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Paper36977989

p20BAP31 induces cell apoptosis via both AIF caspase-independent and the ROS/JNK mitochondrial pathway in colorectal cancer.

Jiang X and 6 others. Cell Mol Biol Lett, 2023. Cited by 34 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. p20BAP31 induces cell apoptosis via both AIF caspase-independent and the ROS/JNK mitochondrial pathway in colorectal cancer. Papers, record 36977989. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36977989

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
p20BAP31 induces cell apoptosis via both AIF caspase-independent and the ROS/JNK mitochondrial pathway in colorectal cancer.
PubMed
Journal
Cell Mol Biol Lett
PubMed
Year
2023
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
34
iCite
Relative citation ratio, by iCite
3.35
iCite
Revised in PubMed
2026-01-27
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Jiang XXiaohan
2Li GGuoxun
3Zhu BBenzhi
4Zang JJingnan
5Lan TTian
6Jiang RRui
7Wang BBing

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CaspasesMajor topic
Colorectal NeoplasmsMajor topic
Humans
Apoptosis
Apoptosis Inducing Factor
Cell Line, Tumor
JNK Mitogen-Activated Protein Kinases
MAP Kinase Signaling System
Membrane Potential, Mitochondrial
Mitochondria
Reactive Oxygen Species
Membrane Proteins

Source PubMed

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
XLYC1902063Liaoning Revitalization Talents ProgramPubMed
2020JH2/10300080Key Research and Development Program of Jiangxi ProvincePubMed
31670770National Natural Science Foundation of ChinaPubMed
2016YFC1302402National Natural Science Foundation of ChinaPubMed
31370784National Natural Science Foundation of ChinaPubMed
N2120004Support Program for Longyuan Youth and Fundamental Research Funds for the Universities of Gansu ProvincePubMed

Source PubMed

References63

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
117,562,483Apoptosis: a review of programmed cell death.Toxicol Pathol2007https://conductscience.org/library/papers/17562483PubMed
217,056,546Bap31 enhances the endoplasmic reticulum export and quality control of human class I MHC molecules.J Immunol2006https://conductscience.org/library/papers/17056546PubMed
312,408,857Dueling activities of AIF in cell death versus survival: DNA binding and redox activity.Cell2002https://conductscience.org/library/papers/12408857PubMed
419,603,101Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs.Mol Med2009https://conductscience.org/library/papers/19603101PubMed
527,646,922Activation of apoptosis signalling pathways by reactive oxygen species.Biochim Biophys Acta2016https://conductscience.org/library/papers/27646922PubMed
615,315,760Mouse development and cell proliferation in the absence of D-cyclins.Cell2004https://conductscience.org/library/papers/15315760PubMed
721,666,810Physiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein kinase.World J Biol Chem2011https://conductscience.org/library/papers/21666810PubMed
823,877,564Control of cell cycle transcription during G1 and S phases.Nat Rev Mol Cell Biol2013https://conductscience.org/library/papers/23877564PubMed
915,294,914Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils.J Biol Chem2004https://conductscience.org/library/papers/15294914PubMed
1028,333,124BAP31 is involved in T cell activation through TCR signal pathways.Sci Rep2017https://conductscience.org/library/papers/28333124PubMed
1111,121,041An alternative, nonapoptotic form of programmed cell death.Proc Natl Acad Sci U S A2000https://conductscience.org/library/papers/11121041PubMed
1221,147,274Tight control of mitochondrial membrane potential by cytochrome c oxidase.Mitochondrion2011https://conductscience.org/library/papers/21147274PubMed
1322,175,013Mitochondria-ros crosstalk in the control of cell death and aging.J Signal Transduct2012https://conductscience.org/library/papers/22175013PubMed
149,334,338p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum.J Cell Biol1997https://conductscience.org/library/papers/9334338PubMed
1512,529,377Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria.J Biol Chem2003https://conductscience.org/library/papers/12529377PubMed
1622,510,572Pattern of cellular quiescence over the hibernation cycle in liver of thirteen-lined ground squirrels.Cell Cycle2012https://conductscience.org/library/papers/22510572PubMed
179,396,746Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31.J Cell Biol1997https://conductscience.org/library/papers/9396746PubMed
1831,734,898Induction of growth cessation by acacetin via β-catenin pathway and apoptosis by apoptosis inducing factor activation in colorectal carcinoma cells.Mol Biol Rep2020https://conductscience.org/library/papers/31734898PubMed
1917,237,344Mitochondrial membrane permeabilization in cell death.Physiol Rev2007https://conductscience.org/library/papers/17237344PubMed
2022,197,342Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31.Biochim Biophys Acta2012https://conductscience.org/library/papers/22197342PubMed

See all 63 references

Cited by26

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 34 citations.

