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hemophilia B
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Disease · MONDO_0010604

Targets83

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

1 to 20 of 83

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TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
F9Coagulation factor IX7Coagulation factor IX exogenous gene; Coagulation factor IX exogenous proteinApprovalhttps://conductscience.org/library/genes/2158Drugs and targets
F8Coagulation factor VIII5Coagulation factor VIII exogenous proteinPhase 3https://conductscience.org/library/genes/2157Drugs and targets
TFPITissue factor pathway inhibitor3Tissue factor pathway inhibitor inhibitorApprovalhttps://conductscience.org/library/genes/7035Drugs and targets
F7Coagulation factor VII2Coagulation factor VII exogenous proteinApprovalhttps://conductscience.org/library/genes/2155Drugs and targets
FAU80S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/2197Drugs and targets
RPL1080S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6134Drugs and targets
RPL10A80S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/4736Drugs and targets
RPL1180S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6135Drugs and targets
RPL1280S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6136Drugs and targets
RPL1380S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6137Drugs and targets
RPL13A80S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/23521Drugs and targets
RPL1480S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/9045Drugs and targets
RPL1580S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6138Drugs and targets
RPL1780S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6139Drugs and targets
RPL1880S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6141Drugs and targets
RPL18A80S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6142Drugs and targets
RPL1980S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6143Drugs and targets
RPL2180S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6144Drugs and targets
RPL2280S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/6146Drugs and targets
RPL2380S Ribosome180S Ribosome modulatorPhase 2https://conductscience.org/library/genes/9349Drugs and targets

diseases-2026-09-18-0.1.0

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Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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