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Paper41756757

The Src inhibitor peptide TAT-Cx43266-283 improves survival in an intracranial murine model of lung cancer brain metastasis.

Cerveró-García P and 19 others. Neurooncol Adv, 2026. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The Src inhibitor peptide TAT-Cx43266-283 improves survival in an intracranial murine model of lung cancer brain metastasis. Papers, record 41756757. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41756757

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The Src inhibitor peptide TAT-Cx43266-283 improves survival in an intracranial murine model of lung cancer brain metastasis.
PubMed
Journal
Neurooncol Adv
PubMed
Year
2026
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
2
iCite
Revised in PubMed
2026-09-20
PubMed

Authors20

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Cerveró-García PPilarhttps://orcid.org/0000-0002-9812-9384
2Jiménez-Madrona EEnriquehttps://orcid.org/0000-0002-9943-3564
3Álvarez-Vázquez AAndreahttps://orcid.org/0000-0002-8626-8926
4Flores-Hernández RRaquelhttps://orcid.org/0000-0003-4697-5180
5García-Vicente LLaurahttps://orcid.org/0000-0001-8746-1050
6García-Guerrero LLaurahttps://orcid.org/0009-0008-3447-4104
7Alonso-Amador JJJuan Joséhttps://orcid.org/0009-0001-2367-6084
8González-Sánchez RRaúlhttps://orcid.org/0009-0003-5219-7490
9Ollauri-Ibáñez CClaudiahttps://orcid.org/0000-0002-7319-4913
10Paniagua-Sancho MMaríahttps://orcid.org/0000-0001-6981-4510
11Talaverón RRocíohttps://orcid.org/0000-0002-5068-9171
12Rodrigues-Teixeira TTelmohttps://orcid.org/0000-0002-3826-0997
13Martín-Guerrero SMSandra Mhttps://orcid.org/0000-0003-1489-4757
14Casado PPedrohttps://orcid.org/0000-0002-4207-9349
15Rajeeve VVinothinihttps://orcid.org/0000-0002-6361-4291
16Shields TTommyhttps://orcid.org/0009-0000-4198-3953
17Hijazi MMaruanhttps://orcid.org/0000-0003-0861-7577
18Cutillas PRPedro Rhttps://orcid.org/0000-0002-3426-2274
19Jaraíz-Rodríguez MMyriamhttps://orcid.org/0000-0002-9908-3541
20Tabernero AArantxahttps://orcid.org/0000-0001-6302-6134

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

References67

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
126,669,454Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype.Nat Commun2015https://conductscience.org/library/papers/26669454PubMed
228,712,848A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK.Stem Cell Reports2017https://conductscience.org/library/papers/28712848PubMed
331,780,762Bevacizumab for the treatment of non-small cell lung cancer patients with synchronous brain metastases.Sci Rep2019https://conductscience.org/library/papers/31780762PubMed
423,009,336EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer.Mol Cancer2012https://conductscience.org/library/papers/23009336PubMed
512,884,910Src family kinases in tumor progression and metastasis.Cancer Metastasis Rev2003https://conductscience.org/library/papers/12884910PubMed
633,238,452Connexin43 Region 266-283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation.Int J Mol Sci2020https://conductscience.org/library/papers/33238452PubMed
734,503,072Impairment of Autophagic Flux Participates in the Antitumor Effects of TAT-Cx43266-283 in Glioblastoma Stem Cells.Cancers (Basel)2021https://conductscience.org/library/papers/34503072PubMed
811,114,744Role of Src expression and activation in human cancer.Oncogene2000https://conductscience.org/library/papers/11114744PubMed
934,932,393Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.J Clin Oncol2022https://conductscience.org/library/papers/34932393PubMed
1037,210,176Systemic Treatment for Brain Metastases in NSCLC: A New Chapter.J Thorac Oncol2023https://conductscience.org/library/papers/37210176PubMed
1124,457,967A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype.Cell Death Dis2014https://conductscience.org/library/papers/24457967PubMed
1238,876,188A proteomic approach supports the clinical relevance of TAT-Cx43266-283 in glioblastoma.Transl Res2024https://conductscience.org/library/papers/38876188PubMed
1327,391,443Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes.Oncotarget2016https://conductscience.org/library/papers/27391443PubMed
1440,595,567Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis.Nat Commun2025https://conductscience.org/library/papers/40595567PubMed
1529,440,631Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity.Cell Death Dis2018https://conductscience.org/library/papers/29440631PubMed
1621,468,047Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer.Br J Cancer2011https://conductscience.org/library/papers/21468047PubMed
1729,526,531Non-small-cell Lung Cancer With Brain Metastasis at Presentation.Clin Lung Cancer2018https://conductscience.org/library/papers/29526531PubMed
1831,883,012Connexin43 peptide, TAT-Cx43266-283, selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo.Neuro Oncol2020https://conductscience.org/library/papers/31883012PubMed
1917,913,584TAT transduction: the molecular mechanism and therapeutic prospects.Trends Mol Med2007https://conductscience.org/library/papers/17913584PubMed
2018,388,349Src as a potential therapeutic target in non-small-cell lung cancer.Ann Oncol2008https://conductscience.org/library/papers/18388349PubMed

See all 67 references

Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMIDTitleJournalYearIn Papers
42,667,630Advanced Materials for Biologics Delivery to Brain Tumors.Adv Mater2026https://conductscience.org/library/papers/42667630

Source PubMed

Genes34

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ALK238PubTator's text mininghttps://conductscience.org/library/genes/238NCBI Gene
ANKS1A23,294PubTator's text mininghttps://conductscience.org/library/genes/23294NCBI Gene
ARHGEF29,181PubTator's text mininghttps://conductscience.org/library/genes/9181NCBI Gene
CCNE29,134PubTator's text mininghttps://conductscience.org/library/genes/9134NCBI Gene
CD27429,126PubTator's text mininghttps://conductscience.org/library/genes/29126NCBI Gene
CDK1983PubTator's text mininghttps://conductscience.org/library/genes/983NCBI Gene
CIAPIN157,019PubTator's text mininghttps://conductscience.org/library/genes/57019NCBI Gene
CSNK2A11,457PubTator's text mininghttps://conductscience.org/library/genes/1457NCBI Gene
DYNC1LI151,143PubTator's text mininghttps://conductscience.org/library/genes/51143NCBI Gene
EGF1,950PubTator's text mininghttps://conductscience.org/library/genes/1950NCBI Gene
EGFR1,956PubTator's text mininghttps://conductscience.org/library/genes/1956NCBI Gene
EPB41L22,037PubTator's text mininghttps://conductscience.org/library/genes/2037NCBI Gene
FGF22,247PubTator's text mininghttps://conductscience.org/library/genes/2247NCBI Gene
FMNL1752PubTator's text mininghttps://conductscience.org/library/genes/752NCBI Gene
GJA12,697PubTator's text mininghttps://conductscience.org/library/genes/2697NCBI Gene
HSPA12B116,835PubTator's text mininghttps://conductscience.org/library/genes/116835NCBI Gene
IQSEC223,096PubTator's text mininghttps://conductscience.org/library/genes/23096NCBI Gene
KRAS3,845PubTator's text mininghttps://conductscience.org/library/genes/3845NCBI Gene
MAP2K15,604PubTator's text mininghttps://conductscience.org/library/genes/5604NCBI Gene
MAP2K75,609PubTator's text mininghttps://conductscience.org/library/genes/5609NCBI Gene

See all 34 genes

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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