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Arthralgia
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Disease · HP_0002829

Targets57

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

1 to 20 of 57

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TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in GenesSource
PTGS2Cyclooxygenase16Cyclooxygenase inhibitor; Cyclooxygenase-2 inhibitorApprovalhttps://conductscience.org/library/genes/5743Drugs and targets
PTGS1Cyclooxygenase15Cyclooxygenase inhibitorApprovalhttps://conductscience.org/library/genes/5742Drugs and targets
PGRProgesterone receptor2Progesterone receptor agonistUnknownhttps://conductscience.org/library/genes/5241Drugs and targets
TRPV1Transient receptor potential cation channel subfamily V member 12Vanilloid receptor agonist; Vanilloid receptor openerApprovalhttps://conductscience.org/library/genes/7442Drugs and targets
ADRA1AAdrenergic receptor alpha1Adrenergic receptor alpha antagonistApprovalhttps://conductscience.org/library/genes/148Drugs and targets
ADRA1BAdrenergic receptor alpha1Adrenergic receptor alpha antagonistApprovalhttps://conductscience.org/library/genes/147Drugs and targets
ADRA1DAdrenergic receptor alpha1Adrenergic receptor alpha antagonistApprovalhttps://conductscience.org/library/genes/146Drugs and targets
ADRA2AAdrenergic receptor alpha1Adrenergic receptor alpha antagonistApprovalhttps://conductscience.org/library/genes/150Drugs and targets
ADRA2BAdrenergic receptor alpha1Adrenergic receptor alpha antagonistApprovalhttps://conductscience.org/library/genes/151Drugs and targets
ADRA2CAdrenergic receptor alpha1Adrenergic receptor alpha antagonistApprovalhttps://conductscience.org/library/genes/152Drugs and targets
ALOX5Polyunsaturated fatty acid 5-lipoxygenase1Arachidonate 5-lipoxygenase inhibitorApprovalhttps://conductscience.org/library/genes/240Drugs and targets
CACNA1AVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/773Drugs and targets
CACNA1BVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/774Drugs and targets
CACNA1CVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/775Drugs and targets
CACNA1DVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/776Drugs and targets
CACNA1EVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/777Drugs and targets
CACNA1FVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/778Drugs and targets
CACNA1GVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/8913Drugs and targets
CACNA1HVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/8912Drugs and targets
CACNA1IVoltage-gated calcium channel1Voltage-gated calcium channel modulatorPhase 2https://conductscience.org/library/genes/8911Drugs and targets

diseases-2026-09-18-0.1.0

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Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/diseases/v1/HP_0002829/targets

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