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Paper · 24612866

Calcium signaling and the secretory activity of bile duct epithelia.

Amaya MJ and 1 other. Cell Calcium, 2014. Cited by 16 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Calcium signaling and the secretory activity of bile duct epithelia. Papers, record 24612866. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/24612866

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Calcium signaling and the secretory activity of bile duct epithelia.
PubMed
Journal
Cell Calcium
PubMed
Year
2014
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Review
PubMed
Citations, by iCite
16
iCite
Relative citation ratio, by iCite
0.47
iCite
Revised in PubMed
2021-10-21
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Amaya MJMaria Jimena
2Nathanson MHMichael H

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Bile DuctsMajor topic
Calcium SignalingMajor topic
Epithelial CellsMajor topic
Calcium
Cholestasis
Humans
Inositol 1,4,5-Trisphosphate Receptors
Receptors, Cytoplasmic and Nuclear

Source PubMed

Grants9

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 DK061747NIDDK NIH HHSUnited StatesR01DK061747PubMed and NIHNIH RePORTER
R01 DK045710NIDDK NIH HHSUnited StatesR01DK045710PubMed and NIHNIH RePORTER
P01 DK057751NIDDK NIH HHSUnited StatesP01DK057751PubMed and NIHNIH RePORTER
P30 DK034989NIDDK NIH HHSUnited StatesP30DK034989PubMed and NIHNIH RePORTER
DK57751NIDDK NIH HHSUnited StatesP01DK057751PubMed and NIHNIH RePORTER
DK34989NIDDK NIH HHSUnited StatesP30DK034989PubMed and NIHNIH RePORTER
DK45710NIDDK NIH HHSUnited StatesR01DK045710PubMed and NIHNIH RePORTER
DK61747NIDDK NIH HHSUnited StatesR01DK061747PubMed and NIHNIH RePORTER
R29DK045710NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References89

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
110,866,953Regulation of the type III InsP(3) receptor by InsP(3) and ATP.Biophys J2000https://conductscience.org/library/papers/10866953PubMed
223,839,970The insulin receptor translocates to the nucleus to regulate cell proliferation in liver.Hepatology2014https://conductscience.org/library/papers/23839970PubMed
321,274,883Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1.Hepatology2011https://conductscience.org/library/papers/21274883PubMed
418,388,137Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl- transport in biliary epithelial cells through a PKCzeta-dependent pathway.J Physiol2008https://conductscience.org/library/papers/18388137PubMed
511,487,549Bile duct epithelia regulate biliary bicarbonate excretion in normal rat liver.Gastroenterology2001https://conductscience.org/library/papers/11487549PubMed
616,952,559Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling.Gastroenterology2006https://conductscience.org/library/papers/16952559PubMed
78,918,898Subtype-specific expression patterns of inositol 1,4,5-trisphosphate receptors in rat airway epithelial cells.J Histochem Cytochem1996https://conductscience.org/library/papers/8918898PubMed
815,336,978The role of inositol 1,4,5-trisphosphate receptors in the regulation of bile secretion in health and disease.Biochem Biophys Res Commun2004https://conductscience.org/library/papers/15336978PubMed
916,973,607Ryanodine receptors in liver.J Biol Chem2006https://conductscience.org/library/papers/16973607PubMed
1018,073,207c-Met must translocate to the nucleus to initiate calcium signals.J Biol Chem2008https://conductscience.org/library/papers/18073207PubMed

1 to 10 of 89

See all 89 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 16 citations.

PMIDTitleJournalYearIn PapersSource
42,825,310βKlotho filters ligand-independent FGFR1/4-PLCγ signaling to prevent aberrant constitutive Ca2+ entry.Korean J Physiol Pharmacol2026https://conductscience.org/library/papers/42825310PubMed
34,764,255Generation of functional ciliated cholangiocytes from human pluripotent stem cells.Nat Commun2021https://conductscience.org/library/papers/34764255PubMed
30,563,259Calcium Signaling in Cholangiocytes: Methods, Mechanisms, and Effects.Int J Mol Sci2018https://conductscience.org/library/papers/30563259PubMed
30,023,358Calcium Signaling in Liver Injury and Regeneration.Front Med (Lausanne)2018https://conductscience.org/library/papers/30023358PubMed
29,642,457Dandelion Root Extract Induces Intracellular Ca2+ Increases in HEK293 Cells.Int J Mol Sci2018https://conductscience.org/library/papers/29642457PubMed
26,100,660Calcium signaling and secretion in cholangiocytes.Pancreatology2015https://conductscience.org/library/papers/26100660PubMed
25,437,447Apical localization of inositol 1,4,5-trisphosphate receptors is independent of extended synaptotagmins in hepatocytes.PLoS One2014https://conductscience.org/library/papers/25437447PubMed
25,066,674Calcium signaling in cilia and ciliary-mediated intracellular calcium signaling: are they independent or coordinated molecular events?Hepatology2014https://conductscience.org/library/papers/25066674PubMed

Genes22

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ABCB118,647PubTator's text mininghttps://conductscience.org/library/genes/8647NCBI Gene
ABCC21,244PubTator's text mininghttps://conductscience.org/library/genes/1244NCBI Gene
ANO155,107PubTator's text mininghttps://conductscience.org/library/genes/55107NCBI Gene
CAMK18,536PubTator's text mininghttps://conductscience.org/library/genes/8536NCBI Gene
CFTR1,080PubTator's text mininghttps://conductscience.org/library/genes/1080NCBI Gene
CREB11,385PubTator's text mininghttps://conductscience.org/library/genes/1385NCBI Gene
DRD21,813PubTator's text mininghttps://conductscience.org/library/genes/1813NCBI Gene
GJA12,697PubTator's text mininghttps://conductscience.org/library/genes/2697NCBI Gene
GJB12,705PubTator's text mininghttps://conductscience.org/library/genes/2705NCBI Gene
IL43,565PubTator's text mininghttps://conductscience.org/library/genes/3565NCBI Gene

1 to 10 of 22

See all 22 genes

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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