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Disease · MONDO_0005108

viral infectious disease

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. viral infectious disease. Diseases, record MONDO_0005108. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0005108

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
viral infectious disease
Open Targets
Open Targets ID
MONDO_0005108
Open Targets
Other names
Viruses caused disease or disorder, Viruses disease or disorder, Viruses infection, Viruses infectious disease, infection, viral, viral disease, viral disorder, viral infection
Open Targets
Disease Ontology
DOID:934
Disease Ontology
MeSH
D014777
MeSH
NCI Thesaurus
C3439
NCI Thesaurus
Highest stage of its drugs
Approval, for 96 of its 134 drugs, from ATC and DailyMed
Open Targets

Drugs134

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
CIDOFOVIRCHEMBL5314375Small moleculeApprovalATC211Drugs and targets
ENISAMIUM IODIDECHEMBL1716983Small moleculeApprovalATC211Drugs and targets
ACYCLOVIRCHEMBL184Small moleculeApprovalATC300Drugs and targets
COBLOPASVIRCHEMBL6068007Small moleculeApprovalATC200Drugs and targets
IDOXURIDINECHEMBL788Small moleculeApprovalATC200Drugs and targets
PENCICLOVIRCHEMBL1540Small moleculeApprovalATC200Drugs and targets
RIBAVIRINCHEMBL1643Small moleculeApprovalATC and DailyMed200Drugs and targets
TROMANTADINECHEMBL3989506Small moleculeApprovalATC200Drugs and targets
ABACAVIRCHEMBL1380Small moleculeApprovalATC100Drugs and targets
ADEFOVIR DIPIVOXILCHEMBL922Small moleculeApprovalATC100Drugs and targets

1 to 10 of 134

See all 134 drugs

Targets10

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
CCR5C-C chemokine receptor type 51C-C chemokine receptor type 5 antagonistApprovalhttps://conductscience.org/library/genes/1234Drugs and targets
CD4T-cell surface glycoprotein CD41T-cell surface antigen CD4 inhibitorApprovalhttps://conductscience.org/library/genes/920Drugs and targets
CYP3A4Cytochrome P450 3A1Cytochrome P450 3A inhibitorApprovalhttps://conductscience.org/library/genes/1576Drugs and targets
CYP3A43Cytochrome P450 3A1Cytochrome P450 3A inhibitorApprovalhttps://conductscience.org/library/genes/64816Drugs and targets
CYP3A5Cytochrome P450 3A1Cytochrome P450 3A inhibitorApprovalhttps://conductscience.org/library/genes/1577Drugs and targets
CYP3A7Cytochrome P450 3A1Cytochrome P450 3A inhibitorApprovalhttps://conductscience.org/library/genes/1551Drugs and targets
DHFRDihydrofolate reductase1Dihydrofolate reductase inhibitorPhase 1/2https://conductscience.org/library/genes/1719Drugs and targets
IMPDH1Inosine-5'-monophosphate dehydrogenase 11Inosine-5'-monophosphate dehydrogenase 1 inhibitorApprovalhttps://conductscience.org/library/genes/3614Drugs and targets
SLC10A1Hepatic sodium/bile acid cotransporter1Bile acid transporter inhibitorApprovalhttps://conductscience.org/library/genes/6554Drugs and targets
TLR7Toll-like receptor 71Toll-like receptor 7 agonistApprovalhttps://conductscience.org/library/genes/51284Drugs and targets

Trials3

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT04682444Efficacy and Safety of Enisamium Iodide for the Treatment of Acute Respiratory Viral Infections, Including Influenza.Phase 2/31002026-01-08Acute Respiratory Viral Infections, Human InfluenzaENISAMIUM IODIDEOpen Targets' reading, confirmed by NLM's indexing of its papersClinicalTrials.gov
NCT01027702Donor Lymphocyte Infusion After Alternative Donor TransplantationPhase 1/2382017-11-08ImmunodeficiencyMETHOTREXATEOpen Targets' reading of its recordClinicalTrials.gov
NCT00956176Cidofovir Instillation in Hematopoietic Stem Cell Transplant (HSCT) Recipients With Hemorrhagic CystitisNot applicable0Cystitis, Bladder DiseasesCIDOFOVIRIts record names the diseaseClinicalTrials.gov

Comparisons in its trials2

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Group 1 - Active Treatment vs Group 2 - Placebo: deaths from any cause0 of 600 of 40100NCT04682444Trial comparisons
Group 1 - Active Treatment vs Group 2 - Placebo: serious adverse events0 of 600 of 40100NCT04682444Trial comparisons

Papers from its trials2

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
33558285DERIVED1PubMed
29047161DERIVED1PubMed

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005108

GET https://conductscience.org/api/diseases/v1/MONDO_0005108/drugs?page=2

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