vs Sequential Screening.	Clin Gastroenterol Hepatol	2025	https://conductscience.org/library/papers/40315972	PubMed
40,172,779	The Cost Effectiveness of Genomic Medicine in Cancer Control: A Systematic Literature Review.	Appl Health Econ Health Policy	2025	https://conductscience.org/library/papers/40172779	PubMed
40,010,417	Cost-Effectiveness of Lynch Syndrome Identification Strategies in Individuals With Colorectal Cancer and the Impact on At-Risk Relatives.	Clin Gastroenterol Hepatol	2025	https://conductscience.org/library/papers/40010417	PubMed
37,978,552	"Go ahead and screen" - advice to healthcare systems for routine lynch syndrome screening from interviews with newly diagnosed colorectal cancer patients.	Hered Cancer Clin Pract	2023	https://conductscience.org/library/papers/37978552	PubMed
37,897,815	Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey.	JCO Precis Oncol	2023	https://conductscience.org/library/papers/37897815	PubMed
37,743,058	Comparison of immediate germline sequencing and multi-step screening for Lynch syndrome detection in high-risk endometrial and colorectal cancer patients.	J Gynecol Oncol	2024	https://conductscience.org/library/papers/37743058	PubMed
37,098,602	A picture is worth a thousand words: advancing the use of visualization tools in implementation science through process mapping and matrix heat mapping.	Implement Sci Commun	2023	https://conductscience.org/library/papers/37098602	PubMed

1 to 10 of 11

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Genes8

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
BRAF	673	PubTator's text mining	https://conductscience.org/library/genes/673	NCBI Gene
KRAS	3,845	PubTator's text mining	https://conductscience.org/library/genes/3845	NCBI Gene
MLH1	4,292	PubTator's text mining	https://conductscience.org/library/genes/4292	NCBI Gene
MSH2	4,436	PubTator's text mining	https://conductscience.org/library/genes/4436	NCBI Gene
MSH6	2,956	PubTator's text mining	https://conductscience.org/library/genes/2956	NCBI Gene
NRAS	4,893	PubTator's text mining	https://conductscience.org/library/genes/4893	NCBI Gene
PMS1	5,378	PubTator's text mining	https://conductscience.org/library/genes/5378	NCBI Gene
PMS2	5,395	PubTator's text mining	https://conductscience.org/library/genes/5395	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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