PMIDTitleJournalYearIn PapersSource
42,882,463BAP31 Facilitates TGF-β Trafficking and Secretion and Promotes Dendritic Cell Dysfunction in Cervical Cancer.Cells2026https://conductscience.org/library/papers/42882463PubMed
42,378,815Mechanisms and advances of drug resistance in colorectal cancer: A systematic overview of multi-layered regulatory networks.Transl Oncol2026https://conductscience.org/library/papers/42378815PubMed
42,374,476Targeting AIF to trigger RIPKs/MLKL necroptosis: a disulfiram-based strategy to reverse paclitaxel resistance in ovarian cancer.Cell Commun Signal2026https://conductscience.org/library/papers/42374476PubMed
42,261,393Evaluation and investigation of the cardiotoxicity of the potential anti-cholangiocarcinoma drug lanatoside C.Front Toxicol2026https://conductscience.org/library/papers/42261393PubMed
42,121,913Terahertz Waves Trigger Apoptosis in Cutaneous Squamous Cell Carcinoma via Apoptosis-Inducing Factor Mediated Mitochondrial Pathway.Cells2026https://conductscience.org/library/papers/42121913PubMed
42,072,315Tri- and Difluoromethylated Spiro[5.5]trienones Inhibit the Growth of Cancer Cells In Vitro and In Vivo.Biomedicines2026https://conductscience.org/library/papers/42072315PubMed
41,963,300Mechanism and therapeutic significance of ARV-110 combined with a PDGFR inhibitor for the induction of apoptosis in castration-resistant prostate cancer cells through the ROS/JNK pathway.Cell Death Dis2026https://conductscience.org/library/papers/41963300PubMed
41,935,069Organelle contact sites in cancer cells.Cell Death Dis2026https://conductscience.org/library/papers/41935069PubMed
41,898,493Liposomal Vitamin C as a Modulator of the Efficacy of Ceralasertib Therapy in Ovarian Cancer.Int J Mol Sci2026https://conductscience.org/library/papers/41898493PubMed
41,767,393Endoplasmic reticulum stress in skeletal muscle dysfunction of type 2 diabetes: mechanisms and therapeutic implications.Front Endocrinol (Lausanne)2026https://conductscience.org/library/papers/41767393PubMed
41,039,188Programmed cell death in triple-negative breast cancer.Cell Mol Biol Lett2025https://conductscience.org/library/papers/41039188PubMed
40,918,364Phosphorus(V) Tris(ethoxycarbonyl)corrole As a Safe and Effective Photosensitizer for Hepatocellular Carcinoma Treatment in Zebrafish Xenograft Models.ACS Omega2025https://conductscience.org/library/papers/40918364PubMed
40,841,819PANoptosis in cancer: molecular mechanisms and therapeutic potential.Cancer Gene Ther2025https://conductscience.org/library/papers/40841819PubMed
40,547,309Mito-fission gene prognostic model for colorectal cancer.PeerJ2025https://conductscience.org/library/papers/40547309PubMed
40,110,122Natural products modulating MAPK for CRC treatment: a promising strategy.Front Pharmacol2025https://conductscience.org/library/papers/40110122PubMed
39,850,563Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells.Front Pharmacol2024https://conductscience.org/library/papers/39850563PubMed
39,736,624Transcriptome analysis reveals the anticancer effects of fenbendazole on ovarian cancer: an in vitro and in vivo study.BMC Cancer2024https://conductscience.org/library/papers/39736624PubMed
39,655,191Unleashing of cytotoxic effects of thymoquinone-bovine serum albumin nanoparticles on A549 lung cancer cells.Open Life Sci2024https://conductscience.org/library/papers/39655191PubMed
39,518,966Ginsenoside Rg3 Improved Age-Related Macular Degeneration Through Inhibiting ROS-Mediated Mitochondrion-Dependent Apoptosis In Vivo and In Vitro.Int J Mol Sci2024https://conductscience.org/library/papers/39518966PubMed
39,379,817Caspase-8 in inflammatory diseases: a potential therapeutic target.Cell Mol Biol Lett2024https://conductscience.org/library/papers/39379817PubMed

See all 26 cited by

Genes30

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AIFM19,131PubTator's text mininghttps://conductscience.org/library/genes/9131NCBI Gene
BAK1578PubTator's text mininghttps://conductscience.org/library/genes/578NCBI Gene
BAX581PubTator's text mininghttps://conductscience.org/library/genes/581NCBI Gene
BCAP3110,134PubTator's text mininghttps://conductscience.org/library/genes/10134NCBI Gene
BCL2596PubTator's text mininghttps://conductscience.org/library/genes/596NCBI Gene
BCL2L1598PubTator's text mininghttps://conductscience.org/library/genes/598NCBI Gene
CASP3836PubTator's text mininghttps://conductscience.org/library/genes/836NCBI Gene
CASP8841PubTator's text mininghttps://conductscience.org/library/genes/841NCBI Gene
CASP9842PubTator's text mininghttps://conductscience.org/library/genes/842NCBI Gene
CCNA2890PubTator's text mininghttps://conductscience.org/library/genes/890NCBI Gene
CCNE1898PubTator's text mininghttps://conductscience.org/library/genes/898NCBI Gene
CCNL281,669PubTator's text mininghttps://conductscience.org/library/genes/81669NCBI Gene
CDK21,017PubTator's text mininghttps://conductscience.org/library/genes/1017NCBI Gene
CDKN1B1,027PubTator's text mininghttps://conductscience.org/library/genes/1027NCBI Gene
CYBB1,536PubTator's text mininghttps://conductscience.org/library/genes/1536NCBI Gene
CYCS54,205PubTator's text mininghttps://conductscience.org/library/genes/54205NCBI Gene
DAPK223,604PubTator's text mininghttps://conductscience.org/library/genes/23604NCBI Gene
E2F11,869PubTator's text mininghttps://conductscience.org/library/genes/1869NCBI Gene
H3P16644,914PubTator's text mininghttps://conductscience.org/library/genes/644914NCBI Gene
ITGAM3,684PubTator's text mininghttps://conductscience.org/library/genes/3684NCBI Gene

See all 30 genes

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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