Disease · MONDO_0006713
Targets15
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
1 to 15 of 15
Download this page as JSON| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| VEGFA | Vascular endothelial growth factor A, long form | 4 | Vascular endothelial growth factor A inhibitor | Phase 3 | https://conductscience.org/library/genes/7422 | Drugs and targets |
| PGF | Placenta growth factor | 2 | Placenta growth factor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/5228 | Drugs and targets |
| CSF1R | Macrophage colony-stimulating factor 1 receptor | 1 | Macrophage colony stimulating factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/1436 | Drugs and targets |
| FGFR1 | Fibroblast growth factor receptor 1 | 1 | Fibroblast growth factor receptor 1 inhibitor | Phase 1/2 | https://conductscience.org/library/genes/2260 | Drugs and targets |
| FGFR3 | Fibroblast growth factor receptor 3 | 1 | Fibroblast growth factor receptor 3 inhibitor | Phase 1/2 | https://conductscience.org/library/genes/2261 | Drugs and targets |
| FLT1 | Vascular endothelial growth factor receptor | 1 | Vascular endothelial growth factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/2321 | Drugs and targets |
| FLT4 | Vascular endothelial growth factor receptor | 1 | Vascular endothelial growth factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/2324 | Drugs and targets |
| ITK | Tyrosine-protein kinase ITK/TSK | 1 | Tyrosine-protein kinase ITK/TSK inhibitor | Phase 1/2 | https://conductscience.org/library/genes/3702 | Drugs and targets |
| KDR | Vascular endothelial growth factor receptor | 1 | Vascular endothelial growth factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/3791 | Drugs and targets |
| KIT | Mast/stem cell growth factor receptor Kit | 1 | Stem cell growth factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/3815 | Drugs and targets |
| LCK | Tyrosine-protein kinase Lck | 1 | Tyrosine-protein kinase LCK inhibitor | Phase 1/2 | https://conductscience.org/library/genes/3932 | Drugs and targets |
| PDGFRA | Platelet-derived growth factor receptor | 1 | Platelet-derived growth factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/5156 | Drugs and targets |
| PDGFRB | Platelet-derived growth factor receptor | 1 | Platelet-derived growth factor receptor inhibitor | Phase 1/2 | https://conductscience.org/library/genes/5159 | Drugs and targets |
| VEGFB | Vascular endothelial growth factor B | 1 | Vascular endothelial growth factor B inhibitor | Phase 1 | https://conductscience.org/library/genes/7423 | Drugs and targets |
| VEGFC | Vascular endothelial growth factor C | 1 | Vascular endothelial growth factor C inhibitor | Phase 1 | https://conductscience.org/library/genes/7424 | Drugs and targets |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0006713/targets