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Paper30453079

Corneal pain and experimental model development.

McKay TB and 8 others. Prog Retin Eye Res, 2019. Cited by 50 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Corneal pain and experimental model development. Papers, record 30453079. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/30453079

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Corneal pain and experimental model development.
PubMed
Journal
Prog Retin Eye Res
PubMed
Year
2019
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Review
PubMed
Citations, by iCite
50
iCite
Relative citation ratio, by iCite
2.74
iCite
Revised in PubMed
2024-09-22
PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1McKay TBTina B
2Seyed-Razavi YYashar
3Ghezzi CEChiara E
4Dieckmann GGabriela
5Nieland TJFThomas J F
6Cairns DMDana M
7Pollard RERachel E
8Hamrah PPedram
9Kaplan DLDavid L

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CorneaMajor topic
Corneal DiseasesMajor topic
Eye PainMajor topic
NeuralgiaMajor topic
Animals
Humans
Models, Theoretical

Source PubMed

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 EY022695NEI NIH HHSUnited StatesR01EY022695PubMed and NIHNIH RePORTER
R21 EY025393NEI NIH HHSUnited StatesR21EY025393PubMed and NIHNIH RePORTER
R01 EY020856NEI NIH HHSUnited StatesR01EY020856PubMed and NIHNIH RePORTER
R01 EY029602NEI NIH HHSUnited StatesR01EY029602PubMed and NIHNIH RePORTER
R01 AR055993NIAMS NIH HHSUnited StatesR01AR055993PubMed and NIHNIH RePORTER
P41 EB002520NIBIB NIH HHSUnited StatesP41EB002520PubMed and NIHNIH RePORTER

References350

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
122,750,882Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.Nat Biotechnol2012https://conductscience.org/library/papers/22750882PubMed
28,176,415Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves.J Neurocytol1994https://conductscience.org/library/papers/8176415PubMed
37,523,155Basement membrane assembly and differentiation of cultured corneal cells: importance of culture environment and endothelial cell interaction.Exp Cell Res1994https://conductscience.org/library/papers/7523155PubMed
423,340,210P2X7 receptor and cytokines contribute to extra-territorial facial pain.J Dent Res2013https://conductscience.org/library/papers/23340210PubMed
525,416,814TLR9 and TLR7/8 activation induces formation of keratic precipitates and giant macrophages in the mouse cornea.J Leukoc Biol2015https://conductscience.org/library/papers/25416814PubMed
611,113,359Electrophysiological properties of identified trigeminal ganglion neurons innervating the cornea of the mouse.Neuroscience2000https://conductscience.org/library/papers/11113359PubMed
711,425,356The Draize eye test.Surv Ophthalmol2001https://conductscience.org/library/papers/11425356PubMed
819,875,671Human corneal fibrosis: an in vitro model.Invest Ophthalmol Vis Sci2010https://conductscience.org/library/papers/19875671PubMed
915,135,924Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia.Neurosci Lett2004https://conductscience.org/library/papers/15135924PubMed
1020,036,654Anatomy of the human corneal innervation.Exp Eye Res2010https://conductscience.org/library/papers/20036654PubMed
1111,867,578Novel characterization of MHC class II-negative population of resident corneal Langerhans cell-type dendritic cells.Invest Ophthalmol Vis Sci2002https://conductscience.org/library/papers/11867578PubMed
1224,847,207Fractalkine/CX3CR1 signaling during neuropathic pain.Front Cell Neurosci2014https://conductscience.org/library/papers/24847207PubMed
1317,620,569Effect of the ocular microenvironment in regulating corneal dendritic cell maturation.Arch Ophthalmol2007https://conductscience.org/library/papers/17620569PubMed
1424,976,386Network dynamics of 3D engineered neuronal cultures: a new experimental model for in-vitro electrophysiology.Sci Rep2014https://conductscience.org/library/papers/24976386PubMed
1516,962,363Stress-induced corneal epithelial apoptosis mediated by K+ channel activation.Prog Retin Eye Res2006https://conductscience.org/library/papers/16962363PubMed
1615,106,930Neural basis of sensation in intact and injured corneas.Exp Eye Res2004https://conductscience.org/library/papers/15106930PubMed
1716,876,299Report of an ISRTP workshop: progress and barriers to incorporating alternative toxicological methods in the U.S.Regul Toxicol Pharmacol2006https://conductscience.org/library/papers/16876299PubMed
1812,948,308Ex vivo expansion of corneal limbal epithelial/stem cells for corneal surface reconstruction.Eur J Ophthalmol2003https://conductscience.org/library/papers/12948308PubMed
1917,216,083Inflammation in dry eye.Ocul Surf2004https://conductscience.org/library/papers/17216083PubMed
2016,019,187Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals.Toxicol In Vitro2006https://conductscience.org/library/papers/16019187PubMed

See all 350 references

Cited by35

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 50 citations.

