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Disease · MONDO_0006883

malignant superior sulcus neoplasm

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. malignant superior sulcus neoplasm. Diseases, record MONDO_0006883. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0006883

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
malignant superior sulcus neoplasm
Open Targets
Open Targets ID
MONDO_0006883
Open Targets
Other names
Pancoast tumor, Pancoast's tumor, Pancoast's tumour, malignant Superior sulcus lung neoplasm, malignant Superior sulcus lung tumor, malignant Superior sulcus lung tumour, malignant Superior sulcus neoplasm of lung, malignant Superior sulcus neoplasm of the lung, malignant Superior sulcus tumor, malignant Superior sulcus tumor of lung, malignant Superior sulcus tumor of the lung, malignant Superior sulcus tumour of lung, malignant Superior sulcus tumour of the lung, malignant pulmonary sulcus neoplasm, pulmonary sulcus neoplasm, malignant, superior pulmonary sulcus syndrome
Open Targets
Disease Ontology
DOID:8007
Disease Ontology
NCI Thesaurus
C7527
NCI Thesaurus
Highest stage of its drugs
Phase 3, for 1 of its 9 drugs, from ClinicalTrials.gov
Open Targets

Drugs9

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
DURVALUMABCHEMBL3301587AntibodyPhase 3ClinicalTrials.gov111Drugs and targets
CISPLATINCHEMBL11359Small moleculePhase 2ClinicalTrials.gov222Drugs and targets
CARBOPLATINCHEMBL1351Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
DOCETAXELCHEMBL3545252Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
ETOPOSIDECHEMBL44657Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
MITOMYCINCHEMBL105Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
NIVOLUMABCHEMBL2108738AntibodyPhase 2ClinicalTrials.gov111Drugs and targets
PACLITAXELCHEMBL428647Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
VINDESINECHEMBL238071Small moleculePhase 2ClinicalTrials.gov111Drugs and targets

Targets19

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
TUBA1ATubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/7846Drugs and targets
TUBA1BTubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/10376Drugs and targets
TUBA1CTubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/84790Drugs and targets
TUBA3CTubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/7278Drugs and targets
TUBA3ETubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/112714Drugs and targets
TUBA4ATubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/7277Drugs and targets
TUBBTubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/203068Drugs and targets
TUBB1Tubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/81027Drugs and targets
TUBB2ATubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/7280Drugs and targets
TUBB2BTubulin2Tubulin inhibitorPhase 2https://conductscience.org/library/genes/347733Drugs and targets

1 to 10 of 19

See all 19 targets

Trials4

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00062439S0220: Chemoradiotherapy Followed By Surgery and Docetaxel in Treating Patients With Pancoast TumorsPhase 2462013-11-25Lung CancerCISPLATIN, DOCETAXEL, ETOPOSIDEOpen Targets' reading of its recordClinicalTrials.gov
NCT04465968Efficacy and Safety of CRT, Durvalumab and Surgery for SSTPhase 384Superior Sulcus Tumor, Non-small Cell Lung Cancer Stage IIB, Non Small Cell Lung Cancer Stage IIIDURVALUMABOpen Targets' reading of its recordClinicalTrials.gov
NCT00128037Trial of Pre-operative Chemoradiotherapy Followed by Surgical Resection in Pancoast Tumors (JCOG 9806)Phase 275Pulmonary NeoplasmCISPLATIN, MITOMYCIN, VINDESINEOpen Targets' reading of its recordClinicalTrials.gov
NCT05684276DUMAS: Neo-Adjuvant Immunotherapy for Pancoast TumorsPhase 222NSCLC, Pancoast TumorCARBOPLATIN, NIVOLUMAB, PACLITAXELIts record names the diseaseClinicalTrials.gov

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

None in this release.

Papers from its trials0

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0006883

GET https://conductscience.org/api/diseases/v1/MONDO_0006883/drugs