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Disease · HP_0030834

Shoulder pain

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. Shoulder pain. Diseases, record HP_0030834. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/HP_0030834

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
Shoulder pain
Open Targets ID
HP_0030834
Highest stage of its drugs
Phase 3, for 2 of its 18 drugs, from ClinicalTrials.gov

Source Open Targets

Drugs18

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
BOTULINUM TOXIN TYPE ACHEMBL4297862ProteinPhase 3ClinicalTrials.gov222Drugs and targets
KETOPROFENCHEMBL571Small moleculePhase 3ClinicalTrials.gov111Drugs and targets
LIDOCAINECHEMBL79Small moleculePhase 2ClinicalTrials.gov555Drugs and targets
HYALURONIDASECHEMBL1201636EnzymePhase 2ClinicalTrials.gov222Drugs and targets
LIDOCAINE HYDROCHLORIDECHEMBL1200409Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
PROPRANOLOLCHEMBL27Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
SODIUM THIOSULFATECHEMBL2096650Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
TRIAMCINOLONECHEMBL1451Small moleculePhase 2ClinicalTrials.gov111Drugs and targets
ZOLPIDEMCHEMBL911Small moleculePhase 1ClinicalTrials.gov111Drugs and targets
BETAMETHASONE DIPROPIONATECHEMBL1200384Small moleculeUnknownClinicalTrials.gov111Drugs and targets

1 to 10 of 18

See all 18 drugs

Targets19

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
NR3C1Glucocorticoid receptor5Glucocorticoid receptor agonistPhase 2https://conductscience.org/library/genes/2908Drugs and targets
SCN4ASodium channel alpha subunit4Sodium channel alpha subunit blocker; Sodium channel protein type IV alpha subunit blockerPhase 2https://conductscience.org/library/genes/6329Drugs and targets
SCN10ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6336Drugs and targets
SCN11ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/11280Drugs and targets
SCN1ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6323Drugs and targets
SCN2ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6326Drugs and targets
SCN3ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6328Drugs and targets
SCN5ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6331Drugs and targets
SCN7ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6332Drugs and targets
SCN8ASodium channel alpha subunit3Sodium channel alpha subunit blockerPhase 2https://conductscience.org/library/genes/6334Drugs and targets

1 to 10 of 19

See all 19 targets

Trials18

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT02620579Biopsychosocial Influence on Shoulder PainPhase 22642023-01-13Shoulder PainPROPRANOLOLIts record names the diseaseClinicalTrials.gov
NCT00597766Subacromial Corticosteroid Injection for Hemiplegic Shoulder PainPhase 2282017-12-13Shoulder PainTRIAMCINOLONEIts record names the diseaseClinicalTrials.gov
NCT00661089Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and SpasticityNot applicable212012-02-06Post-stroke Shoulder Pain and SpasticityBOTULINUM TOXIN TYPE AIts record names the diseaseClinicalTrials.gov
NCT00680472HKT-500 in Adult Patients With Shoulder PainPhase 3368PainKETOPROFENIts record names the diseaseClinicalTrials.gov
NCT04737993Pulsed Radiofrequency of Suprascapular Nerve and Shoulder Joint for Chronic Shoulder PainNot applicable150Chronic Shoulder PainLIDOCAINEIts record names the diseaseClinicalTrials.gov
NCT01393925Effect of Parecoxib on Postoperative Shoulder Pain After Gynecological Laparoscopy.Not applicable126Anti-Inflammatory Agents, Non-Steroidal, Pain, Postoperative, LaparoscopyPARECOXIBIts record names the diseaseClinicalTrials.gov
NCT03269760Multimodal Sleep Pathway for Shoulder ArthroplastyPhase 1122Sleep Disturbance, Shoulder Arthritis, Arthroplasty Complications, Perioperative/Postoperative ComplicationsZOLPIDEMIts record names the diseaseClinicalTrials.gov
NCT04251832Efficacy of Sodium Thiosulfate in Shoulder Pain in Calcific Tendinitis of the Rotator CuffPhase 280Sodium Thiosulfate, Calcific Tendinitis, Shoulder PainSODIUM THIOSULFATEIts record names the diseaseClinicalTrials.gov
NCT06718413Myofascial Dysfunction in Post Stroke Shoulder PainPhase 268StrokeHYALURONIDASEIts record names the diseaseClinicalTrials.gov
NCT05381389Onset and Recovery of Ultrasound Guided Out-of-plane Versus In-plane Interscalene Block in Arthroscopic Shoulder SurgeryNot applicable60AnalgesiaBUPIVACAINE HYDROCHLORIDEIts record names the diseaseClinicalTrials.gov

1 to 10 of 18

See all 18 trials

Comparisons in its trials1

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrial
onabotulinumtoxinA Injection vs Saline Injection: serious adverse events1 of 104 of 1121NCT00661089

Papers from its trials9

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
36686276RESULT1PubMed
33399396RESULT1PubMed
33123644RESULT1PubMed
25523242RESULT1PubMed
23619203RESULT1PubMed
23064478RESULT1PubMed
20961685RESULT1PubMed
35604152DERIVED1PubMed
30327731DERIVED1PubMed

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/HP_0030834

GET https://conductscience.org/api/diseases/v1/HP_0030834/drugs