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Paper · 32073014

Glycyrrhizin inhibits osteoarthritis development through suppressing the PI3K/AKT/NF-κB signaling pathway in vivo and in vitro.

Jiang RH and 6 others. Food Funct, 2020. Cited by 40 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Glycyrrhizin inhibits osteoarthritis development through suppressing the PI3K/AKT/NF-κB signaling pathway in vivo and in vitro. Papers, record 32073014. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/32073014

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Glycyrrhizin inhibits osteoarthritis development through suppressing the PI3K/AKT/NF-κB signaling pathway in vivo and in vitro.
PubMed
Journal
Food Funct
PubMed
Year
2020
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
40
iCite
Relative citation ratio, by iCite
2.78
iCite
Revised in PubMed
2026-01-27
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Jiang RHRen-Hao
2Xu JJJia-Jing
3Zhu DCDing-Chao
4Li JFJia-Feng
5Zhang CXChen-Xi
6Lin NNan
7Gao WYWei-Yang

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ChondrocytesMajor topic
Glycyrrhizic AcidMajor topic
NF-kappa BMajor topic
Phosphatidylinositol 3-KinasesMajor topic
Proto-Oncogene Proteins c-aktMajor topic
Animals
Cells, Cultured
Cytokines
Gene Expression Regulation
Humans
Interleukin-1beta
Male
Mice
Molecular Structure
Nitric Oxide
Phosphorylation
Signal Transduction

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by25

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 40 citations.

PMIDTitleJournalYearIn PapersSource
42,885,282Glycyrrhizic acid attenuates corneal inflammation and pathological angiogenesis through FAK/PI3K/AKT signaling.Mol Med Rep2026https://conductscience.org/library/papers/42885282PubMed
42,582,610Oyster hydrolysate attenuates osteoarthritis progression by modulating inflammatory signaling and extracellular matrix homeostasis.Nutr Res Pract2026https://conductscience.org/library/papers/42582610PubMed
42,371,378Bioactive compounds of Glycyrrhiza glabra and their functional role in modulating gut inflammation and intestinal homeostasis.Inflammopharmacology2026https://conductscience.org/library/papers/42371378PubMed
41,789,596Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review).Mol Med Rep2026https://conductscience.org/library/papers/41789596PubMed
41,705,157Mechanistic insights into non-coding RNAs regulate autophagy in chondrocytes and their contribution to osteoarthritis.Front Med (Lausanne)2025https://conductscience.org/library/papers/41705157PubMed
41,463,300Emerging Role of Calycosin in Inflammatory Diseases: Molecular Mechanisms and Potential Therapeutic Applications.Biomolecules2025https://conductscience.org/library/papers/41463300PubMed
40,137,300Investigating the Mechanism of Action of Ipomoea pes-caprae in the Treatment of Rheumatoid Arthritis Based on Serum Metabolomics and Network Pharmacology.Mar Drugs2025https://conductscience.org/library/papers/40137300PubMed
40,012,623The dual anti-inflammatory and anticoagulant effects of Jianpi Huashi Tongluo prescription on Rheumatoid Arthritis through inhibiting the activation of the PI3K/AKT signaling pathway.Front Pharmacol2025https://conductscience.org/library/papers/40012623PubMed
39,606,009Understanding the impact of diabetes on bone health: A clinical review.Metabol Open2024https://conductscience.org/library/papers/39606009PubMed
39,376,558Regulating the lncRNA DSCR9/RPLP2/PI3K/AKT axis: an important mechanism of Xinfeng capsules in improving rheumatoid arthritis.Front Immunol2024https://conductscience.org/library/papers/39376558PubMed

1 to 10 of 25

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Genes11

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ACAN176PubTator's text mininghttps://conductscience.org/library/genes/176NCBI Gene
ADAMTS511,096PubTator's text mininghttps://conductscience.org/library/genes/11096NCBI Gene
AKT1207PubTator's text mininghttps://conductscience.org/library/genes/207NCBI Gene
IL1B3,553PubTator's text mininghttps://conductscience.org/library/genes/3553NCBI Gene
IL63,569PubTator's text mininghttps://conductscience.org/library/genes/3569NCBI Gene
MMP134,322PubTator's text mininghttps://conductscience.org/library/genes/4322NCBI Gene
MMP34,314PubTator's text mininghttps://conductscience.org/library/genes/4314NCBI Gene
NFKB14,790PubTator's text mininghttps://conductscience.org/library/genes/4790NCBI Gene
NOS24,843PubTator's text mininghttps://conductscience.org/library/genes/4843NCBI Gene
PTGS25,743PubTator's text mininghttps://conductscience.org/library/genes/5743NCBI Gene

1 to 10 of 11

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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