Disease · HP_0001082
Cholecystitis
6 sourcesdiseases-2026-09-18-0.1.0
Cite this record
ConductScience Library. Cholecystitis. Diseases, record HP_0001082. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/HP_0001082
On this page
Disease
Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.
- Name
- Cholecystitis
- Open Targets ID
- HP_0001082
- Other names
- Gallbladder inflammation, Recurrent cholecystitis, Unusual cholecystitis
- Highest stage of its drugs
- Approval, for 6 of its 10 drugs, from PMDA
Source Open Targets
Drugs10
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Drug | ChEMBL ID | Type | Open Targets' stage | Stage reported by | Reports | Of them trials | Trials shown here | Source |
|---|---|---|---|---|---|---|---|---|
| AVIBACTAM SODIUM | CHEMBL2107817 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| CEFTAZIDIME | CHEMBL44354 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| CEFTOLOZANE SULFATE | CHEMBL1213250 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| PIPERACILLIN SODIUM | CHEMBL1200820 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| TAZOBACTAM | CHEMBL404 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| TIGECYCLINE | CHEMBL376140 | Small molecule | Approval | PMDA | 1 | 0 | 0 | Drugs and targets |
| BIPHENYL DIMETHYL DICARBOXYLATE | CHEMBL4297409 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| MOXIFLOXACIN | CHEMBL32 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| CIPROFLOXACIN | CHEMBL8 | Small molecule | Unknown | ClinicalTrials.gov | 2 | 2 | 2 | Drugs and targets |
| ROPIVACAINE | CHEMBL1077896 | Small molecule | Unknown | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
Targets10
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| SCN10A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6336 | Drugs and targets |
| SCN11A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/11280 | Drugs and targets |
| SCN1A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6323 | Drugs and targets |
| SCN2A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6326 | Drugs and targets |
| SCN3A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6328 | Drugs and targets |
| SCN4A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6329 | Drugs and targets |
| SCN5A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6331 | Drugs and targets |
| SCN7A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6332 | Drugs and targets |
| SCN8A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6334 | Drugs and targets |
| SCN9A | Sodium channel alpha subunit | 1 | Sodium channel alpha subunit blocker | Unknown | https://conductscience.org/library/genes/6335 | Drugs and targets |
Trials5
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02494336 | Trans-incisional vs Laparoscopic Guided Rectus Sheath Block for Pediatric Single Incision Laparoscopic Cholecystectomy | Not applicable | 48 | 2020-04-13 | Pain, Postoperative | ROPIVACAINE | Its record names the disease | ClinicalTrials.gov |
| NCT01670435 | Assessment of the Safety and Efficacy of Ciproxan-I.V. in Daily Clinical Practice - Analysis Results From a Post-marketing Surveillance | 3,274 | Infection | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT01690559 | Ciprofloxacin Special Drug Use Investigation - To Investigate the Safety and Efficacy in Patients With Ciprofloxacin iv Administration Without Dilution | 704 | Infection | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT00447304 | Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy | Phase 3 | 644 | Acute Cholecystitis | MOXIFLOXACIN | Its record names the disease | ClinicalTrials.gov | |
| NCT03578055 | BDD With UDCA Therapy After Laparoscopic Cholecystectomy | Phase 3 | 172 | Cholecystitis, Acute, Cholecystitis, Chronic | BIPHENYL DIMETHYL DICARBOXYLATE | Its record names the disease | ClinicalTrials.gov |
Comparisons in its trials4
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Trans-incisional Rectus Sheath Block vs Laparoscopic Guided Rectus Sheath Block: deaths from any cause | 0 of 24 | 0 of 24 | 48 | NCT02494336 | Trial comparisons |
| Trans-incisional Rectus Sheath Block vs Laparoscopic Guided Rectus Sheath Block: Number of Participants With Complications | 0 of 24 | 0 of 24 | 48 | NCT02494336 | Trial comparisons |
| Trans-incisional Rectus Sheath Block vs Laparoscopic Guided Rectus Sheath Block: Number of Participants With Side Effects | 0 of 24 | 0 of 24 | 48 | NCT02494336 | Trial comparisons |
| Trans-incisional Rectus Sheath Block vs Laparoscopic Guided Rectus Sheath Block: serious adverse events | 2 of 24 | 1 of 24 | 48 | NCT02494336 | Trial comparisons |
Papers from its trials2
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Data dates
The date of each source this release read.
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this disease from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/diseases/v1/HP_0001082
GET https://conductscience.org/api/diseases/v1/HP_0001082/drugs