Disease · MONDO_0010602
Targets93
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
1 to 20 of 93
Download this page as JSON| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| F8 | Coagulation factor VIII | 14 | Coagulation factor VIII exogenous gene; Coagulation factor VIII exogenous protein | Approval | https://conductscience.org/library/genes/2157 | Drugs and targets |
| F9 | Coagulation factor IX | 4 | Coagulation factor IX and X other; Coagulation factor IX exogenous protein | Approval | https://conductscience.org/library/genes/2158 | Drugs and targets |
| IFNAR1 | Interferon alpha/beta receptor | 3 | Interferon alpha/beta receptor agonist | Phase 2 | https://conductscience.org/library/genes/3454 | Drugs and targets |
| IFNAR2 | Interferon alpha/beta receptor | 3 | Interferon alpha/beta receptor agonist | Phase 2 | https://conductscience.org/library/genes/3455 | Drugs and targets |
| TFPI | Tissue factor pathway inhibitor | 3 | Tissue factor pathway inhibitor inhibitor | Approval | https://conductscience.org/library/genes/7035 | Drugs and targets |
| F7 | Coagulation factor VII | 2 | Coagulation factor VII exogenous protein | Approval | https://conductscience.org/library/genes/2155 | Drugs and targets |
| AVPR1A | Vasopressin receptor | 1 | Vasopressin receptor agonist | Unknown | https://conductscience.org/library/genes/552 | Drugs and targets |
| AVPR1B | Vasopressin receptor | 1 | Vasopressin receptor agonist | Unknown | https://conductscience.org/library/genes/553 | Drugs and targets |
| AVPR2 | Vasopressin receptor | 1 | Vasopressin receptor agonist | Unknown | https://conductscience.org/library/genes/554 | Drugs and targets |
| F10 | Coagulation factor IX and X | 1 | Coagulation factor IX and X other | Approval | https://conductscience.org/library/genes/2159 | Drugs and targets |
| FAU | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/2197 | Drugs and targets |
| IL11RA | Interleukin-11 receptor subunit alpha | 1 | Interleukin 11 receptor alpha agonist | Phase 2 | https://conductscience.org/library/genes/3590 | Drugs and targets |
| MS4A1 | B-lymphocyte antigen CD20 | 1 | B-lymphocyte antigen CD20 binding agent | Phase 2 | https://conductscience.org/library/genes/931 | Drugs and targets |
| PLG | Plasminogen | 1 | Plasminogen inhibitor | Approval | https://conductscience.org/library/genes/5340 | Drugs and targets |
| RPL10 | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/6134 | Drugs and targets |
| RPL10A | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/4736 | Drugs and targets |
| RPL11 | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/6135 | Drugs and targets |
| RPL12 | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/6136 | Drugs and targets |
| RPL13 | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/6137 | Drugs and targets |
| RPL13A | 80S Ribosome | 1 | 80S Ribosome modulator | Phase 2 | https://conductscience.org/library/genes/23521 | Drugs and targets |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0010602/targets