PMIDTitleJournalYearIn PapersSource
42,654,754The miR-183/96/182 Cluster Regulates Trigeminal Ganglion Sensory Neurons' Response to Pseudomonas aeruginosa Infection.Pathogens2026https://conductscience.org/library/papers/42654754PubMed
41,959,521The miR-183/96/182 Cluster Regulates Trigeminal Ganglion Sensory Neurons' Response to Pseudomonas aeruginosa Infection.bioRxiv2026https://conductscience.org/library/papers/41959521PubMed
41,899,483Current and Developing Therapeutics for Dry Eye Disease: Targeting Ion Channels.Curr Issues Mol Biol2026https://conductscience.org/library/papers/41899483PubMed
41,692,820Clusterin reverses epitheliopathy, reduces inflammation, and restores goblet cells and corneal nerves in a mouse model of autoimmune dry eye.Sci Rep2026https://conductscience.org/library/papers/41692820PubMed
41,552,884Corneal macrophages and limbal stem cells: emerging roles in ocular surface regeneration.Ann Med2026https://conductscience.org/library/papers/41552884PubMed
41,237,893Current progress in research on ocular injury caused by exposure to vesicants.Prog Retin Eye Res2025https://conductscience.org/library/papers/41237893PubMed
40,919,870P2X4 Receptor Antagonist Ameliorates Ocular Pain in Rats After Lacrimal Gland Removal.Transl Vis Sci Technol2025https://conductscience.org/library/papers/40919870PubMed
40,666,279Tear deficiency transforms spatial distribution of corneal calcitonin gene-related peptide-positive nerves in rats.Front Cell Neurosci2025https://conductscience.org/library/papers/40666279PubMed
40,429,806Corneal Sensory Receptors and Pharmacological Therapies to Modulate Ocular Pain.Int J Mol Sci2025https://conductscience.org/library/papers/40429806PubMed
39,937,496Modeling Neuropathic Corneal Pain: Pulled Nerve Approach With Elevated Krt16 Gene Expression.Invest Ophthalmol Vis Sci2025https://conductscience.org/library/papers/39937496PubMed
39,807,180Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy.Mater Today Bio2025https://conductscience.org/library/papers/39807180PubMed
39,681,161Neuropsin, TRPV4 and intracellular calcium mediate intrinsic photosensitivity in corneal epithelial cells.Ocul Surf2025https://conductscience.org/library/papers/39681161PubMed
39,542,915Morphological aberration of corneal nerves in hyposecretory dry eye guinea pigs.Med Mol Morphol2025https://conductscience.org/library/papers/39542915PubMed
39,495,266Enhancing orofacial pain relief: α-phellandrene complexed with hydroxypropyl-β-cyclodextrin mitigates orofacial nociception in rodents.Naunyn Schmiedebergs Arch Pharmacol2025https://conductscience.org/library/papers/39495266PubMed
39,299,675Corneal epithelial-stromal constructs to study differences associated with diabetes mellitus.Exp Eye Res2024https://conductscience.org/library/papers/39299675PubMed
39,076,769Precise longitudinal monitoring of corneal change through in vivo confocal microscopy in a rat dry eye disease model.Mol Vis2024https://conductscience.org/library/papers/39076769PubMed
38,363,459Corneal Neuropathic Pain: A Patient and Physician Perspective.Ophthalmol Ther2024https://conductscience.org/library/papers/38363459PubMed
37,260,844Collagen mimetic peptide repair of the corneal nerve bed in a mouse model of dry eye disease.Front Neurosci2023https://conductscience.org/library/papers/37260844PubMed
37,111,260Controlled Drug Delivery Device for Cornea Treatment and Novel Method for Its Testing.Pharmaceuticals (Basel)2023https://conductscience.org/library/papers/37111260PubMed
35,566,533Corneal Confocal Microscopy Features and Tear Molecular Profile in Study Participants with Discordance between Ocular Surface Disease Clinical Signs and Discomfort.J Clin Med2022https://conductscience.org/library/papers/35566533PubMed

See all 35 cited by

Genes53

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ACTA158PubTator's text mininghttps://conductscience.org/library/genes/58NCBI Gene
CACNA1B774PubTator's text mininghttps://conductscience.org/library/genes/774NCBI Gene
CACNA1D776PubTator's text mininghttps://conductscience.org/library/genes/776NCBI Gene
CCL36,348PubTator's text mininghttps://conductscience.org/library/genes/6348NCBI Gene
CD4920PubTator's text mininghttps://conductscience.org/library/genes/920NCBI Gene
CNTF1,270PubTator's text mininghttps://conductscience.org/library/genes/1270NCBI Gene
CSF31,440PubTator's text mininghttps://conductscience.org/library/genes/1440NCBI Gene
CX3CL16,376PubTator's text mininghttps://conductscience.org/library/genes/6376NCBI Gene
CX3CR11,524PubTator's text mininghttps://conductscience.org/library/genes/1524NCBI Gene
CXCL83,576PubTator's text mininghttps://conductscience.org/library/genes/3576NCBI Gene
EGF1,950PubTator's text mininghttps://conductscience.org/library/genes/1950NCBI Gene
FASLG356PubTator's text mininghttps://conductscience.org/library/genes/356NCBI Gene
GDNF2,668PubTator's text mininghttps://conductscience.org/library/genes/2668NCBI Gene
GFRA12,674PubTator's text mininghttps://conductscience.org/library/genes/2674NCBI Gene
HLA-C3,107PubTator's text mininghttps://conductscience.org/library/genes/3107NCBI Gene
HMGB13,146PubTator's text mininghttps://conductscience.org/library/genes/3146NCBI Gene
IFNG3,458PubTator's text mininghttps://conductscience.org/library/genes/3458NCBI Gene
IGF13,479PubTator's text mininghttps://conductscience.org/library/genes/3479NCBI Gene
IL103,586PubTator's text mininghttps://conductscience.org/library/genes/3586NCBI Gene
IL17A3,605PubTator's text mininghttps://conductscience.org/library/genes/3605NCBI Gene

See all 53 genes

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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