Disease · HP_0030833
Neck pain
6 sourcesdiseases-2026-09-18-0.1.0
Cite this record
ConductScience Library. Neck pain. Diseases, record HP_0030833. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/HP_0030833
On this page
Disease
Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.
- Name
- Neck pain
- Open Targets ID
- HP_0030833
- Highest stage of its drugs
- Phase 3, for 11 of its 20 drugs, from ClinicalTrials.gov
Source Open Targets
Drugs20
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Drug | ChEMBL ID | Type | Open Targets' stage | Stage reported by | Reports | Of them trials | Trials shown here | Source |
|---|---|---|---|---|---|---|---|---|
| LIDOCAINE | CHEMBL79 | Small molecule | Phase 3 | ClinicalTrials.gov | 4 | 4 | 4 | Drugs and targets |
| CAPSAICIN | CHEMBL294199 | Small molecule | Phase 3 | ClinicalTrials.gov | 3 | 3 | 3 | Drugs and targets |
| DEXAMETHASONE | CHEMBL384467 | Small molecule | Phase 3 | ClinicalTrials.gov | 2 | 2 | 2 | Drugs and targets |
| IBUPROFEN | CHEMBL521 | Small molecule | Phase 3 | ClinicalTrials.gov | 2 | 2 | 1 | Drugs and targets |
| OXYGEN | CHEMBL1234886 | Small molecule | Phase 3 | ClinicalTrials.gov | 2 | 2 | 2 | Drugs and targets |
| OZONE | CHEMBL2447938 | Small molecule | Phase 3 | ClinicalTrials.gov | 2 | 2 | 2 | Drugs and targets |
| CAFFEINE | CHEMBL113 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| CANNABIDIOL | CHEMBL190461 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| CANNABINOL | CHEMBL74415 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 0 | Drugs and targets |
| DICLOFENAC | CHEMBL139 | Small molecule | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
1 to 10 of 20
See all 20 drugsTargets30
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| PTGS2 | Cyclooxygenase | 5 | Cyclooxygenase inhibitor; Cyclooxygenase-2 inhibitor | Phase 3 | https://conductscience.org/library/genes/5743 | Drugs and targets |
| PTGS1 | Cyclooxygenase | 4 | Cyclooxygenase inhibitor | Phase 3 | https://conductscience.org/library/genes/5742 | Drugs and targets |
| SCN4A | Sodium channel alpha subunit | 3 | Sodium channel alpha subunit blocker; Sodium channel protein type IV alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6329 | Drugs and targets |
| SCN10A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6336 | Drugs and targets |
| SCN11A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/11280 | Drugs and targets |
| SCN1A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6323 | Drugs and targets |
| SCN2A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6326 | Drugs and targets |
| SCN3A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6328 | Drugs and targets |
| SCN5A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6331 | Drugs and targets |
| SCN7A | Sodium channel alpha subunit | 2 | Sodium channel alpha subunit blocker | Phase 3 | https://conductscience.org/library/genes/6332 | Drugs and targets |
1 to 10 of 30
See all 30 targetsTrials17
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02700815 | Capsaicin + Diclofenac Gel in Acute Back Pain or Neck Pain | Phase 3 | 746 | 2019-05-06 | Acute Pain | CAPSAICIN, DICLOFENAC | Its record names the disease | ClinicalTrials.gov |
| NCT03003000 | Ibuprofen/Caffeine Lower Back or Neck Pain Study | Phase 3 | 635 | 2019-06-07 | Back Pain, Neck Pain | CAFFEINE, IBUPROFEN | Its record names the disease | ClinicalTrials.gov |
| NCT03007420 | A Prospective Controlled Treatment Trial for Post-Traumatic Headaches | Phase 3 | 16 | 2025-10-14 | Post-Traumatic Headaches | DEXAMETHASONE, LIDOCAINE | Its record names the disease | ClinicalTrials.gov |
| NCT00029770 | Chiropractic Care, Medication, and Self-Care for Neck Pain | Phase 2 | 270 | Neck Pain | ACETAMINOPHEN | Its record names the disease | ClinicalTrials.gov | |
| NCT06628466 | Clinical Response of Nuberol Forte in Chronic Neck Pain in Routine Rehabilitation Centers | 150 | Chronic Neck Pain | ACETAMINOPHEN, ORPHENADRINE | Its record names the disease | ClinicalTrials.gov | ||
| NCT00325312 | Subcutaneous Carbon Dioxide Insufflations for Acute Non Specific Neck Pain | Phase 2 | 114 | Neck Pain | CARBON DIOXIDE | Its record names the disease | ClinicalTrials.gov | |
| NCT07462988 | Comparison of Mesotherapy Treatment Doses in Patients With Chronic Non-Specific Neck Pain | Not applicable | 80 | Neck Pain, Mesotherapy | LIDOCAINE, MELOXICAM, SODIUM CHLORIDE | Its record names the disease | ClinicalTrials.gov | |
| NCT04378959 | Lidocaine Patch for Neck Pain | Not applicable | 76 | Neck Pain, Neck Pain, Posterior | LIDOCAINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00429624 | Randomized Controlled Trial of Chiropractic Manipulation Versus Medical Therapy for Chronic Neck Pain | Not applicable | 70 | Neck Pain | ACETAMINOPHEN | Its record names the disease | ClinicalTrials.gov | |
| NCT07275320 | Cervical Retrolaminar Block Versus Cervical Epidural Injection for Cervical Radiculopathy | Not applicable | 70 | Cervical Radiculopathy | BUPIVACAINE, DEXAMETHASONE | Its record names the disease | ClinicalTrials.gov |
1 to 10 of 17
See all 17 trialsComparisons in its trials0
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
None in this release.
Papers from its trials11
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Data dates
The date of each source this release read.
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this disease from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/diseases/v1/HP_0030833
GET https://conductscience.org/api/diseases/v1/HP_0030833/targets?page=2