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Disease · MONDO_0019056

neuromuscular disease

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. neuromuscular disease. Diseases, record MONDO_0019056. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0019056

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
neuromuscular disease
Open Targets
Open Targets ID
MONDO_0019056
Open Targets
Other names
nerve and muscle disorder
Open Targets
Disease Ontology
DOID:440
Disease Ontology
MeSH
D009468
MeSH
Orphanet
ORPHA:68381
Orphanet
Highest stage of its drugs
Approval, for 1 of its 3 drugs, from EMA Human Drugs
Open Targets

Drugs3

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
AMIFAMPRIDINECHEMBL354077Small moleculeApprovalEMA Human Drugs100Drugs and targets
SODIUM CHLORIDECHEMBL1200574Small moleculeUnknownClinicalTrials.gov111Drugs and targets
ZIDOVUDINECHEMBL129Small moleculeUnknownClinicalTrials.gov111Drugs and targets

Targets40

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
KCNA1Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3736Drugs and targets
KCNA10Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3744Drugs and targets
KCNA2Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3737Drugs and targets
KCNA3Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3738Drugs and targets
KCNA4Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3739Drugs and targets
KCNA5Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3741Drugs and targets
KCNA6Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3742Drugs and targets
KCNA7Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3743Drugs and targets
KCNB1Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/3745Drugs and targets
KCNB2Voltage-gated potassium channel1Voltage-gated potassium channel blockerApprovalhttps://conductscience.org/library/genes/9312Drugs and targets

1 to 10 of 40

See all 40 targets

Trials2

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT03623698Nebulised Hypertonic Saline in Children and Young People With Neuromuscular Disease and Cerebral Palsy242020-09-16Neuromuscular DiseasesSODIUM CHLORIDEIts record names the diseaseClinicalTrials.gov
NCT00002044A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular DiseasesNot applicableAIDS Dementia Complex, Neuromuscular Diseases, HIV InfectionsZIDOVUDINEOpen Targets' reading of its recordClinicalTrials.gov

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

None in this release.

Papers from its trials1

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing it
33184120DERIVED1

Source PubMed

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0019056

GET https://conductscience.org/api/diseases/v1/MONDO_0019056/targets?page=2

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