Disease · EFO_1001898
mucositis
6 sourcesdiseases-2026-09-18-0.1.0
Cite this record
ConductScience Library. mucositis. Diseases, record EFO_1001898. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/EFO_1001898
On this page
Disease
Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.
Drugs21
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Drug | ChEMBL ID | Type | Open Targets' stage | Stage reported by | Reports | Of them trials | Trials shown here | Source |
|---|---|---|---|---|---|---|---|---|
| PALIFERMIN | CHEMBL1201821 | Protein | Approval | DailyMed | 3 | 1 | 0 | Drugs and targets |
| ALANYL GLUTAMINE | CHEMBL3707366 | Small molecule | Approval | TTD | 1 | 0 | 0 | Drugs and targets |
| AMIFOSTINE | CHEMBL1006 | Small molecule | Approval | TTD | 1 | 0 | 0 | Drugs and targets |
| MORPHINE | CHEMBL70 | Small molecule | Phase 3 | ClinicalTrials.gov | 2 | 2 | 2 | Drugs and targets |
| HYDROMORPHONE | CHEMBL398707 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| KETAMINE | CHEMBL742 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| METHADONE | CHEMBL651 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| NALBUPHINE HYDROCHLORIDE | CHEMBL1201132 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| SODIUM FLUORIDE | CHEMBL1528 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| TRICLOSAN | CHEMBL849 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
1 to 10 of 21
See all 21 drugsTargets14
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| OPRM1 | Mu-type opioid receptor | 4 | Mu opioid receptor agonist; Opioid receptors; mu/kappa/delta agonist | Phase 3 | https://conductscience.org/library/genes/4988 | Drugs and targets |
| FGFR2 | Fibroblast growth factor receptor 2 | 1 | Fibroblast growth factor receptor 2 agonist | Approval | https://conductscience.org/library/genes/2263 | Drugs and targets |
| GRIN1 | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/2902 | Drugs and targets |
| GRIN2A | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/2903 | Drugs and targets |
| GRIN2B | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/2904 | Drugs and targets |
| GRIN2C | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/2905 | Drugs and targets |
| GRIN2D | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/2906 | Drugs and targets |
| GRIN3A | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/116443 | Drugs and targets |
| GRIN3B | Glutamate [NMDA] receptor | 1 | Glutamate [NMDA] receptor negative allosteric modulator | Phase 3 | https://conductscience.org/library/genes/116444 | Drugs and targets |
| HMGCR | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1 | HMG-CoA reductase inhibitor | Phase 2 | https://conductscience.org/library/genes/3156 | Drugs and targets |
1 to 10 of 14
See all 14 targetsTrials10
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.
| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01072201 | To Access the Effects of Mucositis in Adults With Dental Implants | Phase 3 | 60 | 2010-02-19 | Mucositis | SODIUM FLUORIDE, TRICLOSAN | Its record names the disease | ClinicalTrials.gov |
| NCT03400475 | Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis | Phase 2 | 46 | 2018-11-29 | Peri-implant Mucositis | SIMVASTATIN | Open Targets' reading of its record | ClinicalTrials.gov |
| NCT04099901 | Anakinra: Efficacy in the Management of Fever During Neutropenia and Mucositis in ASCT - A Randomized Controlled Trial | Phase 2 | 88 | Multiple Myeloma | ANAKINRA | Its record names the disease | ClinicalTrials.gov | |
| NCT03825887 | Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients | Phase 3 | 80 | Acute Myeloid Leukemia, Stem Cell Leukemia | MORPHINE, NALBUPHINE HYDROCHLORIDE | Its record names the disease | ClinicalTrials.gov | |
| NCT01164215 | Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy | Phase 1 | 76 | Colorectal Cancer, Diarrhea, Neutropenia | FLUOROURACIL, LEUCOVORIN CALCIUM, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT06940570 | Methadone as an Alternative Treatment for Children Underdoing HSCT | Phase 3 | 60 | Leukemia, Aplastic Anemia, Bone Marrow Failure Syndromes, SCID | HYDROMORPHONE, METHADONE, MORPHINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00224692 | Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine | Phase 3 | 50 | Cancer, Mucositis | KETAMINE | Its record names the disease | ClinicalTrials.gov | |
| NCT06521112 | The Effect of Oral Care on Mucositis and Oral Mucosa According to Individual Oral Care Frequency Assessment | Not applicable | 41 | Mucositis | CHLORHEXIDINE GLUCONATE | Its record names the disease | ClinicalTrials.gov | |
| NCT00563498 | Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients | Not applicable | 40 | Pulmonary Veno-Occlusive Disease, Hepatic Veno-Occlusive Disease, Mucositis | GLUTAMINE | Its record names the disease | ClinicalTrials.gov | |
| NCT04870060 | Ability of Curcumin to Decrease Cytokines Involved in Mucositis in the Autologous Transplant | Phase 2 | 40 | Oral Mucositis (Ulcerative) | CURCUMIN | Its record names the disease | ClinicalTrials.gov |
Comparisons in its trials2
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Total Toothpaste vs Ultrabrite Toothpaste: serious adverse events | 0 of 30 | 0 of 29 | 59 | NCT01072201 | Trial comparisons |
| Test Group vs Control Group: serious adverse events | 0 of 24 | 0 of 22 | 46 | NCT03400475 | Trial comparisons |
Papers from its trials4
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Data dates
The date of each source this release read.
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this disease from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/diseases/v1/EFO_1001898
GET https://conductscience.org/api/diseases/v1/EFO_1001898/drugs?page=2