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Drug · CHEMBL710

FINASTERIDE

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. FINASTERIDE. Drugs and targets, record CHEMBL710. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL710

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
FINASTERIDE
ChEMBL
ChEMBL ID
CHEMBL710
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Aindeem, Finasteride component of entadfi, Propecia, Proscar, Prostide
ChEMBL
Other names
Finasterida, MK-906, NSC-741485, NSC-759318
ChEMBL
DrugBank
DB01216
DrugBank
InChIKey
DBEPLOCGEIEOCV-WSBQPABSSA-N
ChEMBL
Open Targets' highest stage
Approval, for 4 of its 12 diseases, from ATC, DailyMed and TTD
Open Targets

Targets1

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

TargetProteinMechanismActionGene in Genes
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase 2Steroid 5-alpha-reductase 2 inhibitorINHIBITORhttps://conductscience.org/library/genes/6716

Source ChEMBL

Diseases12

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
androgenetic alopeciaApprovalDailyMed2812https://conductscience.org/library/drugs?q=MONDO_0005339
benign prostatic hyperplasiaApprovalATC, DailyMed and TTD5111https://conductscience.org/library/drugs?q=MONDO_0010811
prostate cancerPhase 2/3ClinicalTrials.gov66https://conductscience.org/library/drugs?q=MONDO_0008315
central serous retinopathyPhase 2ClinicalTrials.gov33https://conductscience.org/library/drugs?q=EFO_0009784
hypogonadismPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0002146
HematuriaPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0000790
HirsutismUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001007
acnePhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0011438
lower urinary tract symptomPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_0008008
non-small cell lung carcinomaPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005233

Trials65

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT01231607Dutasteride Versus Placebo and Finasteride in Men With Androgenetic AlopeciaPhase 39172012-10-04finasterideIts nameClinicalTrials.gov
NCT01139762A Study of Tadalafil Use With Finasteride in Men With Enlarged Prostates and Urinary SymptomsPhase 36962013-02-27finasterideIts nameClinicalTrials.gov
NCT03004469Study to Evaluate the Efficacy and Safety of P-3074 Topical Solution in the Treatment of Androgenetic AlopeciaPhase 34582019-04-19finasterideIts nameClinicalTrials.gov
NCT012966723 Month Finasteride Challenge Test Can Significantly Improve the Performance of Screening for Prostate CancerPhase 43832017-09-08finasterideIts nameClinicalTrials.gov
NCT00438464Finasteride in Treating Patients With Stage II Prostate Cancer Who Are Undergoing SurgeryPhase 22042016-03-09finasterideIts nameClinicalTrials.gov
NCT01342367Feasibility of Hormones and Radiation for Intermediate or High Risk Prostate Cancer742021-10-28finasterideIts nameClinicalTrials.gov
NCT004755015-Alpha Reductase and Anabolic Effects of TestosteronePhase 2602014-07-31finasterideIts nameClinicalTrials.gov
NCT00736645Selenomethionine and Finasteride Before Surgery or Radiation Therapy in Treating Patients With Stage I or Stage II Prostate CancerPhase 2552017-11-28finasterideIts nameClinicalTrials.gov
NCT02213107Enzalutamide & Dutasteride/Finasteride as 1st Line Treatment for Patients =/> 65 Years Old With Prostate Cancer.Phase 2432024-11-13finasterideIts nameClinicalTrials.gov
NCT02248701Testosterone Plus Finasteride Treatment After Spinal Cord InjuryPhase 2332023-09-29finasterideIts nameClinicalTrials.gov

1 to 10 of 65

See all 65 trials

Comparisons in its trials23

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
5ARI Users vs Non 5ARI Users: Suicide (Based on Administrative Data Elements From Ontario Registrar General Death Database, National Ambulatory Care Reporting System, Hospital Discharge Abstracts, and Ontario Regional Mental Health Database)
38 of 93,19736 of 93,197186,394NCT02876757Trial comparisons
5ARI Users vs Non 5ARI Users: deaths from any cause160 of 93,197139 of 93,197186,394NCT02876757Trial comparisons
5ARI Users vs Non 5ARI Users: Suicide Attempt (Based on Administrative Data Elements From National Ambulatory Care Reporting System, and Ontario Regional Mental Health Database)169 of 93,197130 of 93,197186,394NCT02876757Trial comparisons
5ARI Users vs Non 5ARI Users: serious adverse events0 of 93,1970 of 93,197186,394NCT02876757Trial comparisons
5ARI Users vs Non 5ARI Users: Depression (Based on Administrative Data Elements From Hospital Discharge Abstract Database, and Ontario Regional Mental Health Database and Ontario Health Insurance Plan)
1,750 of 89,8441,231 of 89,844179,688NCT02876757Trial comparisons
Finasteride vs Placebo: deaths from any cause0 of 3060 of 77383NCT01296672Trial comparisons
Finasteride vs Placebo: serious adverse events3 of 3061 of 77383NCT01296672Trial comparisons
Arm I (Finasteride) vs Arm II (Placebo): serious adverse events0 of 890 of 94183NCT00438464Trial comparisons
SOC Cohort vs Oral ADT Group: deaths from any cause8 of 307 of 4070NCT01342367Trial comparisons
SOC Cohort vs Oral ADT Group: serious adverse events2 of 302 of 4070NCT01342367Trial comparisons

Papers from its trials18

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
34709067RESULT1PubMed
32969781RESULT1PubMed
24326421RESULT1PubMed
24012740RESULT1PubMed
21273946RESULT1PubMed
20969601RESULT1PubMed
17196507RESULT1PubMed
14681504RESULT1PubMed
12689743RESULT1PubMed
11796283RESULT1PubMed

Tests in its trials3

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

TestTrials naming it as an outcomeAs a primary outcomeSource
Complex Figure Copy and Recall10ConductCognition
Line Angle Matching10ConductCognition
Trail Making Test A10ConductCognition

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL710

GET https://conductscience.org/api/drugs/v1/CHEMBL710/trials?page=2